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An Analysis Of Socio-Economic Consequences Of Cancer In Nepal, Soumi Roy Chowdhury
An Analysis Of Socio-Economic Consequences Of Cancer In Nepal, Soumi Roy Chowdhury
Economics ETDs
This dissertation investigates the socio-economic burden of cancer patients using a primary survey in Nepal. Given the low uptake rate of cancer screening facilities in developing countries, my study covers three important issues: the need of information dissemination on cancer prevention among asymptomatic individuals, the emotional stress of cancer patients in relation to a control group of patients, and the severity of economic burden due to premature cancer related deaths measured at the national and individual levels. In developing countries with low level of information and awareness, it is difficult to communicate the importance of cancer preventative measures to the …
Mathematical Modeling Of Nanoparticle Biodistribution, Prashant Dogra
Mathematical Modeling Of Nanoparticle Biodistribution, Prashant Dogra
Biomedical Sciences ETDs
The prospects of nanoparticle-based drug delivery and imaging have been hindered by insufficient understanding of the effects of nanoparticle physicochemical properties on their in vivo disposition. Here, we present an integrative mathematical modeling and in vivo imaging approach to quantify the relationship between nanoparticle physicochemical properties, namely, size, surface charge, and surface chemistry, on their in vivo disposition kinetics in healthy rats. We developed simple master equations in closed-form to accurately represent the time-dependent concentration of nanoparticles in different regions of the body and obtain functional relationships for predictive purpose to support rational design of nanomedicine. We further used …