Digital Commons Network^™

Patterns Of The Use And Perception Of Cannabis Among College Students In Tennessee, Jayla Ruffus-Milner

Electronic Theses and Dissertations

Cannabis has been historically difficult to research due to its federal scheduling. However, as legalization of cannabis medically, recreationally, or both in states across the country has increased, so has the need to address the research gaps that persist. The purpose of this study was to explore the patterns of cannabis use and perceptions of college students in Tennessee, which encompass a demographic of mainly young adults who are typically associated with high usage patterns. The study uses quantitative data collected from an online survey sent to a university in East Tennessee to evaluate associations between students’ age, gender, race/ethnicity, …

Educating Anesthesia Providers On The Physiological Effects And Anesthesia Implications Of Cannabis, Carmel Loud

Doctor of Nursing Practice Projects

In the U.S., currently 37 states have legalized cannabis for medicinal use prescribed by qualified medical professionals (National Conference of State Legislatures [NCSL], 2022). In 2012, the legalization of recreational cannabis began; as of 2022, 19 states have legalized the recreational use of marijuana (NCSL, 2022). This project aimed to optimize care for patients using cannabis by increasing anesthesia provider knowledge about cannabis. The project's aim was accomplished through a thorough review of the current medical literature and implementation of education to anesthesia providers about the physiological effects and anesthesia implications of cannabis. Thirteen CRNAs took a pre- and post-quiz …

Phenology, Olfactory Response, And Tritrophic Interactions Of Helicoverpa Zea And Chloridea Virescens On Hemp, Cannabis Sativa, Julian B. Cosner

Doctoral Dissertations

Industrial hemp, Cannabis sativa L., production has been revived in the United States following its legalization through the Agricultural Improvement Act of 2018 (a.k.a. 2018 Farm Bill). The corn earworm, Helicoverpa zea (Boddie), has been considered one of the most harmful insect pests in outdoor hemp production as larvae feed on the marketable grain and inflorescences where cannabinoid concentrations are highest. However, in Tennessee, a Heliothine complex, including corn earworm and the tobacco budworm, Chloridea virescens (F.), occurs on hemp. To investigate the seasonal incidence of these hemp pests, larvae were collected from hemp grown in different regions of Tennessee …

Nutrient Management Of Cannabis In Controlled Environments, Julie A. Hershkowitz

All Graduate Theses and Dissertations, Fall 2023 to Present

Cannabis has been cultivated for millennia as a multipurpose crop for food, fiber, and medicine. Secondary metabolites called cannabinoids, including cannabidiol (CBD) and the psychoactive Δ-9 tetrahydrocannabinol (Δ-9 THC), are responsible for the medicinal properties of cannabis. The intoxicating nature of THC resulted in legislation prohibiting the possession and production of cannabis within the United States during the 20^th century. As a result, research programs on cannabis production were halted at most institutions. In recent years, cannabis production has become widespread within the US as a result of increasing legalization. However, modern cannabis production nutrient management programs often include …

Individual Differences In Cannabis Use Disorder With Implications For Endocannabinoid Modulation In Therapeutics Development, Erin Martin

MUSC Theses and Dissertations

Cannabis use disorder (CUD) is increasingly prevalent in the United States, but there is no effective pharmacological means to treat it. The endocannabinoid (eCB) system has emerged as a candidate therapeutic target demonstrating some evidence of efficacy in treating CUD. However, clinical trials evaluating eCB-modulating therapeutics have historically undervalued individual differences that could contribute to variation in treatment outcome (e.g. sex, comorbid psychiatric illness). To address this gap in the literature, the present set of studies (a) compared plasma eCB tone in groups underrepresented in treatment trials for CUD (females, individuals with comorbid major depressive disorder; MDD/CUD) with males or …

Detailing The Effects Of Cannabidiol On Exosome Release In Ewing’S Sarcoma, Bennett Hasley

Theses

Ewing’s sarcoma (ES) is a highly aggressive pediatric cancer found within bone that carries a low five-year survival rate within its patients. This is due, in part, to the cancer’s high malignancy properties as well as the development of resistance to the chemotherapies used to combat this cancer. This project aims to determine if cannabidiol (CBD) has an effect on either exosome release or the protein, signal transducer and activator of transcription 3 (STAT3) within ES cells. Exosomes are vesicles that can carry proteins and other signaling molecules which are released by the cell and allow for cell-to-cell communication. Within …

A Meta-Analysis Of Cannabis Research: Is There Evidence Of Lasting Neurocognitive Effects?, Mark J. Crisafulli

Graduate Thesis and Dissertation 2023-2024

Cannabis use in the United States has generally increased over the past decade as more States have legalized recreational use. In conjunction with changes to the chemical makeup, which has made available cannabis more potent, the long-term effects experienced by cannabis users may have changed, and more individuals may be effected. The current study replicated the methods used in Schreiner & Dunn (2012) and Grant et al. (2003) to conduct a meta-analysis examining the neurocognitive effects of cannabis after abstinence lasting a period of at least 25 days. Previous research has found mixed results, with some studies finding significant differences …

The Role Of Medical Cannabis Use In Pain, Sleep, And Mental Health Outcomes Among Older Adults, Madison H. Maynard

Graduate Thesis and Dissertation 2023-2024

Older adults represent the fastest growing demographic of cannabis users, and they endorse cannabis use for a variety of reasons including modulation of chronic pain, mental health symptoms, and sleep concerns. Despite escalating patterns of use, current evidence leaves questions of efficacy unanswered among these groups of users. Goals of the present study were to examine the role of medicinal cannabis within subjects at the daily level on the interrelated symptoms of depression, anxiety, sleep, and pain. A final sample of 106 medical cannabis users were recruited nationwide, ranging from 55 to 74 years of age (66.67% female, 82.86% white). …

Neural Hyperactivity During Value-Based Decision-Making In People With Daily/Near Daily Cannabis Use, Miranda Ramirez

Theses and Dissertations--Psychology

Value-based decision-making involves the coordinated effort of multiple brain regions to guide future choices based on past experiences. These processes are disrupted in cannabis use disorder, where individuals continue to use cannabis despite negative consequences. Reinforcement learning (RL) paradigms can be used to capture changes in the value of available options and may inform how the brain is impacted by frequent cannabis use. This study combined fMRI with behavioral modeling of probabilistic choice task data to compare value-based choices between young adults reporting daily/near daily cannabis use (CAN) and controls (CTRL). Participants selected one of two options reinforced ($0.25) at …

The Effects Of Full Spectrum Hemp Oil On Extinction Of Stress Enhanced Fear Learning In A Rodent Model Of Ptsd, Tiphanie Chanel

Psychology ETDs

There are only 2 FDA-approved treatments for Post-Traumatic Stress Disorder (PTSD) despite the overwhelming evidence of the need for safer and more effective treatments. For example, roughly 50% of treatment seeking patients with PTSD experience relief from conventional pharmaceutical medications and only one third experience full remission. The Cannabis plant is a promising novel treatment for PTSD for several reasons. The endocannabinoid system plays a role in stress, emotion, cognition, suicidal phenotypes, fear memory consolidation, retrieval and reconsolidation and extinction. Cannabidiol (CBD), one of the most widely studied phytocannabinoids found in the Cannabis plant, has both anxiolytic and antidepressant qualities. …

A Phenomenological Inquiry Into Healthcare Professionals Who Are Experts In Cannabinoid Therapy And The Endocannabinoid System (Ecs), Courtney Collins

Electronic Theses and Dissertations

Cannabis is a prevalent alternative treatment for many symptoms and conditions given its medicinal qualities and few side effects. As legalization for both medical and recreational purposes continue to develop quickly across the United States of America, there is serious discrepancy between legalization and clinical research. Clinical data is difficult since the U.S. federal government still classifies cannabis as a Drug Enforcement Agency (DEA) Schedule I drug with no clearly established medical value. This lag in evidence-base data has affected cannabinoid therapy and endocannabinoid system education (ECS) for healthcare professionals. There are gaps in medical school and continuing medical education …

Medical Marijuana In Mississippi: A Journalistic View Of Physician Opinions And Patient Education, Michael Pitts

Honors Theses

Medical Marijuana in Mississippi: A Journalistic View of Physician Opinions and Patient Education is an in-depth investigative journalism project examining aspects of the Mississippi Medical Cannabis Program. Specific areas of interest were Mississippi physician opinions on the use medical marijuana and their views on the application of the state’s program as well as an examination into how patients are receiving education on medical marijuana. This project involved interviews of healthcare providers, dispensary staff, and patients, in addition to background research that was used to formulate interview questions, determine areas of interest and add necessary context. This project occurred during the …

The Effect Of Cannabinoids And Terpenes On The Activation Of Hmc3 Microglial Cells, Mohamed Marzouk

Honors Theses

Life expectancies of people living with HIV have significantly lengthened due to the availability of antiretroviral therapies. Despite their ability to increase survival, these treatments do not “cure” HIV, nor do the stop the onset of neurological symptoms associated with infection, termed neuroHIV. NeuroHIV describes a myriad of neurological impairments including mood disorders (depression and anxiety), cognitive impairment, neuropathic pain, and motor disinhibition that reduce quality of life for people living with HIV. Mechanistically, the neurological impairments may involve actions of neurotoxic proteins directly produced by the virus. One of these proteins that has been well-characterized is the HIV trans …

Medical Cannabis In Mississippi: Practitioner Education And Continuing Research, Andrea Cleveland

Honors Theses

Use of medical cannabis in Mississippi was legalized in February 2022 following many years of cannabis research at the University of Mississippi. Issues immediately became apparent, beginning with the lack of education about medical cannabis among providers. A 2017 study showed that the majority of physicians are not exposed to information about medical cannabis despite its legalization in 37 states. Another issue with Mississippi’s medical cannabis program is the cost of the product itself. The most effective way to decrease spending on medication is for patients to have access to medication that is guaranteed to work. Further research on cannabis …

Cannabis Consumption On A College Campus: Mental And Behavioral Health, Joseph Benjamin Gareis

Undergraduate Honors Thesis Collection

Background: Societal views and many state and federal laws regarding cannabis are evolving. Cannabis use is increasing, with the highest prevalence among young adults ages 18-25. Both the 2021 National Survey of Drug Use and Health (NSDUH) and the 2022 National College Health Assessment survey found that ~35% of young adults used cannabis within the last year. Methods: Students, faculty, and staff at a small, private university in Indiana were surveyed regarding cannabis use and mental/behavioral health. Participants were recruited via university list serves and social media. The anonymous confidential survey was administered electronically via Qualtrics between December 9, 2022 …

Education For Oncology Providers On The Benefits, Uses, And Local Resources Of Medical Marijuana, Jessica Landrum, Brianna Linsley

Doctor of Nursing Practice Projects

Medical marijuana is used to reduce symptoms of medical conditions including cancer. Medical marijuana can increase quality of life among patients with cancer by treating symptoms such as pain, nausea, and vomiting. For providers to care for this population, they must understand the implications for treatment, pharmacological properties, and legal issues related to medical marijuana use.

Nurse practitioners at a cancer clinic in rural Illinois were unable to prescribe medical marijuana because they did not have the necessary knowledge about medical marijuana. The nurse practitioners at the clinic were requesting a “toolbox” containing medical marijuana resources such as uses for …

Better Budtender Training, Vincent Mcdonald Castillo

Capstone Projects and Master's Theses

A survey conducted by the cannabis education program in the Monterey County Health Department (MCHD) concluded that around 57% of users in the county do not feel educated enough in the subject to form their own educated opinions about cannabis use (Cannabis Education Survey 2022). The MCHD decided to address this concern by collaborating with local dispensaries to provide an educational course in video form for budtenders. This video provides factual information on consumption methods, how differently they may affect people and the recommended time to wait before operating a vehicle. Following this education, consumers of cannabis will have reliable …

A Cross Sectional Comparison Of The Mental Health, Sleep, And Anaerobic Power Of Cannabis Users, Cannabidiol Users, And Non Users, Taylor Tamanaha

Master's Theses

The purpose of this study was to determine whether there are differences among groups of individuals who regularly use cannabis, cannabidiol (CBD), or who are non-users with respect to mental health, sleep, and anaerobic power measures. A total of 24 participants (21 males and 3 females) were recruited and placed into groups based on their regular cannabis/CBD or non-cannabis/CBD use. The cannabis user group was using cannabis at least three times per week for the past 8 weeks (CA; n=8), the CBD user group was using CBD at least three times per week for the past 8 weeks (CB; n=8), …

Effects Of Cannabichromene On Pain And Neuroinflammation In Hiv-1 Tat Transgenic Mice, Sydney Wheeler

Honors Theses

HIV-1 TransActivator of Transcription (Tat) is a vital regulatory protein involved in HIV replication and implicated in development of HIV-associated pain and neurocognitive deficits. Tat is thought to contribute to these pathologies through proinflammatory pathways. Developing mechanisms to curb Tat-mediated inflammation is a key step in improving the quality of life of those living with HIV. Both recreational and medicinal cannabis use is prevalent among many people living with HIV; given this prevalence and the perceived anti-inflammatory benefits of cannabis use, it is important to investigate how chemical constituents of cannabis may impact HIV. In the present study, the effects …

Association Between Arkansas Cannabis Program Implentation And Drug Overdoses, Alex Hooper

MUSC Theses and Dissertations

Overdose rates have been on the rise in the United States. In 2018 Arkansas launched its medical cannabis program. The effects of cannabis are still not widely known due to limited research and legislation. Utilizing state issued reports, we examined if a state medical cannabis program had any impact on overdose rates between 2018 and 2020. Data was examined from the Arkansas Prescription Drug Monitoring Program and the Arkansas Medical Marijuana program to determine if a pattern could be recognized on the impact of state medical cannabis programs. Data was examined at a county level to determine if any change …

Cannabis Use Across The Menstrual Cycle: The Impact Of Negative Affect And Coping Motives, Paige Morris

LSU Master's Theses

Women appear to use more cannabis during the premenstrual and menstrual phases of the menstrual cycle, presumably because women use cannabis to manage increases in negative affect associated with these phases. Yet little work has tested this hypothesis or examined individual difference variables associated with greater coping-motivated cannabis use. The current study tested whether state negative affect interacts with coping motives to predict greater cannabis use during the premenstrual and/or menstrual phases and whether trait anxiety or difficulties with emotion regulation moderate these relations. Female undergraduate students with regular monthly menstrual cycles and who were not using hormonal contraceptives ( …

Examining The Relationship Between Outcome Expectancies And Anxiety Severity In Patients Using Medical Marijuana, Paulina Syracuse

PCOM Psychology Dissertations

Many states have legalized marijuana for medical and recreational use despite it being classified as a Schedule I controlled substance. Although research regarding its efficacy is limited, one of the most common medical marijuana referral reasons is anxiety and patients often report experiencing reductions in anxiety. Many patients have beliefs about the effects of medical marijuana, called outcome expectancies, which may differ based on previous recreational marijuana use. These beliefs may influence anxiety outcomes, but this relationship is still unclear. The purpose of this study is to examine the relationship between patients’ medical marijuana outcome expectancies, previous recreational marijuana use, …

Benefits Of Medical Thc For Neurological Disorders In The U.S., Andrew Lester, Alexandria Gartin

Theses, Dissertations and Capstones

Introduction: The introduction of THC into the medical field has allowed medical professionals to offer a new treatment option to aid in their patients treatment plan by decreasing their symptoms of side effects of other medications used for their conditions.

Methodology: This study utilized a literature review. Five databases were used to collect 116 total sources. These sources were reviewed and reduced to 33 sources that were used in the written research. Of these, 16 sources were used in the results section.

Purpose of the Study: The purpose of this research was to analyze the prescription use of …

Habitat Selection And Habitat Use Of Gray Foxes (Urocyon Cinereoargenteus) On Trespass Cannabis Grows., Haley-Marie R. Jones

Cal Poly Humboldt theses and projects

Trespass cannabis grow sites, otherwise known as illegal cultivation sites on public lands, are extremely hazardous to the environment and can severely impact wildlife movement and behavior. Trespass grow sites are dangerous to wildlife as they negatively impact the quality of habitat and wildlife behavior through habitat modification, pesticide use, discarding of trash, and poaching on national forests. I researched gray fox habitat selection and habitat use at six different grow sites in the Klamath National Forest and Shasta-Trinity National Forest in northwestern California. I deployed GPS collars on three gray foxes at two of those grow sites and three …

Impulsivity Facets Associated With Co-Use And Consequences Of Alcohol And Cannabis Via Perceived Norms, Melissa C. Rothstein

Open Access Master's Theses

Co-use of alcohol and cannabis, or use of these substances simultaneously such that their effects overlap, is prevalent and growing. Compared to alcohol-only use, co-use of alcohol and cannabis is associated with greater negative consequences, such as heavier drinking, more cognitive issues, and risky behavior. Impulsivity (i.e., tendency toward rash action without consideration of consequences) and perceived norms (i.e., a social influence by which individuals adjust their behavior to that of their peers) are two factors related to increased substance use among young adults, but few studies have examined their role in co-use behaviors. Consequently, the purpose of this study …

Impact Of Telehealth Versus Traditional Visits On Pain Management Patients Utilizing Medical Cannabis During The Covid-19 Pandemic, Todd Pankratz

Walden Dissertations and Doctoral Studies

AbstractAlternatives to traditional office visits have become a necessity with the recent COVID-19 outbreak, resulting in an unmatched surge in telehealth adoption. The present study was an investigation of the impact of telehealth versus traditional office visits in medical cannabis clinics treating patients for chronic pain. With 50,000,000 American adults experiencing pain and over 750,000 overdoses attributed to opioid usage, collecting research-driven evidence to increase the availability of safe, effective, and nonopioid treatment options will create positive social change. The Donabedian model was applied to measure the quality of care, focusing on structure (cannabis clinics), process (telehealth vs. traditional office …

Marijuana Cultivation Laws And Admissions For Cannabis Use Disorder In Us Substance Abuse Treatment Facilities, Nada Al-Rubaiee

Walden Dissertations and Doctoral Studies

With approximately 4.4 million Americans addicted to cannabis, it is considered a dominant non-medical drug that is common in the US. The purpose of this study was to investigate the possible contribution of the state laws that allow the cultivation of marijuana to Marijuana Medical (MM) program cardholders on cannabis addiction. This study was conducted to address the issue of the increase in demand for cannabis-related admissions that contribute to an upsurge in the unmet treatment needs. The study is founded on the Ecological Models proposed by Urie. The key research question explored the association between state laws that allow …

Closing The Knowledge Gap For Advanced Practice Nurses On Medical Cannabis, Regina Bernice Askew-Gibbs

Walden Dissertations and Doctoral Studies

AbstractSince cannabis, also called marijuana, has been decriminalized or legalized as a prescription for medical purposes, more patients are using cannabis recreationally for medical purposes or as a holistic therapeutic approach in contrast to Western medicine. With increased use among patients, it has become important for the advanced practice nurse (APN) to have a basic knowledge of the therapeutic benefits of marijuana. The goal of this DNP project was to supply APNs with education on marijuana and cannabis to prevent poor patient assessment and education. Pre-and posttest data from 6 participants who work at a medical, ambulatory clinical site, were …

Examining The Relationship Between Undergraduate Female Students Marijuana Use And Gpas, Darrel E. Hicks

Walden Dissertations and Doctoral Studies

Marijuana use has been linked to poor undergraduate student academic performance, yet cannabis continues to be the substance most often used by college students. The purpose of the current research was to add to the limited body of literature about the relationship between female undergraduate marijuana use and lower GPAs. The study explored how marijuana use impacted the GPAs of undergraduate African American females. The research question addressed whether a significant relationship exists between marijuana use and lower GPAs for this population. Complex adaptive systems theory was the lens used to better understand the phenomenon during a time of rapid …

Impact Of Telehealth Versus Traditional Visits On Pain Management Patients Utilizing Medical Cannabis During The Covid-19 Pandemic, Todd Pankratz

Walden Dissertations and Doctoral Studies

AbstractAlternatives to traditional office visits have become a necessity with the recent COVID-19 outbreak, resulting in an unmatched surge in telehealth adoption. The present study was an investigation of the impact of telehealth versus traditional office visits in medical cannabis clinics treating patients for chronic pain. With 50,000,000 American adults experiencing pain and over 750,000 overdoses attributed to opioid usage, collecting research-driven evidence to increase the availability of safe, effective, and nonopioid treatment options will create positive social change. The Donabedian model was applied to measure the quality of care, focusing on structure (cannabis clinics), process (telehealth vs. traditional office …