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A Mixed-Methods Examination Among Young Adult Racially/Ethnically Diverse Bariatric Surgery Patients, Christine E. Spadola

FIU Electronic Theses and Dissertations

Bariatric, or weight loss, surgery (WLS) is known as the most effective treatment for severe obesity, and the number of bariatric surgeries performed in the United States has more than tripled over the past two decades. Despite the potential health benefits of WLS (i.e., reversal of type 2 diabetes), research has revealed problematic alcohol use among WLS patients, in part associated with the following risk factors: the prevalence of a lifetime alcohol use disorder (AUD), the Roux-en-Y gastric bypass (RYGB) procedure, younger age, and an increased post-surgical sensitivity to alcohol. There is reason to believe both (a) young adult and …

The Relationship Between Gaming Addictive Behavior, Satisfaction, And Success In Computer-Based Learning, Marlene Carrilho

Doctoral Dissertations and Projects

The purpose of this quantitative, correlational study was to examine the association between college students’ levels of gaming addictive behavior and their levels of student satisfaction and student success in a computer-based learning environment. Additionally, gender was investigated as a moderator of the association between gaming addictive behavior and student success and between gaming addictive behavior and student satisfaction. Data was collected through online surveys from a convenience sample of undergraduate students enrolled at a large, Southern Association of Colleges and Schools (SACS)-accredited, evangelical Christian university located in Virginia. The statistical program SPSS 22.0 was used for the analyses. Hierarchical …

Social Media Network Participation And Academic Performance In Senior High Schools In Ghana, Jeffrey Mingle, Musah Adams

Library Philosophy and Practice (e-journal)

This study looks at social media network participation and academic performance in senior high schools. The study was aimed at identifying social media network sites and their usage among students, how students networked and participated on social media networks, time invested by students on social networks, the effects of social media on students’ grammar and spelling as well as the effects of social network participation on the student’s academic performance within the context of the social learning and the use and gratification theories.

To achieve the objectives of the research, the study used a mixed method approach which involved the …

Avoidance As An Explanatory Mechanism For Poor Outcomes In Treatment For Substance Use Disorders, Andrew Oakland

Department of Psychology: Dissertations, Theses, and Student Research

Substance use disorders (SUDs) are prevalent and lead to significant impairments in people's lives in a variety of ways. One area which has gained attention is that of SUDs and their high comorbidity with mood and anxiety disorders. Many theories exist as to why these conditions often occur together, and the self-medication hypothesis is one that has perhaps the most research and general support behind it. The self-medication hypothesis states that individuals use substances to reduce negative affect which creates a feedback loop of negative reinforcement. Individuals then develop problematic substance use in addition to emotional dysregulation. One recent theory …

Aversive Stimuli Drive Drug Seeking In A State Of Low Dopamine Tone, Robert C. Twining, Daniel S. Wheeler, Amanda L. Ebben, Andre J. Jacobsen, Mykel A. Robble, John R. Mantsch, Robert A. Wheeler

Biological Sciences Faculty Research and Publications

Background

Stressors negatively impact emotional state and drive drug seeking, in part, by modulating the activity of the mesolimbic dopamine system. Unfortunately, the rapid regulation of dopamine signaling by the aversive stimuli that cause drug seeking is not well characterized. In a series of experiments, we scrutinized the subsecond regulation of dopamine signaling by the aversive stimulus, quinine, and tested its ability to cause cocaine seeking. Additionally, we examined the midbrain regulation of both dopamine signaling and cocaine seeking by the stress-sensitive peptide, corticotropin releasing factor (CRF).

Methods

Combining fast-scan cyclic voltammetry with behavioral pharmacology, we examined the effect of …

Drug Predictive Cues Activate Aversion-Sensitive Striatal Neurons That Encode Drug Seeking, Daniel S. Wheeler, Mykel A. Robble, Emily M. Hebron, Matthew J. Dupont, Amanda L. Ebben, Robert A. Wheeler

Biomedical Sciences Faculty Research and Publications

Drug-associated cues have profound effects on an addict’s emotional state and drug-seeking behavior. Although this influence must involve the motivational neural system that initiates and encodes the drug-seeking act, surprisingly little is known about the nature of such physiological events and their motivational consequences. Three experiments investigated the effect of a cocaine-predictive stimulus on dopamine signaling, neuronal activity, and reinstatement of cocaine seeking. In all experiments, rats were divided into two groups (paired and unpaired), and trained to self-administer cocaine in the presence of a tone that signaled the immediate availability of the drug. For rats in the paired group, …

Exposure To Kynurenic Acid During Adolescence Increases Sign-Tracking And Impairs Long-Term Potentiation In Adulthood, Nicole E. Deangeli, Travis P. Todd, Stephen E. Chang, Hermes H. Yeh, Pamela W. Yeh, David J. Bucci

Dartmouth Scholarship

Changes in brain reward systems are thought to contribute significantly to the cognitive and behavioral impairments of schizophrenia, as well as the propensity to develop co-occurring substance abuse disorders. Presently, there are few treatments for persons with a dual diagnosis and little is known about the neural substrates that underlie co-occurring schizophrenia and substance abuse. One goal of the present study was to determine if a change in the concentration of kynurenic acid (KYNA), a tryptophan metabolite that is increased in the brains of people with schizophrenia, affects reward-related behavior. KYNA is an endogenous antagonist of NMDA glutamate receptors and …