Digital Commons Network^™

Protein Kinase M Zeta-Mediated Ltp Maintenance In The Non-Human Primate Hippocampus: A Role For Stress And Serotonergic Signaling In Affective Processing, Sasha L. Fulton

Theses and Dissertations

Early-Life Stress (ELS) is associated with vulnerability to mood disorder, but it’s not well understood how ELS contributes to deficits in cognitive function. Atypical PKMzeta is critical for LTP maintenance and memory. The current study aims to characterize the ELS phenotype with respect to this key marker of hippocampal LTP.

“In Black And White, I’M A Piece Of Trash:” Abuse, Depression, And Women's Pathways To Prison, Alexa Adamo Valverde

Women's, Gender, and Sexuality Studies Theses

Women’s lived experiences of abuse and depression are examined within the context of gendered and racialized pathways to incarceration among 403 women randomly selected from a diagnostic unit in a state prison. This study utilizes feminist action research and community psychological methods to understand what factors predict incarcerated women’s placement on the mental health caseload and provides quantitative support for the pathways theoretical framework. Findings indicate that, among the sample, the prevalence of abuse experiences prior to incarceration exceeded 90%, prevalence of mental health problems exceeded 70%, and less than 35% were receiving mental health care. Being Caucasian, experiencing depression …

Mindfulness In Education: A Literary Analysis And Program Proposal, Halle Graham

Honors Theses

The purpose of this work is to understand the potential impact of introducing mindfulness meditation and other contemplative practices to the United States Public Education System. Broken into two main components, the first section of this work is a literary analysis. Relevant studies on mental health in children and adolescents are analyzed in order to understand the state of mental wellbeing among the sample group. Research studies on integrating mindfulness into institutions (public and private schools, children’s summer camps) are also evaluated in order to understand the applications of mindfulness practices in terms of children and adolescents. Overall, the research …

Evidence Based Protocol: Improving Depression Assessments In Primary Care, Katherine E. Hoffhines

Master's Projects

Depression is a destructive condition that can have a profoundly negative impact on quality of life, wellbeing, and health (Thase, Stowell, Berry, Mencia & Blum, 2014). Worldwide, depression is the leading cause of medical disability costing the health care system over $210 billion annually (World Health Organization, 2014; Greenberg, Fournier, Sisitsky, Pike & Kessler, 2015). The World Health Organization (2016) estimates depression affects 350 million people of all ages globally. One and three adults in the U.S. will experience a major depressive episode during their lifetime (Kessler, Petukhova, Sampson, Zaslavsky & Wittchen, 2012; Rubin, Ciechanowski, Egede, Lin & Lustman, 2004). …

Interactions Between Stress-Induced Inflammation, Glycogen Synthase Kinase 3 (Gsk3), And Depression, Yuyan Cheng

Open Access Dissertations

Major depressive disorder is a prevalent disease that is inadequately treated with available interventions, and recovery is difficult, particularly in patients refractory to antidepressant treatments. Studying the learned helplessness depression model in mice, we examined mechanisms regulating its initiation and regulating its reversibility. Stress increases susceptibility to depression in patients and rodent models, and depression is associated with aberrant activation of inflammation. We found multiple inflammatory cytokines were increased in mouse plasma and hippocampus after a paradigm of inescapable foot shock stress that causes learned helplessness. A 24 hr prior pre-conditioning stress accelerated the rate of stress-induced plasma and hippocampal …

The Effect Of Melatonin Upon Post-Acute Withdrawal Among Males In A Residential Treatment Program (M-Paws): A Randomized, Double-Blind, Placebo Controlled Trial, Corry D. Bondi

Electronic Theses and Dissertations

The study goal was to assess melatonin as an adjuvant treatment along with current pharmaco- and behavioral therapy for 28 days on weekly self-reported severity of anxiety, depression, stress, and sleep complaints as well as how sleep is affecting daily life in a sample of males in recovery from chemical dependency at a single, residential treatment site, Salvation Army Harbor Light Center in Pittsburgh, PA. This study was a single-center, randomized, double-blind, placebo-controlled, parallel group trial of 28 days. Participants were randomized to melatonin (5 mg) or placebo and instructed to administer the intervention nightly at bedtime. Primary self-reported outcome …

Treatment Preferences And Outcome In A Randomized Controlled Trial For Depression Comparing Supportive-Expressive Therapy To Medication And Pill Placebo, Sophia Elsie Winter

Doctoral Dissertations

Previous research regarding the relationship between patient treatment preferences on outcome has been equivocal, with some studies finding a significant relationship between preference match and outcome, and others finding no such evidence. This study examines the effect of patient treatment preference match on outcome using data from a previously published randomized controlled trial comparing supportive-expressive therapy (SET), to antidepressant medication plus clinical management, and to pill-placebo plus clinical management. The original study included 156 participants receiving treatment at the Center for Psychotherapy research at the University of Pennsylvania in Philadelphia, PA. This study is the first to examine the relationship …

The Effect Of Film Score On Emotion And Self-Talk, Angela Nanette Davis

Open Access Theses

The purpose of this study was to first assess the effect of film score on affect in healthy young adults. Second, the study examined the subsequent effect of mood change on self-talk in relation to a stressor. Participants were 131 University of Miami undergraduate students between the ages of 18 and 24 who were not musicians, recruited from all departments of study, excluding the Frost School of Music. Each participant completed a mood assessment, resulting in both a PASS (positive) and Dysphoria (negative) score, prior to one of three mood induction conditions: negative film score, positive film score, and control. …

Depression Scores In Males And Females With Copd, Cynthia Southers

Nursing Theses and Capstone Projects

The purpose of this study was to determine the effect of participation in a pulmonary rehabilitation (PR) program on depressions scores in persons with COPD and if there is a difference between males and females in depression scores prior to and following participation in a pulmonary rehabilitation program. The literature review supported multiple factors on how participating in a pulmonary rehabilitation program can have a positive effect on depression scores. The study utilized a descriptive design with a retrospective chart review. The quantitative descriptive design identified variables and examined the differences in males and females with COPD using pre- and …

The Effectiveness Of Animal Assisted Activity And Animal Assisted Therapy In Reducing Symptoms Of Depression, Alexis J. Hauser

Counselor Education Capstones

This paper reviews the use of Animal Assisted Activity (AAA) and Animal Assisted Therapy (AAT) to effectively treat individuals experiencing symptoms of depression. This paper discusses the symptoms of depression, the process and techniques of AAA and AAT, and the effectiveness of AAA and AAT in reducing depressive symptoms. It also describes the differences between AAA and AAT and how these techniques can be used individually or in combination with more traditional forms of treatment for depression. An extensive review of literature is provided in this paper with the final section discussing limitations of research and suggestions for future research …

Behavioral Activation Therapy In Treating Depression, Brian Strauss

Counselor Education Capstones

Depression is a prevalent psychological disorder worldwide, and a search for effective treatments—particularly for clients with minimal accessibility to therapy—has been popularized in the mental health community in the last half-century. Behavioral therapy has become very popular for treating depression, most notably by changing maladaptive behaviors and habits into effective behaviors (Gelder, Marks, & Wolff, 1967). Activation Therapy has come to the forefront of behavioral therapy, making use of activity scheduling, problem solving, selfmonitoring, goal setting, and empowering clients to take charge of their treatment. Through restructuring behaviors, habits, reducing brain activity needed for productive thoughts, and alleviating rumination, Activation …

Examining The Associations Between Depressive Symptoms, Body Mass Index, And Physical Activity Self-Efficacy In African American Mother-Child Dyads, Y'Esha Vonyae Williams

Theses and Dissertations (ETD)

In recent decades the prevalence of childhood and adult depression and obesity has increased worldwide. Multiple factors influence the onset of both depression and obesity. Individual manifestations of depressive symptomatology and health-related problems associated with obesity vary; however, genetics and environmental and psychological factors have been implicated as correlates. Consequently, both disorders can ultimately interfere with individuals’ activities of daily living and decrease their quality of life. African American women are known to have a higher prevalence of obesity and more severe depressive symptoms in comparison to Caucasian women. Likewise, African American children are more obese and experience many factors …

The Prospective Associations Of Stress, Depression, And Social Support With Smoking Cessation And Relapse Among Low-Income Pregnant Women, April Lasha Nellum

Electronic Theses and Dissertations

Maternal smoking is one of the most preventable causes of adverse birth outcomes and poses substantial health risks for both the mother and child. Evidence suggests that increased stress and depression is associated with smoking behaviors, including smoking cessation and smoking relapse. However, few studies have prospectively examined these associations and no studies have examined neighborhood crime, an important stressor for many low-income women, as a predictor of smoking cessation and relapse among this population. The primary objective of this study was to examine the prospective associations between stress, depression, and pre- and postpartum smoking cessation, and postpartum relapse among …

Experiential Avoidance, Depression, And Satisfaction With Life: The Moderational Role Of Regulatory Emotional Self-Efficacy, James E. Sweeney

Electronic Theses and Dissertations

Experiential Avoidance (a process of not accepting internal experiences and rigidly attempting to alter the form, frequency, or intensity of these experiences) has been related to a variety of negative outcomes, including heightened depression and decreased satisfaction with life. Because of this, factors that may buffer or account for the relationship between experiential avoidance and these outcomes should be examined. Regulatory emotional self-efficacy may be one important factor that moderates the relationship between experiential avoidance and outcomes, yet no studies have examined this possibility. The purpose of this study was to examine whether regulatory emotional self-efficacy and experiential avoidance interacted …

Levels Of Distress Among Women Veterans Attending A Women’S Health Specialty Clinic In The Va Healthcare System, Debbie T. Devine

USF Tampa Graduate Theses and Dissertations

Currently, between 21.9 and 23 million veterans have served in the United States armed forces. Of those, 2 million are women, and of those, only 6.5% use the Veterans Health Administration system. These females often suffer from physical and mental health disorders, and overall impaired quality of life (QOL), rendering their healthcare needs complex. Seeking, and providing care in this specialty area may become overwhelming not only for the women seeking the care, but also for healthcare systems that are unfamiliar with the specific needs of this population.

A retrospective medical records review was completed of 51 female veterans between …

Brooding, Avoidance, And Suppression As Mechanisms Linking Shame-Proneness With Depressive Symptoms, Melissa Rose Hudson

Clinical Psychology Dissertations

Depression is a significant mental health concern. Cognitive-affective models of depression identify that negative emotions and cognitive strategies for responding to negative emotions contribute to the development and maintenance of depressive symptoms. Shame has been identified as a problematic negative emotion and is associated with multiple mental health concerns including depression. Research has begun to examine cognitive emotion regulation strategies individuals use when experiencing shame and how these contribute to depressive symptoms. This study examined three strategies jointly (avoidance, brooding, and suppression) in a three-part prospective design. In a sample of 137 young adults, three hypotheses were tested. Participants ranged …

A Behavioral Economic Analysis Of Obesity Among College Women, Holly Ann Keating

Electronic Theses and Dissertations

Overweight and obesity are particularly saient concerns for adolescents and young adults, the age group with the greatest risk of weight gain each year. The present study examined differences in behavioral economic measures of food reinforcement and delay discounting among normal weight women compared to overweight and obese adult women. Effects of symptoms of depression and ethnicity were also examined. Young adult women were given a variety of questionnaires. The current study hypothesized that overweight and obese women would rate food images as being more pleasant, discount money more steeply, have higher food-related reinforcement, and higher demand for food. Overweight …

Depression’S Connection To Self-Harming Behavior In Adolescents, Michael T. Hendrick

Education Masters

Self-harming behavior amongst adolescents has increased in prevalence throughout America. There is a direct connection between depression and self-harming behaviors in adolescent students. The most common reasons why adolescents participate in self-injury are as a coping mechanism, a means of relief, for the regulation of feelings, self-punishment, attention seeking and sensation seeking. There is often a link between depressive symptoms and negative life events or past trauma. Multiple methods of self-harm are often performed by students and may be carried out several times over the course of many months, the techniques used vary greatly. Schools are one of the most …

Deeper Than Roots, Braelyn D. Spencer

All NMU Master's Theses

This collection of essays explores the author’s relationship with home. The author works through family, death, relationships, illness, and growth. The essays consist of an analysis of rooms within a house, the act of burying loved ones, and discovering what it is to move away. These essays aim to mix retellings of everyday events and relationships with deep personal turmoil and the growth that result from it.

Psychological Well-Being And Heart Disease: The Utility Of Mental Health And Management Plans, Jennifer Anne Heath

Theses and Dissertations

This paper explores the correlation between mental health and coronary heart disease (CHD) and the usefulness of including mental health treatment into disease management plans. Consistent with previous research and literature regarding the correlation between CHD and depression, results suggest individuals experiencing CHD experience more symptoms of depression, including feelings of hopelessness and worthlessness. Additionally, individuals with CHD also tend to experience more difficulty with relationships and completing household chores. Individuals who have management plans created by their healthcare providers experience less depressive symptoms than those without management plans. This suggests management plans are crucial in the treatment of mental …

Domains Of Social Support That Predict Bereavement Distress Following Loss: Assessing Need And Satisfaction, Jamison Scott Bottomley

Electronic Theses and Dissertations

Psychological adaptation following homicide loss can prove more challenging for grievers than other types of losses. Although social support can be beneficial in bereavement, research is mixed in terms of identifying whether it serves as a buffer to distress following traumatic loss. In particular, studies have not parsed out specific domains of social support that best predict positive bereavement outcomes. Recruiting a sample of 47 African Americans bereaved by homicide, we examined six types of social support along with the griever's perceived need for or satisfaction with each, and analyzed them in relation to depression, anxiety, complicated grief (CG), and …

Training Affective Flexibility: Effects Of An Affective-Control Training Task On Emotion Regulation, Ashley Marie Malooly

Open Access Dissertations

Studies have shown that cognitive reappraisal is an adaptive emotion regulation strategy. However, individuals differ in how effectively they use reappraisal to regulate negative emotions such as sadness. Cognitive processes, such as those involved in task-switching, inhibition, and attention, may influence how well an individual can utilize cognitive reappraisal. This study sought to investigate whether a cognitive process associated with reappraisal, affective flexibility (AF), could be trained and could improve an individual’s ability to effectively down-regulate sadness. Also examined were potential effects of AF training on symptoms of depression and anxiety, and transfer effects to emotional working memory. Healthy participants …

Bully Victimization, Depression, And The Role Of Protective Factors Among College-Age Lgbtq Students, Theresa E. Bhoopsingh

Dissertations, Theses, and Capstone Projects

This study examined the prevalence and impact (or intensity) of four different bullying-victimization forms (physical, verbal, relational, cyber) as experienced by the LGBTQ college-age population. In addition, this study also investigated LGBTQ college students’ bully victimization experiences and their links to depressive symptomatology. The relationship between self-rated victimization and its impact and depression was also explored. Furthermore, given the potential for protective factors of various types to mitigate the negative impact of bullying, this study investigated social supports from family, friends, and campus to determine the strength of their moderating effects, individually and in combination, for each of the sexual …

Antidepressant And Molecular Responses To Ketamine Linked To Its Inhibition Of Glycogen Synthase Kinase-3 (Gsk3), Steven F. Grieco

Open Access Dissertations

Herein are described two novel outcomes, the up-regulation of 5HTR2C cluster miRNAs and IGF2, as a result of GSK3 inhibition by an antidepressant dose of ketamine that may contribute to the behavioral responses to ketamine.

Feminine Ideology, Relational Self-Concept, And Internalizing Symptoms In Women, Anjali George

Dissertations, Theses, and Capstone Projects

Background: Investigators have theorized that women may experience internalizing disorders such as depression and anxiety more frequently than men in part because of unique socialization processes that women undergo. One aspect of early socialization thought to contribute to women’s propensity for depression and anxiety is the way women are brought up to relate to themselves in relation to others, often placing greater importance on the needs, desires, and value of others, at times at a psychological cost to themselves. This study attempts to elucidate the relationship between gender socialization, relational self-concept, and internalizing symptoms in women.

Methods: Two hundred and …

Intimate Partner Violence And Victim Blaming, Christine A. Weingarten

College of Science and Health Theses and Dissertations

Intimate partner violence (IPV) is highly prevalent within the United States leading to millions of people each year being exposed to violence directly, through involvement in a violent relationship, or indirectly, by witnessing or being close to someone who is in a violent relationship. A common societal response to IPV is victim blaming which attributes fault and responsibility to survivors of abuse. Survivors of IPV report victim blaming as one of the least helpful responses when disclosing to an informal social support. Personal experiences of IPV, either directly or indirectly, can affect levels of victim blame because a person who …

Patterns And Predictors Of Parent-Child Endorsement Discrepancies Among Youth At Chronic-Risk For Depression, Bridget A. Makol

College of Science and Health Theses and Dissertations

Depressive disorders are some of the most common mental health problems among U.S. adolescents, particularly among Latino youth (Merikangas et al., 2010; Twenge & Nolen-Hoeksema, 2002). When parents and their children provide ratings on the presence and severity of the child’s depressive symptoms, their ratings show only low to moderate agreement (Mascendaro et al., 2012). Research has shown that parent–child discrepancies in ratings of youth emotional and behavioral problems are linked to factors such as parental depression and ethnicity. However, discrepancies research has focused primarily on European American families in clinical settings. Subsequently, research has failed to examine discrepancies in …

Psychological Aspects Of Head And Neck Cancer, Katherine Rieke

Theses & Dissertations

Patients with head and neck cancer may be at increased risk for depression diagnosis when compared to other cancer sites, both before and after their cancer diagnosis. Behavioral risk factors for head and neck cancers, including tobacco and alcohol use, may be indicative of depression before cancer diagnosis. Further, head and neck cancers and their treatments can cause serious morbidity among patients, including physical disfigurement and loss of function. Additionally, these cancers are often accompanied by social stigma, personal shame, and guilt. While there is a significant body of research examining depression in this cancer population, there are still several …

The Role Of Electronic Communication Processes Across The College Transition: Relations To The Maintenance And Formation Of Friendships, Psychological Well-Being, And College Adjustment, Patricia E. Dieter

Electronic Theses and Dissertations

Friendship experiences play a vital role in the adjustment of adolescents. Late adolescents transitioning to college negotiate the important developmental tasks of both maintaining close hometown friendships and developing new college friendships. Electronic communication has become a prevalent way to quickly and easily communicate, and friendships that incorporate electronic communication with in-person communication are higher in quality (Baiocco et al., 2011). For some adolescents, however, Internet use becomes excessive and problematic (Ha et al., 2007).

The purpose of this investigation was to examine how individuals use different communication technologies with their existing hometown friends and their newer college friends, and …

Depression And Empathy Predict Emotion-Modulated Startle Reactivity, Alyssa M. Ames

Psychology Theses

Research supports varied patterns of emotion-modulated startle (EMS) reactivity among depressed individuals. The purpose of this study was to examine whether these varied patterns can be explained by depression, empathic tendencies, and emotional stimuli. The EMS paradigm is a well-validated measure of emotion-modulated reactivity in which the magnitude of startle reflexes in reaction to acoustic stimuli are recorded while participants view pleasant, neutral, and negative images (Lang, Bradley, & Cuthbert, 1990). Young adults (N = 120; M_age = 19.54, SD = 1.41; 75% female) completed self-report rating scales of depression symptoms and cognitive and affective empathic tendencies and …