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Blood Volume And Hemoglobin Oxygenation Response Following Electrical Stimulation Of Human Cortex, Minah Suh, Sonya Bahar, Ashesh Mehta, Theodore Schwartz May 2006

Blood Volume And Hemoglobin Oxygenation Response Following Electrical Stimulation Of Human Cortex, Minah Suh, Sonya Bahar, Ashesh Mehta, Theodore Schwartz

Physics Faculty Works

No abstract provided.


Low Doses Of Memantine Disrupt Memory In Adult Rats, Catherine Creeley, David Wozniak, Joanne Labruyere, George Taylor, John Olney Apr 2006

Low Doses Of Memantine Disrupt Memory In Adult Rats, Catherine Creeley, David Wozniak, Joanne Labruyere, George Taylor, John Olney

Psychology Faculty Works

Memantine, a drug recently approved for treatment of Alzheimer’s disease, has been characterized as a unique NMDA antagonist that confers protection against excitotoxic neurodegeneration without the serious side effects that other NMDA antagonists are known to cause. In the present study, we determined what dose of memantine is required to protect the adult rat brain against an NMDA receptor-mediated excitotoxic process and then tested that dose and a range of lower doses to determine whether the drug in this dose range is associated with significant side effects. Consistent with previous research, we found that memantine confers a neuroprotective effect beginning …


Understanding Reported Cognitive Dysfunction In Older Adults With Cardiovascular Disease, Robert H. Paul, John Gunstad, Ronald A. Cohen, David F. Apr 2006

Understanding Reported Cognitive Dysfunction In Older Adults With Cardiovascular Disease, Robert H. Paul, John Gunstad, Ronald A. Cohen, David F.

Psychology Faculty Works

High HIV-1 DNA (HIV DNA) levels in peripheral blood mononuclear cells (PBMC) correlate with HIV-1-associated dementia (HAD) in patients on highly active antiretroviral therapy (HAART). If this relationship also exists among HAART-naïve patients, then HIV DNA may be implicated in the pathogenesis of HAD. In this study, we evaluated the relationship between HIV DNA and cognition in subjects naïve to HAART in a neuro AIDS cohort in Bangkok, Thailand. Subjects with and without HAD were recruited and matched for age, gender, education, and CD4 cell count. PBMC and cellular subsets were analyzed for HIV DNA using real-time PCR. The median …


Hiv Dna And Dementia In Treatment-Naive Hiv-1-Infected Individuals In Bangkok, Thailand, Robert H. Paul, Bruce Shiramizu, Silvia Ratto-Kim, Pasiri Sithinamsuwan Jan 2006

Hiv Dna And Dementia In Treatment-Naive Hiv-1-Infected Individuals In Bangkok, Thailand, Robert H. Paul, Bruce Shiramizu, Silvia Ratto-Kim, Pasiri Sithinamsuwan

Psychology Faculty Works

High HIV-1 DNA (HIV DNA) levels in peripheral blood mononuclear cells (PBMC) correlate with HIV-1-associated dementia (HAD) in patients on highly active antiretroviral therapy (HAART). If this relationship also exists among HAART-naïve patients, then HIV DNA may be implicated in the pathogenesis of HAD. In this study, we evaluated the relationship between HIV DNA and cognition in subjects naïve to HAART in a neuro AIDS cohort in Bangkok, Thailand. Subjects with and without HAD were recruited and matched for age, gender, education, and CD4 cell count. PBMC and cellular subsets were analyzed for HIV DNA using real-time PCR. The median …