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Medicine and Health Sciences

2001

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Changing Incidence Of Oral And Maxillofacial Tumours In East Java, Indonesia, 1987-1992. Part 2: Malignant Tumours, T. I. Budhy, S. D. Soenarto, H. B. Yaacob, W.C. Ngeow Dec 2001

Changing Incidence Of Oral And Maxillofacial Tumours In East Java, Indonesia, 1987-1992. Part 2: Malignant Tumours, T. I. Budhy, S. D. Soenarto, H. B. Yaacob, W.C. Ngeow

Wei Cheong Ngeow

A total of 2193 tumours of the mouth and jaw diagnosed at the Laboratorium Patologi Anatomi Fakultas Kedokteran Universitas Airlangga, Indonesia from 1987 to 1992, inclusive, was studied. Malignant tumours constituted 45.3% of the lesions. Almost 71% of the malignant tumours were squamous cell carcinomas. The remainder were salivary gland tumours (21.5%) and sarcomas (4.5%). The male to female ratio for malignant tumours was 5.1:4.7. The incidence of malignant tumours per 100,000 population over the 6-year study period was 2.64. The yearly incidence seemed to increase except in 1990, when it dropped. The incidence of squamous cell carcinoma over the …


Computed Tomography To Assess Pulmonary Injury Associated With Concurrent Chemo-Radiotherapy For Inoperable Non-Small Cell Lung Cancer, Galit Aviram, Edward Yu, Patricia Tai, Michael Lefcoe Nov 2001

Computed Tomography To Assess Pulmonary Injury Associated With Concurrent Chemo-Radiotherapy For Inoperable Non-Small Cell Lung Cancer, Galit Aviram, Edward Yu, Patricia Tai, Michael Lefcoe

Edward Yu

OBJECTIVE: To characterize serial computed tomography (CT) findings of pulmonary injury after a uniform regimen of concurrent chemo-radiotherapy in inoperable non-small cell lung cancer, and to compare the radiation-induced lung toxicity with other concurrent chemo-radiation regimens. METHODS: Twenty-four patients with advanced non-small cell lung cancer received 2 induction cycles of cisplatin and vinblastine, followed by 2 further cycles of cisplatin and vinblastine, concurrent with 60 Gy radiation at 2 Gy per fraction. Radiation-induced lung injury in the acute and chronic phases was assessed by serial CT scans and compared with preradiation baseline scans. Acute radiation pneumonitis was evaluated using the …


Aging And The Public Health Impact Of Dementia, Ron Brookmeyer, Claudia Kawas Nov 2001

Aging And The Public Health Impact Of Dementia, Ron Brookmeyer, Claudia Kawas

Ron Brookmeyer

No abstract provided.


Effect Of Combination Therapy Including Protease Inhibitors On Mortality Among Children And Adolescents With Hiv-1 Nov 2001

Effect Of Combination Therapy Including Protease Inhibitors On Mortality Among Children And Adolescents With Hiv-1

Joseph Cervia

No abstract provided.


Who Should Foot The Bill For Continuing Review Of Research?, Charles Weijer Oct 2001

Who Should Foot The Bill For Continuing Review Of Research?, Charles Weijer

Charles Weijer

No abstract provided.


Agen Resmi Titan Gel Di Cirebon Wa : 082134326660, Nana Putri Oct 2001

Agen Resmi Titan Gel Di Cirebon Wa : 082134326660, Nana Putri

Nana OlShop

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Quarrington’S Hockey Schtick: A Literary Analysis, Don Morrow Sep 2001

Quarrington’S Hockey Schtick: A Literary Analysis, Don Morrow

Donald Morrow

No abstract provided.


Concentric Retinitis Pigmentosa: Clinicopathologic Correlations, Ann Milam, Elaine De Castro, Julie Smith, Wai-Xing Tang, Sinoj John, Michael Gorin, Edwin Stone, Gustavo Aguirre, Samuel Jacobson Sep 2001

Concentric Retinitis Pigmentosa: Clinicopathologic Correlations, Ann Milam, Elaine De Castro, Julie Smith, Wai-Xing Tang, Sinoj John, Michael Gorin, Edwin Stone, Gustavo Aguirre, Samuel Jacobson

Gustavo D. Aguirre, VMD, PhD


Progressive concentric (centripetal) loss of vision is one pattern of visual field loss in retinitis pigmentosa. This study provides the first clinicopathologic correlations for this form of retinitis pigmentosa. A family with autosomal dominant concentric retinitis pigmentosa was examined clinically and with visual function tests. A post-mortem eye of an affected 94 year old family member was processed for histopathology and immunocytochemistry with retinal cell specific antibodies. Unrelated simplex/multiplex patients with concentric retinitis pigmentosa were also examined. Affected family members of the eye donor and patients from the other families had prominent peripheral pigmentary retinopathy with more normal appearing central …


Fine Mapping Of Canine Xlpra Establishes Homology Of The Human And Canine Rp3 Intervals, Qi Zhang, Gregory M. Acland, Barbara Zangerl, J. L. Johnson, Zuohua Mao, Caroline Zeiss, Elaine A. Ostrander, Gustavo D. Aguirre Sep 2001

Fine Mapping Of Canine Xlpra Establishes Homology Of The Human And Canine Rp3 Intervals, Qi Zhang, Gregory M. Acland, Barbara Zangerl, J. L. Johnson, Zuohua Mao, Caroline Zeiss, Elaine A. Ostrander, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

Purpose: Canine X-linked progressive retinal atrophy (XLPRA) is a hereditary, progressive retinal degeneration that has been mapped previously to the canine X chromosome in a region flanked by the dystrophin (DMD) and tissue inhibitor of metalloproteinase 1 (TIMP1) genes, and is tightly linked to the gene RPGR. The comparable region of the human X chromosome includes the disease locus for RP3, an X-linked form of retinitis pigmentosa, although the current canine disease interval is much larger.
Methods: To refine the map of the canine XLPRA disease interval, 11 X-linked markers were mapped, both meiotically, in two extensive …


Cloning Of Canine Γ-Tubulin (Tubg1) Cdna And Mapping To Cfa9, Duska J. Sidjanin, F Xue, J Mcelwee, Jennifer L. Johnson, C Holmgren, Cathryn S. Mellersh, Elaine A. Ostrander, Gregory M. Acland, Gustavo D. Aguirre Sep 2001

Cloning Of Canine Γ-Tubulin (Tubg1) Cdna And Mapping To Cfa9, Duska J. Sidjanin, F Xue, J Mcelwee, Jennifer L. Johnson, C Holmgren, Cathryn S. Mellersh, Elaine A. Ostrander, Gregory M. Acland, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

No abstract provided.


Internal Consistency And Intercriterion Overlap Within And Between Dsm-Iv Axis Ii Personality Disorders: Findings From The Collaborative Longitudinal Study Of Personality Disorders, Carlos M. Grilo, Thomas H. Mcglashan, Leslie C. Morey, John G. Gunderson, Andrew E. Skodol, M. Tracie Shea, Charles A. Sanislow, Mary C. Zanarini, Donna S. Bender, John M. Oldham, Ingrid Dyck, Robert L. Stout Sep 2001

Internal Consistency And Intercriterion Overlap Within And Between Dsm-Iv Axis Ii Personality Disorders: Findings From The Collaborative Longitudinal Study Of Personality Disorders, Carlos M. Grilo, Thomas H. Mcglashan, Leslie C. Morey, John G. Gunderson, Andrew E. Skodol, M. Tracie Shea, Charles A. Sanislow, Mary C. Zanarini, Donna S. Bender, John M. Oldham, Ingrid Dyck, Robert L. Stout

Charles A. Sanislow, Ph.D.

Objective: To evaluate performance characteristics of DSM-IV Personality Disorders (PDs) criteria.

Method: Six hundred and sixty-eight adults recruited for the Collaborative Longitudinal Personality Disorders Study (CLPS) were assessed with diagnostic interviews.

Results: Within-category inter-relatedness was evaluated by Cronbach’s alpha and median intercriterion correlations (MIC). Cronbach’s alpha ranged from 0.47 to 0.87 (median=0.71); seven of the 10 PDs had alphas greater than 0.70. Between-category criterion overlap was evaluated by ‘inter-category’ intercriterion correlations between all PD pairs (ICMIC). ICMIC values (median=0.08) were lower than MIC values (median=0.23). Diagnostic efficiency statistics (sensitivity, specificity, positive predictive power and negative predictive power were calculated for …


Preconferance Aacc 2011//Behind The Eyes: The Neurobiology Of Relationships And Spirituality, Gary A. Sibcy Phd Sep 2001

Preconferance Aacc 2011//Behind The Eyes: The Neurobiology Of Relationships And Spirituality, Gary A. Sibcy Phd

Gary Sibcy

No abstract provided.


Parametric And Nonparametric Methods For Understanding The Relationship Between Carcinogen-Induced Dna Adduct Levels In Distal And Proximal Regions Of The Colon., Jeffrey S. Morris, Naisyin Wang, Joanne R. Lupton, Robert S. Chapkin, Nancy D. Turner, Mee-Young Hong, Raymond J. Carroll Sep 2001

Parametric And Nonparametric Methods For Understanding The Relationship Between Carcinogen-Induced Dna Adduct Levels In Distal And Proximal Regions Of The Colon., Jeffrey S. Morris, Naisyin Wang, Joanne R. Lupton, Robert S. Chapkin, Nancy D. Turner, Mee-Young Hong, Raymond J. Carroll

Jeffrey S. Morris

An important problem in studying the etiology of colon cancer is understanding the relationship between DNA adduct levels (broadly, DNA damage) in cells within colonic crypts in distal and proximal parts of the colon, following treatment with a carcinogen and different types of diet. In particular, it is important to understand whether rats who have elevated adduct levels in particular positions in distal region crypts also have elevated levels in the same positions of the crypts in proximal regions, and whether this relationship depends on diet. We cast this problem as estimating the correlation function of two responses as a …


Monte Carlo Simulations And Measurement Of Dna Damage From X-Ray-Triggered Auger Cascades In Iododeoxyuridine (Iudr), S. Karnas, V. Moiseenko, E. Yu, P. Truong, J. Battista Aug 2001

Monte Carlo Simulations And Measurement Of Dna Damage From X-Ray-Triggered Auger Cascades In Iododeoxyuridine (Iudr), S. Karnas, V. Moiseenko, E. Yu, P. Truong, J. Battista

Edward Yu

We investigated the DNA damage from Auger electrons emitted from incorporated stable iodine (127I), following photoelectric absorption of external x-rays. The effectiveness of the Auger electrons in producing DNA double-strand breaks (DSB) was determined theoretically, using Monte Carlo simulations of the radiation physics and chemistry, and was shown to be in reasonable agreement with DNA damage measured using the comet assay. The DSB yields were measured in CHO cells for 60Co (as a non-Auger-promoting radiation) and for tungsten-filtered 100 kVp x-rays capable of producing Auger electron emission. The theoretical study showed that on average, 2.5 Auger electrons were emitted for …


Minimal Risk And Its Implications, Charles Weijer Aug 2001

Minimal Risk And Its Implications, Charles Weijer

Charles Weijer

No abstract provided.


Role Of Wireless Technology In Meeting Global Health Care Needs., Nat Quansah Aug 2001

Role Of Wireless Technology In Meeting Global Health Care Needs., Nat Quansah

Nat Quansah

No abstract provided.


Using Treatment Interruptions To Palliate The Toxicity From Concurrent Chemoradiation For Limited Small Cell Lung Cancer Decreases Survival And Disease Control, Gregory Videtic, Karen Fung, Anna Tomiak, Larry Stitt, A. Dar, Pauline Truong, Edward Yu, Mark Vincent, Walter Kocha Jul 2001

Using Treatment Interruptions To Palliate The Toxicity From Concurrent Chemoradiation For Limited Small Cell Lung Cancer Decreases Survival And Disease Control, Gregory Videtic, Karen Fung, Anna Tomiak, Larry Stitt, A. Dar, Pauline Truong, Edward Yu, Mark Vincent, Walter Kocha

Edward Yu

BACKGROUND AND PURPOSE: We analyzed the impact on survival outcomes of treatment interruptions due to toxicity arising during the concurrent phase of chemotherapy/radiotherapy (ChT/RT) for our limited-stage small-cell cancer (LSCLC) population over the past 10 years. MATERIALS AND METHODS: From 1989 to 1999, 215 patients received treatment for LSCLC, consisting of six cycles of alternating cyclophosphamide/doxorubicin or epirubicin/vincristine (CAV; CEV) and etoposide/cisplatin (EP). Thoracic RT was started with EP at either the second or third cycle (85% of patients). RT dose was either 40 Gy in 15 fractions over 3 weeks or 50 Gy in 25 fractions over 5 weeks, …


Should Physicians Accept Gifts From Their Patients? No: Gifts Debase The True Value Of Care, Charles Weijer Jul 2001

Should Physicians Accept Gifts From Their Patients? No: Gifts Debase The True Value Of Care, Charles Weijer

Charles Weijer

No abstract provided.


In Utero Aav-Mediated Gene Transfer To Rabbit Pulmonary Epithelium, M. P. Boyle, Raymond Enke, R. J. Adams, W. B. Guggino, P. L. Zeitlin Jul 2001

In Utero Aav-Mediated Gene Transfer To Rabbit Pulmonary Epithelium, M. P. Boyle, Raymond Enke, R. J. Adams, W. B. Guggino, P. L. Zeitlin

Ray Enke Ph.D.

No abstract provided.


Mental Health Parity: National And State Perspectives 2001: A Report To The Florida Legislature, Bruce Lubotsky Levin, Ardis Hanson, Richard Coe Jul 2001

Mental Health Parity: National And State Perspectives 2001: A Report To The Florida Legislature, Bruce Lubotsky Levin, Ardis Hanson, Richard Coe

Ardis Hanson

The federal Mental Health Parity Act of 1996 requires insurers to offer the same benefits for mental disorders and substance abuse as they would for physical disorders, including any annual or lifetime limitations and restrictions placed upon such coverage. This report examines actuarial studies, the current state of parity legislation across the nation, cost of treatment issues, and the impact on Florida should parity legislation be passed.


Transforming Self-Rated Health And The Sf-36 Scales To Include Death And Improve Interpretability, Paula Diehr Jul 2001

Transforming Self-Rated Health And The Sf-36 Scales To Include Death And Improve Interpretability, Paula Diehr

Paula Diehr

BACKGROUND: Most measures of health-related quality of life are undefined for people who die. Longitudinal analyses are often limited to a healthier cohort (survivors) that cannot be identified prospectively, and that may have had little change in health. OBJECTIVE: To develop and evaluate methods to transform a single self-rated health item (excellent to poor; EVGGFP) and the physical component score of the SF-36 (PCS) to new variables that include a defensible value for death. METHODS: Using longitudinal data from two large studies of older adults, health variables were transformed to the probability of being healthy in the future, conditional on …


The Corporate Practice Of Medicine: Competition And Innovation In Health Care (Book Review), Linda Treiber Jun 2001

The Corporate Practice Of Medicine: Competition And Innovation In Health Care (Book Review), Linda Treiber

Linda A. Treiber

Review of the book "The Corporate Practice of Medicine: Competition and Innovation in Health Care," by James C. Robinson


Informing Patients Of Uncertainty In Clinical Trials, S. Halpern, J. Karlawish, Charles Weijer Jun 2001

Informing Patients Of Uncertainty In Clinical Trials, S. Halpern, J. Karlawish, Charles Weijer

Charles Weijer

No abstract provided.


Targeting Youth And Concerned Smokers: Evidence From Canadian Tobacco Industry Documents, Richard W. Pollay Jun 2001

Targeting Youth And Concerned Smokers: Evidence From Canadian Tobacco Industry Documents, Richard W. Pollay

Richard W. Pollay

No abstract provided.


Home Game: Quarrington’S Eccentric Literary Foul Ball, Don Morrow May 2001

Home Game: Quarrington’S Eccentric Literary Foul Ball, Don Morrow

Donald Morrow

No abstract provided.


Practice Guideline On Prophylactic Cranial Irradiation In Small-Cell Lung Cancer, Jaro Kotalik, Edward Yu, Barbara Markman, William Evans May 2001

Practice Guideline On Prophylactic Cranial Irradiation In Small-Cell Lung Cancer, Jaro Kotalik, Edward Yu, Barbara Markman, William Evans

Edward Yu

Purpose: To develop an evidence-based clinical practice guideline that would address the following questions: (a) What is the role of prophylactic cranial irradiation (PCI) in patients with limited or extensive stage small-cell lung cancer (SCLC) who have achieved complete remission in response to induction therapy (chemotherapy or chemoradiotherapy)? (b) What dose and fractionation schedules of PCI are optimal? (c) Does the use of PCI in patients with SCLC in complete remission affect quality of life? Survival, disease-free survival, quality of life, and adverse effects were the outcomes of interest. Methods and materials: A systematic review of the published literature was …


Biomechanical Difference Between Loaded Countermovement And Static Squat Jumps, S. G. S. Coleman, C. Karatzaferi, Michael H. Stone May 2001

Biomechanical Difference Between Loaded Countermovement And Static Squat Jumps, S. G. S. Coleman, C. Karatzaferi, Michael H. Stone

Michael H. Stone

It was the aim of this study to assess differences between countermovement (CMJ) and static (SJ) unloaded and loaded squat jumps. Eight male national/international level athletes and badminton players performed a series of jumps on two Kistler force plates. Maximum vertical force (Fmax) and rate of force development (RFDmax), net impulse (Impnet) and vertical take-off velocity (VT-O) were calculated and compared using a Two-Way (Jump x Load) ANOVA with two repeated factors. Fmax increased significantly with load and displayed a significant interaction with jump type. RFDmax showed significant jump main and interaction effects. Impnet only changed significantly with load. These …


Effectiveness Of Germicidal Uv Radiation For Reducing Fungal Contamination Within Air Handling Units, E Levetin, R Shaughnessy, Christine A. Rogers, R Scheir May 2001

Effectiveness Of Germicidal Uv Radiation For Reducing Fungal Contamination Within Air Handling Units, E Levetin, R Shaughnessy, Christine A. Rogers, R Scheir

Christine A. Rogers

Levels of fungi growing on insulation within air-handling units (AHUs) in an office building and levels of airborne fungi within AHUs were measured before the use of germicidal UV light and again after 4 months of operation. The fungal levels following UV operation were significantly lower than the levels in control AHUs.


Circulating Endothelial Cells After Transplantation, A. B. Salazar, Vivian C. Mcalister, R. Gupta, A. S. Macdonald May 2001

Circulating Endothelial Cells After Transplantation, A. B. Salazar, Vivian C. Mcalister, R. Gupta, A. S. Macdonald

Vivian C. McAlister

Fate of renal allografts that survive vascular rejection To measure the outcome for grafts that survive early vascular rejection, we reassessed 411 biopsy samples taken from 260 patients in the first month after transplantation. Patients were separated into four classifications, according to Banff 1997 criteria: vascular rejection (36 patients); acute cellular rejection ([ACR] 30); no rejection (194); and 974 recipients from the same era who did not undergo biopsy. Other than graft histology, the groups did not differ for known adverse prognostic factors. The mean follow-up period was 6·03 years (SD 4·7). Graft survival is presented in the table. The …


One Hundred - Not Out: Henry Roxborough’S Shaping Of Canadian Sport History, Don Morrow Apr 2001

One Hundred - Not Out: Henry Roxborough’S Shaping Of Canadian Sport History, Don Morrow

Donald Morrow

No abstract provided.