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Molecular Genetics And Functions Of Kaposi's Sarcoma-Associated Herpesvirus Glycoproteins In Viral Entry And Virus-Induced Cell Fusion, Rafael E. Luna
Molecular Genetics And Functions Of Kaposi's Sarcoma-Associated Herpesvirus Glycoproteins In Viral Entry And Virus-Induced Cell Fusion, Rafael E. Luna
LSU Doctoral Dissertations
Kaposi’s sarcoma-associated herpesvirus (KSHV) is considered the etiologic agent of Kaposi’s sarcoma and several lymphoproliferative disorders. Recently, the full-length KSHV genome has been cloned into a bacterial artificial chromosome (BAC) and successfully recovered in 293 cells. The herpesviral glycoproteins are structural components of the KSHV particle and are thought to facilitate virus entry, egress and virus-induced cell fusion. Investigations, described herein, have focused on the genetic manipulation of the KSHV-BAC36 in order to address the role of K8.1 glycoprotein in virus entry and the role of the carboxyl tail a-helices of glycoprotein (gB) in virus-induced cell fusion. In addition, a …
The Relationship Between Social Behavior And Mealtime Behavior Problems In Individuals With Severe And Profound Mental Retardation, David E. Kuhn
The Relationship Between Social Behavior And Mealtime Behavior Problems In Individuals With Severe And Profound Mental Retardation, David E. Kuhn
LSU Doctoral Dissertations
One of the defining features of mental retardation is a problem in adaptive functioning. An area of adaptive skills commonly deficient in this population is social functioning, often characterized as behaviors that provide individuals with the means to interact effectively and appropriately with others. Researchers in this area have generally focused on improving appropriate social behavior and/or decreasing behavioral excesses that interfere with social interactions. Few studies have examined the effects of improving social behavior on collateral behaviors. The current study examined the relationship between social behavior and feeding and mealtime problem behavior in individuals with mental retardation. Individuals across …
Quantification Of Marine Sediment Properties From Planar And Volumetric Pore Geometries, Allen Hagerman Reed
Quantification Of Marine Sediment Properties From Planar And Volumetric Pore Geometries, Allen Hagerman Reed
LSU Doctoral Dissertations
Pore geometry and topology are important determinants of sediment physical properties, such as porosity and permeability. They also influence processes that occur in the sediment, such as acoustic propagation, attenuation, and dispersion, single- and multi-phase fluid flow, and hydrodynamic dispersion. This study uses images to evaluate pore geometry and topology of ooid (subspherical particles) and siliclastic (angular quartz) sand that was collected from the marine environment south of Bimni Bahamas and Ft. Walton Beach, FL, respectively. Image analysis techniques and predictive tools enable insight into the relationships among sediment pore geometry, topology, and physical properties for these differently shaped sands. …
Analysis Of Factors That Affect Responding In A Two-Response Chain In Children With Developmental Disabilities, Stephanie Ann Contrucci Kuhn
Analysis Of Factors That Affect Responding In A Two-Response Chain In Children With Developmental Disabilities, Stephanie Ann Contrucci Kuhn
LSU Doctoral Dissertations
Behaviors that are appropriate, inappropriate, or a combination of both can be linked together in a behavior chain. When the contingencies for one response change (e.g., reinforcement is withheld for the last response in the chain; the last response is reinforced even if it occurs without the other responses in the chain) or the environmental conditions change (e.g., access to the reinforcer is available independent of responding), the other responses in the chain may be affected. Little is known about these types of effects on behavior chains. Several operant processes may disrupt behavior chains. The purpose of this study was …
An Investigation Of The 150-Hour Requirement In Developing Personal Competencies In Accounting Education, Laura Davis Delaune
An Investigation Of The 150-Hour Requirement In Developing Personal Competencies In Accounting Education, Laura Davis Delaune
LSU Doctoral Dissertations
This study investigated if accounting graduates from Louisiana State University, a public institution, perceived that their accounting curriculum enhanced the development of their personal competencies of professional demeanor, problem solving/decision making, interaction, leadership, and communication. A survey mailed to accounting graduates who graduated from Fall 1999 to Spring 2002 was used to gather the data for the study. Responses from graduates with different curricular paths were compared to determine if significant differences existed in their perceptions of the development of their personal competencies. Results revealed that no significant difference exists in the perception of the development of personal competencies among …
The Myth Of Charismatic Leadership And Fantasy Rhetoric Of Crypto-Charismatic Memberships, Shaun Robert Treat
The Myth Of Charismatic Leadership And Fantasy Rhetoric Of Crypto-Charismatic Memberships, Shaun Robert Treat
LSU Doctoral Dissertations
This study will analyze the relationship between myth and the fantasy rhetoric of charismatic leadership by employing Fantasy Theme Analysis to examine the pervasive discourses invoking this enduring folk belief. Fantasies of the Charismatic Superhero are explored within the popular leadership treatises of successful “management gurus” and in our popular culture entertainments. The rhetorical visions of Stephen Covey’s “Principle-Centered Leadership,” Jim Collins’ “Level 5 Leadership,” and Manz and Sims' “SuperLeadership” are examined for their displacement of charismatic leadership in favor of the empowered crypto-charisma of self-leading memberships. Findings suggest “empowerment” rhetorics, like the rhetorical visions championed by many populist “gurus,” …
Integrating A Technology-Enriched Curriculum: Ethno-Case Study, Juliette D. Angers
Integrating A Technology-Enriched Curriculum: Ethno-Case Study, Juliette D. Angers
LSU Doctoral Dissertations
The purpose of this qualitative study was to provide an examination of beliefs, context factors, and practices of exemplary teachers that lead to a technology-enriched curriculum. Three middle school teachers participated. Using both direct and participant observation the Spradley model was followed with three rounds of observations: (1) descriptive, (2) focused, and (3) selective. Interviews were conducted with open-ended questions and documents were collected from the parish website. This research provides: (1) up-to-date information on what and how educational technology is used today; and (2) information which gives other educators an understanding of what beliefs and context factors influence teachers …
A Distributed Quadtree Dictionary Approach To Multi-Resolution Visualization Of Scattered Neutron Data, Rion Dooley
A Distributed Quadtree Dictionary Approach To Multi-Resolution Visualization Of Scattered Neutron Data, Rion Dooley
LSU Doctoral Dissertations
Grid computing is described as dependable, seamless, pervasive access to resources and services, whereas mobile computing allows the movement of people from place to place while staying connected to resources at each location. Mobile grid computing is a new computing paradigm, which joins these two technologies by enabling access to the collection of resources within a user's virtual organization while still maintaining the freedom of mobile computing through a service paradigm. A major problem in virtual organization is needs mismatch, in which one resources requests a service from another resources it is unable to fulfill, since virtual organizations are necessarily …
Botany In Children's Literature: A Content Analysis Of Plant-Centered Children's Picture Books That Have A Plot And Characters, Sheila Lewis Goins
Botany In Children's Literature: A Content Analysis Of Plant-Centered Children's Picture Books That Have A Plot And Characters, Sheila Lewis Goins
LSU Doctoral Dissertations
This content analysis study examined 36 plant-centered children’s science picture books that have a plot and characters published from 1950 to present. Botanical subject matter and learning opportunities offered by these books were analyzed, along with the range and frequency of the National Science Education Standards-consistent and age-appropriate plant science concepts and principles. The science graphics, artistic innovations, and story plot of these books were also examined. Rubrics and research-based recommendations were developed to offer parents, teachers, and librarians assistance in identifying, evaluating, and using such books to help children of ages 4-8 learn about plants and enjoy plant science. …
Turbine Blade Tip Cooling And Heat Transfer, Hasan Nasir
Turbine Blade Tip Cooling And Heat Transfer, Hasan Nasir
LSU Doctoral Dissertations
Turbine blade tip leakage flow from blade pressure side to suction side over the tip surface increases the thermal loading to the blade tip, leading to a high local temperature and thus, is considered one of the primary sources of blade failure. Leakage flow can be reduced by using a recessed or squealer tip blade or by cooling the blade tip to incorporate film cooling. The performance of different recessed tip geometries were investigated and compared with plane tip performance. A transient liquid crystal technique was employed to measure detailed heat transfer coefficient distributions. Coolant injection from holes located on …
Development Of Dynamic Travel Demand Models For Hurricane Evacuation, Haoqiang Fu
Development Of Dynamic Travel Demand Models For Hurricane Evacuation, Haoqiang Fu
LSU Doctoral Dissertations
Little attention has been given to estimating dynamic travel demand in transportation planning in the past. However, when factors influencing travel are changing significantly over time – such as with an approaching hurricane - dynamic demand and the resulting variation in traffic flow on the network become important. In this study, dynamic travel demand models for hurricane evacuation were developed with two methodologies: survival analysis and sequential choice model. Using survival analysis, the time before evacuation from a pending hurricane is modeled with those that do not evacuate considered as censored observations. A Cox proportional hazards regression model with time-dependent …
The Contributions Of Floyd Leslie Sandle To Black Educational Theatre In Louisiana, Ava Marie Brewster-Turner
The Contributions Of Floyd Leslie Sandle To Black Educational Theatre In Louisiana, Ava Marie Brewster-Turner
LSU Doctoral Dissertations
Floyd Leslie Sandle appeared on the theatrical scene in 1938 on the campus of Grambling State University. From his humble beginnings in the segregated town of Magnolia, Mississippi, to Dillard University where his passion for theatre was nurtured by Dr. Sheppard Randolph Edmonds, Sandle made significant strides in the dvelopment of Black Educational Theatre in Louisiana. Through his unique approach of presenting plays to the residents of the rural community of Grambling, Louisiana, Sandle was able to establish a state certified Speech and Drama Department at Grambling State University. He trained students in educational theatre though his lectures, laboratory experiences, …
The Use Of Altrenogest To Control Reproductive Function In Beef Cattle, Clarence Edward Ferguson
The Use Of Altrenogest To Control Reproductive Function In Beef Cattle, Clarence Edward Ferguson
LSU Doctoral Dissertations
There has been great controversy involving progesterone (P4) levels during early pregnancy in cattle. The objectives of these experiments were to determine the effect of an early low dose administration of P4 or altrenogest (ALT) on pregnancy rates in repeat breeder (RPB) females, if an increase in pregnancy rates could result from a direct effect of P4 on the embryo and if ALT could support pregnancy in the absence of a functional CL. Firstly, ALT was evaluated for use as a progestin in cattle by synchronizing estrus in beef heifers. There were no differences in the …
Optimization Of A Skewed Logistic Distribution With Respect To The Kolmogorov-Smirnov Test, James Charles Finney
Optimization Of A Skewed Logistic Distribution With Respect To The Kolmogorov-Smirnov Test, James Charles Finney
LSU Doctoral Dissertations
The four-parameter kappa distribution (Hosking 1994) was analyzed with respect to the various possible shapes of the probability density function. The general form for the cumulative distribution function when both h and k are non-zero is: F(x) = { 1 - h [ 1 - k ( x - ξ ) / α ]1/k }1/h. The parameters h and k work together to define the function's shape, ξ affects location, and α is the scale parameter. A method of selecting parameters to minimize the Kolmogorov-Smirnov test statistic, D, was developed. The technique was first described for the …
Thermodynamic Characterization Of Dna Binding By Type I Dna Polymerases From Thermus Aquaticus And Escherichia Coli, Kausiki Datta
Thermodynamic Characterization Of Dna Binding By Type I Dna Polymerases From Thermus Aquaticus And Escherichia Coli, Kausiki Datta
LSU Doctoral Dissertations
DNA binding of the DNA polymerase I from Thermus aquaticus (Taq and Klentaq fragment) and E. coli (Klenow fragment) have been studied as a function of [salt] and temperature in order to understand their DNA binding thermodynamics. Binding of the two different species of polymerases occurs with sub-micromolar affinities in very different salt concentration ranges. Thus, at similar [KCl] the binding of Klenow is ~ 3kcal/mol (150X) tighter than the binding of Taq/Klentaq. Linkage analysis of the [KCl] dependence of DNA binding at 25°C reveals a net release of 2-3 ions for Taq/Klentaq and 4-5 ions for Klenow. DNA binding …
The Individual, The Source, And The Context: An Investigation Of Antecedents And Consequences Of Feedback Seeking Behavior, Robin Anne Cheramie
The Individual, The Source, And The Context: An Investigation Of Antecedents And Consequences Of Feedback Seeking Behavior, Robin Anne Cheramie
LSU Doctoral Dissertations
In the last twenty years, researchers have examined why individuals may proactively seek performance feedback in the workplace. Since Ashford and Cummings' (1983) seminal article, situational and individual difference variables have predominantly been examined to predict how often employees will seek feedback. One situational variable that has been researched but not sufficiently examined is the feedback context. A public or a private feedback context considers whether the presence of an audience inhibits or facilitates feedback seeking behaviors. This dissertation explores the role of the feedback context by developing a conceptual model to determine how frequently employees may seek feedback in …
Mothering Modes: Analyzing Mother Roles In Novels By Twentieth-Century United States Women Writers, Preselfannie Whitfield Mcdaniels
Mothering Modes: Analyzing Mother Roles In Novels By Twentieth-Century United States Women Writers, Preselfannie Whitfield Mcdaniels
LSU Doctoral Dissertations
For this dissertation, the following novels have been chosen as examples of the many issues that are involved in mothering in United States society: Chapter 1: Dorothy Allison’s Bastard Out of Carolina and Toni Morrison’s Beloved, Chapter 2: Toni Morrison’s Song of Solomon and Dorothy West’s The Wedding, Chapter 3: Amy Tan’s The Kitchen God’s Wife and Christina García’s Dreaming in Cuban, and Chapter 4: Betty Smith’s A Tree Grows in Brooklyn and Paule Marshall’s Brown Girl, Brownstones. For this study, the term “mothering” is specifically related to the rearing of children by the female parent. Rearing is defined as …
Tuning Polymeric Chiral Surfactants For Enhanced Enantiomeric Recognition In Micellar Electrokinetic Chromatography, Jepkoech Tarus
Tuning Polymeric Chiral Surfactants For Enhanced Enantiomeric Recognition In Micellar Electrokinetic Chromatography, Jepkoech Tarus
LSU Doctoral Dissertations
The research presented in this dissertation involves the synthesis, modification, characterization, and the application of polymeric surfactants in micellar electrokinetic chromatography (MEKC). Sodium undecenoyl-L-Leucinate (L-SUL) was synthesized and modified by use of alkali metal counterions, alcohols, and Triton X-102. Characterization of the modified poly-L-SUL was performed in order to elucidate the structural changes on the surfactants by use of four techniques. While surface tensiometry was used for the determination of the critical micelle concentration (cmc), fluorescence measurements were used for the determination of the polarity of the modified polymeric surfactants. The information about the size of the polymeric surfactants was …
Numerical Methods For The Unsteady Incompressible Navier-Stokes Equations And Their Application To The Direct Numerical Simulation Of Turbulent Flows, Frank Herbert Muldoon
Numerical Methods For The Unsteady Incompressible Navier-Stokes Equations And Their Application To The Direct Numerical Simulation Of Turbulent Flows, Frank Herbert Muldoon
LSU Doctoral Dissertations
Two new methods for the efficient parallel computation of the unsteady incompressible Navier-Stokes equations are presented. Such efficient methods are desired for large scale parallel computations of unsteady turbulent flows such as Direct Numerical Simulations (DNS). The performance of the new methods has a distinct advantage over the artificial compressibility method, in that the methods exhibit robust convergence for a variety of flow problems without extensive need for tuning computational parameters. These methods and others have been implemented in a computer program designed for massively parallel computer architectures, written by the author and used to obtain all results in this …
Investigation Of Structure-Property Relationships Of Heavy-Fermion Materials, Robin Macaluso
Investigation Of Structure-Property Relationships Of Heavy-Fermion Materials, Robin Macaluso
LSU Doctoral Dissertations
This work focuses on how local structural features influence large effective masses, magnetism, and superconductivity that are yet to be understood in heavy-fermion materials. Three sets of structurally-related materials are discussed in light of dimensionality, layering effects, choice of transition metal, coordination, and structural distortions: LnnMIn3n+2 (Ln = La, Ce; n = 1, 2, ‡; M = Co, Rh, Ir), CePdGa6, and Ce2PdGa12, and CeNiSb3. The LnnMIn3n+2 (n = 1, 2, ‡; Ln = La, Ce; M = Rh, Ir) intergrowth homologous series presents a unique opportunity to study structure-property relationships. LnnMIn3n+2 (Ln = La, Ce; n = 1, 2; …
Hemodynamic Responses Following Dynamic Resistance Exercise In Young And Older Adult Women, Rafael Antonio Reyes
Hemodynamic Responses Following Dynamic Resistance Exercise In Young And Older Adult Women, Rafael Antonio Reyes
LSU Doctoral Dissertations
This investigation examined the effects of age, exercise and test condition on hemodynamic variables, autonomic and vascular function in relation to resistance exercise (RE). The associations among these variables were also examined. METHODS: Sixteen young (21.4+1.4 yrs) and 16 older (69.7+3.9 yrs) women performed 5- and 15- repetition maximal (RM) of knee extension RE. Continuous blood pressure (BP) and electrocardiography (ECG) data were recorded. The dependent variables are reported at pre-exercise, peak exercise and recovery period. Heart rate variability data were derived from 5- and 10-min segments before and after exercise. Resting and after arterial occlusion forearm vascular function indices …
Protein Aggregation Studies: Inhibiting And Encouraging Β-Amyloid Aggregation, Jed Paul Aucoin
Protein Aggregation Studies: Inhibiting And Encouraging Β-Amyloid Aggregation, Jed Paul Aucoin
LSU Doctoral Dissertations
This work demonstrates peptide-based aggregation mediation of fibril forming peptides, notably β-amyloid (1-40), Aβ1-40. To achieve the goals of this work, Aβ1-40 aggregation was governed by ionic strength, temperature, and pH. After controlling and reproducing Aβ1-40 aggregate formation (fibrils), each peptide-based aggregation mediator was evaluated for its ability to self-aggregate and to possess surface-active properties. The incorporation of these mediators in Aβ1-40 solutions changed the surface tension and produced aggregate complexes of mediator and Aβ1-40. Evidence that Aβ1-40 fibril formation may be mediated by disorder-to-order transitions has been observed by layer formation …
Integration Of Management Tactics For The Rice Water Weevil Lissorhoptrus Oryzophilus Kuschel With Particular Emphasis On Use Of Plant Resistance (Tolerance), Li Zou
LSU Doctoral Dissertations
Studies were conducted to test the hypothesis, significant benefits can be achieved for the management of rice water weevil, Lissorhoptrus oryzophilus Kuschel, by the use of rice varieties with low levels of host plant resistance coupled with the judicious use of cultural practices and insecticides. Tolerant traits of a current commercial variety of rice, "Bengal", was manifested consistently over multiple years. Study on rice growth as effected by weevil injury showed that pruning of root systems by larvae of weevil resulted in a decrease in tiller number and shoot biomass of rice plants in the vegetative stage of growth. Yield …
Effective Literacy Instruction In The Elementary Grades, Marie Laurent Bergeron
Effective Literacy Instruction In The Elementary Grades, Marie Laurent Bergeron
LSU Doctoral Dissertations
The purpose of this study was to identify elements present in effective literacy instruction, i.e., those elements that fostered reading, speaking, listening, thinking, writing, and metacognitive skills. By examining variables that promoted literacy acquisition and achievement, a detailed account resulted which described classroom practice as related to teacher beliefs, strategies, materials, and classroom climate. The primary method of qualitative analysis used for this study was the Developmental Research Sequence (DRS) Method (Spradley, 1980). Two classrooms with exemplary teachers were studied extensively. Data collection involved the use of primary sources (interviews, observations, and student and teacher work) and secondary sources (records, …
An Integrative Model Of Clients' Decision To Adopt An Application Service Provider, Yurong Yao
An Integrative Model Of Clients' Decision To Adopt An Application Service Provider, Yurong Yao
LSU Doctoral Dissertations
Application Services Providers (ASPs) exploit the economics of delivering commercial off-the-shelf software over the Internet to many dispersed users, but the decision-making process to adopt the ASP business model can be complex requiring a comprehensive consideration of various factors. As a new form of outsourcing, the ASP business model differs from traditional outsourcing models with respect to the attributes associated with vendors, clients, and applications. These differences are expected to demand decision models that are distinct from those in the traditional IS outsourcing. In this study, an integrative model for ASP adoption that incorporates economic determinants, strategic determinants, and social …
Dna Binding Properties Of Histone-Like Protein Hu From Deinoccus Radiodurans Suggest Involvement In Dna Recombination, Sharmistha Ghosh
Dna Binding Properties Of Histone-Like Protein Hu From Deinoccus Radiodurans Suggest Involvement In Dna Recombination, Sharmistha Ghosh
LSU Doctoral Dissertations
The Histone-like protein HU is ubiquitous in eubacteria. Usually with a length of ~90 amino acids, they are predominantly homodimeric, with sequence and structural homology. Escherichia coli HU is involved in DNA repair and recombination. The crystal structure of Anabaena HU shows that it binds DNA with prolines intercalating into the DNA backbone, introducing two kinks at a spacing of 9 bp and bending the DNA through a variable angle of 105-140°. Deinococcus radiodurans is a gram positive mesophile, capable of reconstituting its genome from 1000-2000 double strand breaks incurred due to exposure to environmental extremes. In the first study, …
Non-Linear Development Of The Secular Bar-Mode Instability In Rapidly Rotating Neutron Stars, Shangli Ou
Non-Linear Development Of The Secular Bar-Mode Instability In Rapidly Rotating Neutron Stars, Shangli Ou
LSU Doctoral Dissertations
We present results from investigations of the nonlinear development of the secular bar-mode instability that is driven by gravitational radiation-reaction (GRR) forces in rotating neutron stars. Our fully three-dimensional hydrodynamical simulations have shown that, in the absence of any competing viscous effects, initially uniformly rotating axisymmetric n=1/2 polytropic stars with a ratio of rotational to gravitational potential energy greater than the critical limit are driven by GRR forces to a bar-like structure, as predicted by linear theory. The pattern frequency of the bar slows to nearly zero, that is, the bar becomes almost stationary as viewed from an inertial frame …
Foreland Basins: Lithospheric Flexure, Plate Strength And Regional Stratigraphy, John Londono
Foreland Basins: Lithospheric Flexure, Plate Strength And Regional Stratigraphy, John Londono
LSU Doctoral Dissertations
Foreland basin subsidence through time is reproduced in this study, as the flexure of an elastic beam in an inviscid fluid under the vertical stress, caused by discrete-distributed loads. Thus, seismostratigraphic data from the Timor Sea peripheral foreland basin, in northwestern Australia, and the Putumayo retroarc foreland basin in the Colombian Andes, are forward modeled, at chronostratigraphic intervals, to assess the evolving geodynamic conditions of the basins. Results show that the accommodation in foreland basins varies as the depositional basement is vertically adjusted according to the regionally isostatic compensation of the lithosphere. Distributed tectonic (thrust belts) and sedimentary loads that …
Haunted By The Uncanny - Development Of A Genre From The Late Eighteenth To The Late Nineteenth Century, Alexandra Maria Reuber
Haunted By The Uncanny - Development Of A Genre From The Late Eighteenth To The Late Nineteenth Century, Alexandra Maria Reuber
LSU Doctoral Dissertations
This dissertation traces the development of the supernatural from the late eighteenth to the late nineteenth-century. Since supernatural elements are unknown and unfamiliar, they easily arouse anxiety, fear, and even result in terror. As such they produce the effect of the uncanny and introduce the psychological component into the selected literary corpus taken from the English Gothic novel, the German Schauerroman, and the French littérature fantastique. The analysis of the selected material is based on a psychoanalytical approach using Sigmund Freud’s understanding of the uncanny, his dream analysis, and his view of the conscious and unconscious, but also considers Carl …
Applications Of The Titanium Catalyzed Cyclocarbonylation Towards Natural Product Syntheses, Jongtae Yang
Applications Of The Titanium Catalyzed Cyclocarbonylation Towards Natural Product Syntheses, Jongtae Yang
LSU Doctoral Dissertations
Recently an efficient methodology, a hetero Pauson-Khand reaction, based on titanium-catalyzed cyclocarbonylation of tethered enals for the general preparation of ¥ã-butyrolactone rings, which are typically embedded in polycyclic systems of many natural products was reported. To demonstrate this new strategy, the total syntheses of the natural products asteriscanolide and ginkgolide were investigated. The first part of this work is dedicated to synthetic efforts toward the total synthesis of asteriscanolide. Approaches highlighted by the [2,3]-Wittig rearrangement, the thermal silyloxy-Cope rearrangement, and a titanium-catalyzed cyclocarbonylation, which is the pivotal step to afford the ¥ã-butyrolactone ring. This study firmly established the utility of …