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Limited Functional Redundancy And Oscillation Of Cyclins In Multinucleated Ashbya Gossypii Fungal Cells, A. Katrin Hungerbuehler, Peter Philippsen, Amy S. Gladfelter

Dartmouth Scholarship

Cyclin protein behavior has not been systematically investigated in multinucleated cells with asynchronous mitoses. Cyclins are canonical oscillating cell cycle proteins, but it is unclear how fluctuating protein gradients can be established in multinucleated cells where nuclei in different stages of the division cycle share the cytoplasm. Previous work in A. gossypii, a filamentous fungus in which nuclei divide asynchronously in a common cytoplasm, demonstrated that one G1 and one B-type cyclin do not fluctuate in abundance across the division cycle. We have undertaken a comprehensive analysis of all G1 and B-type cyclins in A. gossypii to determine whether …

Chemistry Multiple Course Revisions Form 11/14/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Chemistry Multiple Course Revisions Form 2 11/14/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Tetrakis(N-Ethyl-9-Oxo-4-Azonia-5-Aza-9h-Fluorene) Tetra-Μ3-Iodo-Hexa-Μ2-Iodo-Dodecaiodohexabismuthate, Meredith A. Tershany, Andrea M. Goforth, Mark D. Smith, Leroy Peterson Jr., Hans-Conrad Zur Loye

Faculty Publications

The new iodobismuthate compound (C₁₃H₁₁N₂O)₄[Bi₆I₂₂] has been synthesized solvothermally by reacting BiI₃, Zn(NO₃)₂·6H₂O and 4,5-diazafluoren-9-one in a water/ethanol solvent mixture. The asymmetric unit of the compound contains two independent [N-ethyl-4,5-dafo]⁺ cations and one-half of a centrosymmetric [Bi₆I₂₂]^4- anion. The average terminal Bi-I, Bi-₂-I and Bi-₃-I bond lengths in the anion are 2.8923 (2), 3.1403 (2) and 3.3022 (2) Å, respectively.

Richard J. Garascia (Audio, Transcript), Richard J. Garascia, Thomas Kennealy, Tim Mccabe

Oral Histories

Dr. Richard J. Garascia’s remarkable Xavier University career spanned the years 1942 to 1985. In this conversation he talks about his family, his long career as a chemistry professor, and various persons on the Xavier faculty and in administration.

Chemistry Discipline Assessment Report Fall 2006, Chemistry Discipline

Assessment of Student Learning Reports

No abstract provided.

Computer Science B.A. Program And Curriculum Approval 09/28/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Csci 1021 Course Proposal 09/27/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Csci 2601 Course Proposal 09/27/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Computer Science Minor Program And Curriculum Approval 09/26/2007, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Computer Science Multiple Course Revisions Form 09/26/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Chemistry Minor Program And Curriculum Approval 09/26/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Chemistry B.A. Program And Curriculum Approval 09/26/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Computer Science Form A: Discipline Summary 09/18/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Chemistry Form A: Discipline Summary 09/14/2006, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Erv26p Directs Pro-Alkaline Phosphatase Into Endoplasmic Reticulum–Derived Coat Protein Complex Ii Transport Vesicles, Catherine A. Bue, Christine M. Bentivoglio, Charles Barlowe

Dartmouth Scholarship

Secretory proteins are exported from the endoplasmic reticulum (ER) in transport vesicles formed by the coat protein complex II (COPII). We detected Erv26p as an integral membrane protein that was efficiently packaged into COPII vesicles and cycled between the ER and Golgi compartments. The erv26Δ mutant displayed a selective secretory defect in which the pro-form of vacuolar alkaline phosphatase (pro-ALP) accumulated in the ER, whereas other secretory proteins were transported at wild-type rates. In vitro budding experiments demonstrated that Erv26p was directly required for packaging of pro-ALP into COPII vesicles. Moreover, Erv26p was detected in a specific complex with pro-ALP …

Tetrakis[2-(2-Pyridyl)Pyridinium] Tetra-Μ3-Iodo-Hexa-Μ2-Iodo-Dodecaiodohexabismuthate And Bis[Tris(2,2'-Bipyridine)Ruthenium(Ii)] Di-Μ4-Iodo-Octa-Μ2-Iodo-Dodecaiodohexabismuthate, Andrea M. Goforth, Meredith A. Tershansy, Mark D. Smith, Leroy Peterson Jr., Hans-Conrad Zur Loye

Faculty Publications

Crystals of the title compounds were grown solvothermally in an ethanol-water solvent mixture using ruthenium triiodide, 2,2'-bipyridine and bismuth triiodide as starting materials. Tetrakis[2-(2-pyridyl)pyridinium] tetra-₃-iodo-hexa-₂-iodo-dodecaiodohexabismuthate, (C₁₀H₉N₂)₄[Bi₆I₂₂], crystallizes in the triclinic space group P and is the major reaction product. The asymmetric unit of this compound consists of half a centrosymmetric [Bi₆I₂₂]^4- anion and two independent 2,2'-bipyridinium cations. The minor product of the reaction is bis[tris(2,2'-bipyridine)ruthenium(II)] di-₄-iodo-octa-₂-iodo-dodecaiodohexabismuthate, [Ru(C₁₀H₈N₂)₃] …

Water Solubility Characteristics Of Hydrophobically Modified Polyethyleneimines, Jennifer N. Williams

Browse all Theses and Dissertations

Commercially available polyethyleneimines varying in molecular weights and viscosities were synthetically modified in order to increase their hydrophobicity when dissolved in water. Used as additives for inkjet industry inks, these polymers have been designed to promote interaction between formulated inks and paper, while increasing the water-fastness of these water-soluble inks once they are dried on bond paper. Waterfastness, the ability of an ink to maintain print integrity once it becomes wet, as well as optical density, solubility, pH, molecular weight, polydispersity and viscosity are amongst the characteristics analyzed. The modifications of these polyethyleneimines (PEis) with alkyl bromides and alkyl epoxides …

A New Reduced Order Model For Solid Oxide Fuel Cells, Suryanarayana Raju Pakalapati

Graduate Theses, Dissertations, and Problem Reports

Fuel cells are one of the promising eco-friendly and efficient electricity generators for future energy infrastructure. Rigorous research has been underway for over a decade to develop fuel cell technology as a viable alternative to the conventional energy sources. Numerical modeling has played a prominent role in such research endeavors. Detailed multi-dimensional models reveal important information regarding the performance of a fuel cell but they are computationally intensive. Relatively simple zero- and one-dimensional models on the other hand average out the details that could be critical. The topic of this dissertation is a new strategy for modeling fuel cells which …

Photoreductive Dissolution Of Ferrihydrite By Methanesulfinic Acid: Evidence Of A Direct Link Between Dimethylsulfide And Iron-Bioavailability, Anne M. Johansen, Jennifer M. Key

All Faculty Scholarship for the College of the Sciences

Within open‐ocean regions where excess macronutrients are present, phytoplankton growth is limited by the bioavailability of iron supplied to these areas primarily within atmospheric aerosols of crustal origin. However, processes that control the abundance of biologically accessible iron in these aerosols are largely unknown. Here we show that dissolution of ferrihydrite, a surrogate iron(oxy)hydroxide phase found in atmospheric waters, is enhanced in the presence of methanesulfinic acid (MSIA, CH₃SO₂H, a dimethylsulfide (DMS) oxidation intermediate) in laboratory irradiation experiments with aqueous suspensions that simulate marine aerosol particles. The increased release of soluble Fe(II) is attributed to a …

Semiclassical Nonadiabatic Dynamics Based On Quantum Trajectories For The O(3P,1D)+H2 System, Sophya Garashchuk, Vitaly A. Rassolov, George C. Schatz

Faculty Publications

The O(³P,¹D)+H₂→OH+H reaction is studied using trajectory dynamics within the approximate quantum potential approach. Calculations of the wave-packet reaction probabilities are performed for four coupled electronic states for total angular momentum J = 0 using a mixed coordinate/polar representation of the wave function. Semiclassical dynamics is based on a single set of trajectories evolving on an effective potential-energy surface and in the presence of the approximate quantum potential. Population functions associated with each trajectory are computed for each electronic state. The effective surface is a linear combination of the electronic states with the contributions …

Bounded Search For De Novo Identification Of Degenerate Cis-Regulatory Elements, Jonathan M. Carlson, Arijit Chakravarty, Radhika S. Khetani, Robert H. Gross

Dartmouth Scholarship

The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential cis-regulatory elements. However, in practice many cis-regulatory elements are highly degenerate, precluding the use of an exhaustive word-counting strategy for their identification. While numerous methods exist for inferring base distributions using a position weight matrix, recent studies suggest that the independence assumptions inherent in the model, as well as the inability to reach a global optimum, limit this approach.

Ionic Liquids In Analytical Chemistry, Jared L. Anderson, Daniel W. Armstrong, Guor-Tzo Wei

Jared L. Anderson

Room-temperature ionic liquids (RTILs), also known as liquid organic, molten, or fused salts, are a class of nonmolecular ionic solvents with low melting points. The accepted definition of an RTIL is any salt that has a melting point lower than ambient temperature (1). However, “ionic liquid” (IL) is often applied to any compound that has a melting point <100 °C. Most common RTILs are composed of unsymmetrically substituted nitrogen-containing cations (e.g., imidazole, pyrrolidine, pyridine) with inorganic anions (e.g., Cl–, PF6 –, BF4 –). ILs are also interesting because of their other useful and intriguing physicochemical properties. Wilkes et al. first reported ambient-temperature ILs based on the 1-alkyl-3-methylimidazolium cation in 1982 (2). Since then, many ILs containing a variety of cations and anions of different sizes have been synthesized to provide specific characteristics.

Psd-Project Sequence Database, Matthew Kayala, Akhila Kambhampati, Stephanie Forschner, Bethany D. Jenkins

Bioinformatics Software Design Projects

1. Introduction

The sequencing of nucleic acids and the subsequent analysis of their encoded the genes and proteins has revolutionized biological sciences and allowed for the determination of evolutionary origins and biochemical potential of organisms. While the technology to determine molecular sequence data has become extremely powerful in terms of both automation and thoughput, sequence analysis technology has lagged behind, unable to efficiently keep up with the vast amount of sequence data being generated both in individual labs and by researchers worldwide. The foundation of robust sequence analysis is dependent on the building and maintaining of project sequence databases (PSD) …

New Forensic Courses Separate Fact From Fiction, Rebecca Welzenbach '07

Illinois Wesleyan University Magazine, 2002-2017

As shows like CSI capture the public’s imagination, IWU students learn the hard science behind a rising field.

Revisiting The Legal Link Between Genetics And Crime, Deborah W. Denno

Law and Contemporary Problems

In 1994, convicted murderer Stephen Mobley became a cause celebre when he appealed his death sentence before the Georgia Supreme Court in the case of Mobley v. State. Denno describes the potential implications arising from the high-profile case of Stephen Mobley. He sought to introduce a then-cutting-edge theory that violence could be based on a genetic or neurochemical abnormality as mitigating evidence during capital sentencing.

Abstracts Of Papers, 84th Annual Meeting Of The Virginia Academy Of Science

Virginia Journal of Science

Full abstracts of papers for the 84th Annual Meeting of the Virginia Academy of Science, May 25-26, 2006, Virginia Polytechnic Institute and State University, Blacksburg, VA

Synthesis Of Aspernigrin A, Erica Joerger

Undergraduate Theses and Capstone Projects

Aspernigrin A is a compound correlated with inhibiting the growth of cancer cells in the colon. A five-step synthesis was designed for aspernigrin A, projected to yield four intermediates and the final product. The intermediates were analyzed by high field 1HNMR and FT-IR spectroscopy before proceeding to the next step. A model pyridone ring system was successfully prepared from a commercially available pyrone precursor in two steps. These results provide a proof of concept that the synthetic scheme should successfully yield the natural product.

A Critical Analysis Risk Assessment: Food Irradiation: Pro Or Con?, Lisa Bonomo

ESSAI

No abstract provided.

Chem Club Is In Its Element, University Relations

Campus News Archive

If your only idea of chemistry is a laboratory filled with test tubes, Bunsen burners and teachers dressed in lab coats, UMM Chem Club students may change your mind.