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Effects Of Vasoactive Agents On The Mechanical Properties Of Aortic Heart Valve Leaflets, Rebecca Lynn Pounders Mathis
Effects Of Vasoactive Agents On The Mechanical Properties Of Aortic Heart Valve Leaflets, Rebecca Lynn Pounders Mathis
Theses and Dissertations
Heart valve disease is currently one of the leading forms of heart disease. Current literature has shown that endothelin I, angiotension II and 5-HT are vasoactive agents which cause concentration dependent contractions in aortic valve leaflet tissue. This study tested the mechanical properties of leaflets cut in the radial direction after they were exposed to the agents at varied concentrations or for 0.5, 6 or 24 hours. The elastic modulus, ultimate tensile strength and the yield strength were calculated. In the time trials the elastic modulus and the ultimate tensile strength both showed a significant increase at 24-hours. However, there …
Angiotensin Ii Mediated Regulation Of Signal Transduction In Metabolic Syndrome And Cancer, Ravindra Bharatrao Kolhe
Angiotensin Ii Mediated Regulation Of Signal Transduction In Metabolic Syndrome And Cancer, Ravindra Bharatrao Kolhe
Theses and Dissertations
Patients suffering from hypertension often develop non-Insulin dependent diabetes mellitus (NIDDM), a condition caused by Insulin resistance. Though these patients have normal Insulin receptor (IR) and high levels of Insulin in blood, they fail to have IR-mediated signaling essential for glucose uptake and availability. NIDDM usually begins as insulin resistance, a condition in which Insulin Receptor (IR)-mediated signaling that leads to glucose uptake and glucose availability to cells is inhibited even in the presence of high levels of Insulin in blood. Mechanisms for the development of this Insulin resistance in patients suffering from hypertension are unclear. Angiotensin II (Ang II) …
The Association Of Hypertension Diagnosis With Smoking Cessation: Application Of Multiple Logistic Regression Using Biostatistical And Epidemiological Methods, Latonia Clay
Mathematics Theses
The Association of Hypertension Diagnosis with Smoking Cessation: Application of Multiple Logistic Regression Using Biostatistical and Epidemiological Methods by LaTonia A. Clay Under the Direction of Yu-Sheng Hsu, PhD. ABSTRACT Hypertension and smoking are two major issues threatening the nation’s health. Previous studies examining their relationship have resulted in conflicting reports. The aim of this study is to determine if a relationship exists between smoking cessation and hypertension diagnosis. Data from the Third National Health and Nutrition Examination Survey (NHANES III) were used in this investigation. Physical examination measurements of blood pressure and self-reported diagnosis and smoking behavior were used …
The Prevalence Of Undiagnosed Hypertension In Ambulatory Emergency Department Patients And Lack Of Adequate Referral, Andrew Nerlinger
The Prevalence Of Undiagnosed Hypertension In Ambulatory Emergency Department Patients And Lack Of Adequate Referral, Andrew Nerlinger
Yale Medicine Thesis Digital Library
OBJECTIVES: According to a WHO estimate, 1 in every 8 deaths worldwide is due to high blood pressure (BP). The Emergency Department (ED) provides an opportunity to identify individuals with undiagnosed hypertension (HTN) and refer them for BP recheck. The study objectives were to quantify the population in need referral for BP recheck and to determine the frequency of referral from the ED. METHODS: A retrospective, structured chart review of all patients > 18 years old seen in an urban adult ED over 5 days, excluding major trauma and pregnant pts. Patients with any systolic BP (SBP) > 140 or diastolic BP …
Prevalensi Dan Determinan Hipertensi Di Pulau Jawa, Tahun 2004, Zamhir Setiawan
Prevalensi Dan Determinan Hipertensi Di Pulau Jawa, Tahun 2004, Zamhir Setiawan
Kesmas
Hipertensi merupakan faktor risiko utama kardiovaskuler yang merupakan penyebab utama kematian di seluruh dunia. Peningkatan umur harapan hidup dan perubahan gaya hidup meningkatkan faktor risiko hipertensi di berbagai negara. Tujuan penelitian ini (1) Mengetahui prevalensi hipertensi dan penyebarannya di Pulau Jawa tahun 2004. (2) Mengetahui faktor-faktor sosiodemografi yang berhubungan dengan kejadian hipertensi. (3) Mengetahui kontribusi dan dampak potensial masing masing faktor tersebut. Penelitian dengan rancangan studi Ekologi Multilevel ini menggabungkan variabel tingkat pengukuran individu dengan tingkat pengukuran ekologi dalam analisis bersama, dengan unit analisis individu. Analisis kontekstual dilakukan melalui kerangka konsep hipertensi, menggunakan metode analisis regresi logistik ganda, dengan status …
A Needs Assessment Of Hypertension In Georgia, Faye Lopez, Marylen Rimando, Harshali Khapekar
A Needs Assessment Of Hypertension In Georgia, Faye Lopez, Marylen Rimando, Harshali Khapekar
Journal of the Georgia Public Health Association
Hypertension is a leading cause of stroke, coronary artery disease, heart attack, and heart and kidney failure in the United States. In Georgia, the percentage of those with hypertension and related diseases remain above the national average. The aim of this paper is to offer a basic review of hypertension including physical complications of the disease and to provide statistics regarding the scope of hypertension in the state of Georgia. Additionally, the paper provides insights on current hypertension programs such as the National High Blood Pressure Education Program (NHBPEP) and Dietary Approaches to Stop Hypertension (DASH). In conclusion, a statewide …
Characterization Of Hypertension Through Multivariate Analysis Utilizing Linear And Nonlinear Methods, Diane L. Donnelly
Characterization Of Hypertension Through Multivariate Analysis Utilizing Linear And Nonlinear Methods, Diane L. Donnelly
Dissertations
Analysis of blood pressure by nonlinear methods is vastly underutilized in current research. As such, 24-hour ambulatory blood pressure data from a small cohort of borderline hypertensive and normotensive subjects were analyzed using linear and nonlinear methods. Data were collected and provided by researchers from Columbia University. The cohort size was twelve subjects, consisting of two groups of six each. Although disease state was known, group membership for individual subjects was not. Therefore, one aspect of this research was to separate the cohort, a-priori, into two distinct, evenly sized groups, based solely on analysis results. Separation was accomplished by the …
A Comparison Of Systolic Blood Pressure In Women With And Without Lymphedema Following Surgery For Breast Cancer, Deborah M. Arvidson-Hawkins
A Comparison Of Systolic Blood Pressure In Women With And Without Lymphedema Following Surgery For Breast Cancer, Deborah M. Arvidson-Hawkins
USF Tampa Graduate Theses and Dissertations
There is no evidenced-based research on prevention of upper extremity lymphedema following breast cancer treatment. General guidelines have been identified from a basic understanding of the lymphatic system and are considered to be prudent advice for prevention. Cause of lymphedema is hypothesized to be multifactorial and time of onset is widely varied. Exogenous risk factors leading to lymphedema are the removal and destruction of lymph nodes; however, not all women develop lymphedema following axillary lymph node dissection. Co-morbid conditions such as obesity, diabetes, and hypertension are cited as possible endogenous risk factors. Several studies identify hypertension as a significance endogenous …
Hypertension And Kidney Disease In Asia, Tazeen H. Jafar
Hypertension And Kidney Disease In Asia, Tazeen H. Jafar
Section of Nephrology
PURPOSE OF REVIEW: Communicable diseases were traditionally the major cause of public health concern in Asian countries, most of which were less developed. With industrialization and associated lifestyle changes during the past few decades, however, noncommunicable diseases similar to those that affect Western societies have emerged in Asian countries. The purpose of the review was to examine recent evidence about the burden and factors associated with hypertension and chronic kidney disease (CKD) in Asian countries.RECENT FINDINGS: Hypertension has become one of the leading causes of mortality in Asia. Although its prevalence continues to rise, it remains under-diagnosed and under-treated. CKD …
The Relationship Between Health Beliefs And Adherence To Treatment Of Russian Immigrants With Hypertension, Michael R. Kolesnikov
The Relationship Between Health Beliefs And Adherence To Treatment Of Russian Immigrants With Hypertension, Michael R. Kolesnikov
Master's Projects
Introduction: Hypertension (HTN) has been identified as a common health problem in every ethnic group in the USA. Due to the silent nature of the HTN, some cultures may not perceive this condition as being serious or potentially fatal. Objective: The purpose of this study was to investigate the health beliefs of Russian-speaking immigrants with hypertension and their adherence to the prescribed treatment. Design: The study was a non-experimental exploratory survey and interview. Convenience sampling was used. The Health Belief Model (HBM) provided the theoretical framework. Sample: A total of 62 subjects (27% male and 73% female, ages from 51 …
Lung Circulation Modeling: Status And Prospect, Anne V. Clough, Said H. Audi, Robert C. Molthen, Gary S. Krenz
Lung Circulation Modeling: Status And Prospect, Anne V. Clough, Said H. Audi, Robert C. Molthen, Gary S. Krenz
Biomedical Engineering Faculty Research and Publications
Mathematical modeling has been used to interpret anatomical and physiological data obtained from metabolic and hemodynamic studies aimed at investigating structure-function relationships in the vasculature of the lung, and how these relationships are affected by lung injury and disease. The indicator dilution method was used to study the activity of redox processes within the lung. A steady-state model of the data was constructed and used to show that pulmonary endothelial cells may play an important role in reducing redox active compounds and that those reduction rates can be altered with oxidative stress induced by exposure to high oxygen environments. In …
Cognitive, Emotional, And Quality Of Life Outcomes In Patients With Pulmonary Arterial Hypertension, Ramona O. Hopkins, Joanne White, Eric W. Glissmehyer, Natalie Kitterman, C. Gregory Elliott
Cognitive, Emotional, And Quality Of Life Outcomes In Patients With Pulmonary Arterial Hypertension, Ramona O. Hopkins, Joanne White, Eric W. Glissmehyer, Natalie Kitterman, C. Gregory Elliott
Faculty Publications
Background- The effects of pulmonary arterial hypertension on cardiovascular and physical function are well documented. Limited information exists regarding the effects of pulmonary arterial hypertension on cognitive function despite patient reports of problems with memory and attention. Our primary purpose was to determine if a prospectively identified cohort of pulmonary arterial hypertension patients had cognitive sequelae. Our secondary purpose was to determine the relationships between cognitive sequelae and neuropsychological test scores with depression, anxiety, and quality of life. Methods- Forty-six adults with pulmonary arterial hypertension underwent assessment of cognitive function, depression, anxiety, and quality of life using standardized neuropsychological tests …
Renal Dysfunction, Cardiovascular Risk, And The Response To Ace Inhibition In Patients After Myocardial Infarction, Powell Oliapuram Jose
Renal Dysfunction, Cardiovascular Risk, And The Response To Ace Inhibition In Patients After Myocardial Infarction, Powell Oliapuram Jose
Yale Medicine Thesis Digital Library
Background: Proteinuria is a known cardiovascular risk factor in hypertensive or diabetic patients as well as the general population. Worsening renal function (WRF) has been shown to influence outcomes in the heart failure population. The prognostic value of these markers for renal dysfunction in patients after myocardial infarction is unclear. Methods: The Survival and Ventricular Enlargement trial (SAVE) randomized 2231 patients with left ventricular dysfunction between 3-16 days (average 11 days) post-MI to receive captopril or placebo; those with a serum creatinine above 2.5mg/dl were excluded from SAVE. WRF was defined as an increase in creatinine greater-than 0.3mg/dl measured from …
Richard Lifton, 2005, The Rockefeller University
Richard Lifton, 2005, The Rockefeller University
Harvey Society Lectures
Richard P. Lifton. Genetic dissection of human blood pressure variation: common pathways for rare phenotypes