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Nonsexual Transmission Of Anogenital Warts In Children: A Retrospective Analysis, Valerie Jones, Shawn J. Smith, Hatim A. Omar

Pediatrics Faculty Publications

The purpose was to evaluate the prevalence of sexual abuse in patients who were referred to a pediatric gynecologist for evaluation based on the clinical findings of anogenital warts. A retrospective analysis was performed on 131 patients between the ages 6 month and 9 years referred to a pediatric gynecologist after the finding of anogenital warts by a clinical provider, parent or caregiver. A complete physical examination under colposcopy by a the same, trained pediatric gynecologist was completed, and a complete medical and family history including maternal and sibling history for evidence of Human Papillomavirus (HPV) and anogenital warts. The …

Methicillin-Susceptible Staphylococcus Aureus Colonization In The Neonatal Intensive Care Unit, Shoaib Syed Ahmed

Yale Medicine Thesis Digital Library

Introduction: Nasal carriage of Staphylococcus aureus is a sensitive indicator of staphylococcal colonization and is considered a source of subsequent infection. When the incidence of Staphylococcus aureus colonization increased in our neonatal intensive care unit (NICU), resulting in 3 methicillin-resistant Staphylococcus aureus (MRSA) infections over a 3 month period, we sought to further our understanding of S. aureus epidemiology and response to infection control practice. The purpose of this investigation was to study the methicillin-susceptible Staphylococcus aureus (MSSA), and further determine the clonal spread of MSSA strain types. Since few studies have analyzed the clinical profile of MSSA in neonates, …

Azithromycin In The Extremely Low Birth Weight Infant For The Prevention Of Bronchopulmonary Dysplasia: A Pilot Study, Hubert O. Ballard, Michael I. Anstead, Lori A. Shook

Pediatrics Faculty Publications

BACKGROUND: Azithromycin reduces the severity of illness in patients with inflammatory lung disease such as cystic fibrosis and diffuse panbronchiolitis. Bronchopulmonary dysplasia (BPD) is a pulmonary disorder which causes significant morbidity and mortality in premature infants. BPD is pathologically characterized by inflammation, fibrosis and impaired alveolar development. The purpose of this study was to obtain pilot data on the effectiveness and safety of prophylactic azithromycin in reducing the incidence and severity of BPD in an extremely low birth weight (< or = 1000 grams) population.

METHODS: Infants < or = 1000 g birth weight admitted to the University of Kentucky Neonatal Intensive Care Unit (level III, regional referral center) from 9/1/02-6/30/03 were eligible for this pilot study. The pilot study was double-blinded, randomized, and placebo-controlled. Infants were randomized to treatment or placebo within 12 hours of beginning mechanical ventilation (IMV) and within 72 hours of birth. The treatment group received azithromycin 10 mg/kg/day for 7 days followed by 5 mg/kg/day for the duration of the study. Azithromycin or placebo was continued until the infant no longer required IMV or supplemental oxygen, to a maximum of 6 weeks. Primary endpoints were incidence of BPD as defined by oxygen requirement at 36 weeks gestation, post-natal steroid use, days of IMV, and mortality. Data was analyzed by intention to treat using Chi-square and ANOVA.

RESULTS: A total of 43 extremely premature infants were enrolled in this pilot study. Mean gestational age and …

Barriers To Influenza Immunization: The Role Of Physician Training On Influenza Vaccine Utilization In Six To Twenty-Three Month Old Infants, John D. Shanley

UCHC Graduate School Masters Theses 2003 - 2010

Digital Preservation

Playing With Daddy: Social Toy Play, Early Head Start, And Developmental Outcomes, Lori A. Roggman, Lisa Bouye, G. A. Cook, K. Christiansen, D. Jones

Human Development and Family Studies Faculty Publications

Research on fathers in Early Head Start (EHS) has provided an opportunity to study fathers from low-income families. We examined father-toddler social toy play in relation to EHS enrollment, fathers' psychosocial well-being, and children's developmental outcomes in a sample of 74 father-toddler dyads. Overall, our results show that father-toddler social toy play was more complex among fathers in an EHS program than among those in a comparison group. Greater complexity in father-toddler social toy play predicted better cognitive and social developmental outcomes for young children, especially in the program group, but it was limited by fathers' psychosocial well-being in the …

Birth To Three Early Intervention Parent Handbook, Sarah C. Nicholas

Occupational Therapy Capstones

The purpose of this study was to investigate family-centered advocacy in early intervention, specifically the development of a parent handbook for families of young children who are eligible to receive early intervention services in Wyoming. Early intervention programs provide services for children with disabilities ages birth to three and their families under the Individuals with Disabilities Education Improvement Act (2004), Part C. The resource handbook was designed for parents and community partners so that they may better understand and utilize early intervention in the community where they reside. The parent handbook was designed to be as a written reference of …

Resilient Parenting: Overcoming Poor Parental Bonding, W. Travis, Terri Combs-Orme

Terri Combs-Orme

This study identified groups of mothers with varying patterns of adaptive functioning and bonds with their own parents. These patterns were related to mothers' parenting of their own children to understand how some mothers avoid repeating the cycle of poor parenting. Data from 210 new mothers were analyzed before hospital discharge about bonding with their caregivers during childhood and six to 12 months later about adaptive functioning, life circumstances, and parenting. Latent cluster analysis identified four distinct groups of mothers with regard to parental bonds and adaptive functioning: positive-adaptive mothers (good bonding and good adaptive functioning), positive-maladaptive mothers (good bonding …

Homocysteine Levels In Preterm Infants: Is There An Association With Intraventricular Hemorrhage? A Prospective Cohort Study., Wendy J Sturtz, Kathleen H Leef, Amy B Mackley, Shailja Sharma, Teodoro Bottiglieri, David A Paul

Department of Pediatrics Faculty Papers

BACKGROUND: The purpose of this study was to characterize total homocysteine (tHcy) levels at birth in preterm and term infants and identify associations with intraventricular hemorrhage (IVH) and other neonatal outcomes such as mortality, sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, and thrombocytopenia. METHODS: 123 infants < 32 weeks gestation admitted to our Level III nursery were enrolled. A group of 25 term infants were enrolled for comparison. Two blood spots collected on filter paper with admission blood drawing were analyzed by a high performance liquid chromatography (HPLC) method. Statistical analysis included ANOVA, Spearman's Rank Order Correlation and Mann-Whitney U test. RESULTS: The median tHcy was 2.75 micromol/L with an interquartile range of 1.34 - 4.96 micromol/L. There was no difference between preterm and term tHcy (median 2.76, IQR 1.25 - 4.8 micromol/L vs median 2.54, IQR 1.55 - 7.85 micromol/L, p = 0.07). There was no statistically significant difference in tHcy in 31 preterm infants with IVH compared to infants without IVH (median 1.96, IQR 1.09 - 4.35 micromol/L vs median 2.96, IQR 1.51 - 4.84 micromol/L, p = 0.43). There was also no statistically significant difference in tHcy in 7 infants with periventricular leukomalacia (PVL) compared to infants without PVL (median 1.55, IQR 0.25 - 3.45 micromol/L vs median 2.85, IQR 1.34 - 4.82 micromol/L, p = 0.07). Male infants had lower tHcy compared to female; prenatal steroids were associated with a higher tHcy. CONCLUSION: In our population of preterm infants, there is no association between IVH and tHcy. Male gender, prenatal steroids and preeclampsia were associated with differences in tHcy levels.

Resilient Parenting: Overcoming Poor Parental Bonding, W. Travis, Terri Combs-Orme

Social Work Publications and Other Works

This study identified groups of mothers with varying patterns of adaptive functioning and bonds with their own parents. These patterns were related to mothers' parenting of their own children to understand how some mothers avoid repeating the cycle of poor parenting. Data from 210 new mothers were analyzed before hospital discharge about bonding with their caregivers during childhood and six to 12 months later about adaptive functioning, life circumstances, and parenting. Latent cluster analysis identified four distinct groups of mothers with regard to parental bonds and adaptive functioning: positive-adaptive mothers (good bonding and good adaptive functioning), positive-maladaptive mothers (good bonding …

Chart Review: Identification Of Torticollis And Plagiocephaly In An Infant Toddler Screening Program, Kari Ell, Cara Mobley

Physical Therapy Scholarly Projects

As the incidence of torticollis and plagiocephaly have increased since the initiation of the Back to Sleep campaign in 1992, greater awareness of diagnosis and prevention for these conditions is imperative. The purpose of this study was to complete a chart review which identified the bIrth history risk factors and diagnostic indicators for torticollis and plagiocephaly that were documented, the variations in identification and referrals by discipline of screener, and the incidence of torticollis and plagiocephaly in infants and toddlers receiving services through a rural screening program of a midwestern state. A retrospective chart review of 125 children (birth to …

Informed Consent For Routine Infant Circumcision: A Proposal, David Solomon

NYLS Law Review

No abstract provided.