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Shiga Toxin Of Enterohemorrhagic Escherichia Coli Type O157:H7 Promotes Intestinal Colonization, Cory M. Robinson, James F. Sinclair, Michael J. Smith, Alison D. O'Brien
Shiga Toxin Of Enterohemorrhagic Escherichia Coli Type O157:H7 Promotes Intestinal Colonization, Cory M. Robinson, James F. Sinclair, Michael J. Smith, Alison D. O'Brien
Uniformed Services University of the Health Sciences
Enterohemorrhagic Escherichia coli (EHEC) 0157:H7 is a food-borne pathogen that can cause bloody diarrhea and, occasionally, acute renal failure as a consequence of Shiga toxin (Stx) production by the organism. Stxs are potent cytotoxins that are lethal to animals at low doses. Thus, Stxs not only harm the host but, as reported here, also significantly enhance the capacity of EHEC O157:H7 to adhere to epithelial cells and to colonize the intestines of mice. Tissue culture experiments showed that this toxin-mediated increase in bacterial adherence correlated with an Stx-evoked increase in a eukaryotic receptor for the EHEC O157:H7 attachment factor intimin.
Motivation, Psychological Distress And Exercise Adherence Following Myocardial Infarction, Angela Ljubic, Frank P. Deane, Robert Zecchin, Richard Denniss
Motivation, Psychological Distress And Exercise Adherence Following Myocardial Infarction, Angela Ljubic, Frank P. Deane, Robert Zecchin, Richard Denniss
Faculty of Health and Behavioural Sciences - Papers (Archive)
Fifty patients with myocardial infarction were recruited from a hospital based Cardiac Education and Assessment Program (CEAP) in Sydney, Australia. The Exercise Motivation Inventory-2 (EMI-2) and the Depression, Anxiety and Stress Scale (DASS) were administered prior to commencement in the program and re-administered by telephone interview at 5-month followup. Four exercise adherence measures were completed: attendance, exercise stress test, self-report ratings and a 7-day activity recall interview. There was a 46% adherence rate for MI patients during the hospital based CEAP. Of those individuals who completed CEAP, 91% obtained functional improvement on the exercise stress test. For the 38 patients …