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Milling Of Inconel 718: An Experimental And Integrated Modeling Approach For Surface Roughness, Sadaf Zahoor, Adeel Shehzad, Muhammad Salman Habib Dec 2021

Milling Of Inconel 718: An Experimental And Integrated Modeling Approach For Surface Roughness, Sadaf Zahoor, Adeel Shehzad, Muhammad Salman Habib

Mechanical, Automotive & Materials Engineering Publications

Inconel 718, a hard-to-cut superalloy is reputed for having poor machining performance due to its low thermal conductivity. Consequently, the surface quality of the machined parts suffers. The surface roughness value must fall within the stringent limits to ensure the functional performance of the components used in aerospace and bioimplant applications. One doable way to enhance its machinability is the adequate dissipation of heat from the machining zone through efficient and ecofriendly cooling environment. With this perspective, an experimental and integrated green-response surface machiningbased- evolutionary optimization (G-RSM-EO) approach is presented during this investigation. The results are compared with two base-line …


Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport And Dna Damage Phenotypes In C9orf72 Als/Ftd, Melina Ramic, Nadja S. Andrade, Matthew J. Rybin, Rustam Esanov, Claes Wahlestedt, Michael Benatar, Zane Zeier Nov 2021

Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport And Dna Damage Phenotypes In C9orf72 Als/Ftd, Melina Ramic, Nadja S. Andrade, Matthew J. Rybin, Rustam Esanov, Claes Wahlestedt, Michael Benatar, Zane Zeier

All Faculty

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease with available treatments only marginally slowing progression or improving survival. A hexanu-cleotide repeat expansion mutation in the C9ORF72 gene is the most commonly known genetic cause of both sporadic and familial cases of ALS and frontotemporal dementia (FTD). The C9ORF72 expansion mutation produces five dipeptide repeat proteins (DPRs), and while the mechanistic determinants of DPR-mediated neurotoxicity remain incompletely understood, evidence suggests that disruption of nucleocytoplasmic transport and increased DNA damage contributes to pathology. Therefore, characterizing these disturbances and determining the relative contribution of different DPRs is needed to facilitate …


The George-Anne Inkwell Edition, Georgia Southern University Feb 2021

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Feb 2021

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Jan 2021

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Dec 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Nov 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Nov 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Nov 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Oct 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Oct 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Oct 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Oct 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Oct 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Sep 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Sep 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Sep 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Sep 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Aug 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Mar 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition (Spring 2020), Georgia Southern University Mar 2020

The George-Anne Inkwell Edition (Spring 2020), Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition (Spring 2020), Georgia Southern University Feb 2020

The George-Anne Inkwell Edition (Spring 2020), Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Feb 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Feb 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Feb 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George Anne Inkwell Edition, Georgia Southern University Jan 2020

The George Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Jan 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The George-Anne Inkwell Edition, Georgia Southern University Jan 2020

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The Lateral Root Density Gene Regulates Root Growth During Water Stress In Wheat, Dante F. Placido, Jaspreet Sandhu, Shirley Sato, Natalya Nersesian, Truyen Quach, Thomas Clemente, Paul Staswick, Harkamal Walia Jan 2020

The Lateral Root Density Gene Regulates Root Growth During Water Stress In Wheat, Dante F. Placido, Jaspreet Sandhu, Shirley Sato, Natalya Nersesian, Truyen Quach, Thomas Clemente, Paul Staswick, Harkamal Walia

Department of Agronomy and Horticulture: Faculty Publications

Drought stress is the major limiting factor in agriculture. Wheat, which is the most widely grown crop in the world, is predominantly cultivated in drought-prone rainfed environments. Since roots play a critical role in water uptake, root response to water limitations is an important component for enhancing wheat adaptation. In an effort to discover novel genetic sources for improving wheat adaptation, we characterized a wheat translocation line with a chromosomal segment from Agropyron elongatum, a wild relative of wheat, which unlike common wheat maintains root growth under limited-water conditions. By exploring the root transcriptome data, we found that reduced …


The Lateral Root Density Gene Regulates Root Growth During Water Stress In Wheat, Dante F. Placido, Jaspreet Sandhu, Shirley Sato, Natalya Nersesian, Truyen Quach, Thomas E. Clemente, Paul E. Staswick, Harkamal Walia Jan 2020

The Lateral Root Density Gene Regulates Root Growth During Water Stress In Wheat, Dante F. Placido, Jaspreet Sandhu, Shirley Sato, Natalya Nersesian, Truyen Quach, Thomas E. Clemente, Paul E. Staswick, Harkamal Walia

Department of Agronomy and Horticulture: Faculty Publications

Drought stress is the major limiting factor in agriculture. Wheat, which is the most widely grown crop in the world, is predominantly cultivated in drought-prone rainfed environments. Since roots play a critical role in water uptake, root response to water limitations is an important component for enhancing wheat adaptation. In an effort to discover novel genetic sources for improving wheat adaptation, we characterized a wheat translocation line with a chromosomal segment from Agropyron elongatum, a wild relative of wheat, which unlike common wheat maintains root growth under limited-water conditions. By exploring the root transcriptome data, we found that reduced …