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Study Of Ace And Rage Genes Polymorphism In Children With Type 1 Diabetes Presented By Renal Complications, Maha Atef Tawfik, Marwa Said Tawfik El-Sharawy, Naglaa Fathy Barsem

Menoufia Medical Journal

Objectives: To study the relation between angiotensin I converting enzyme (ACE) and receptor for advanced glycation end products (RAGE) genes in children with type 1 diabetes presented by renal complications. Background: In patients with type 1 diabetes, an association has been found between an insertion/deletion (I/D) polymorphism in the gene for ACE and the presence of diabetic nephropathy. Methods: A cross section study was conducted on 50 Egyptian children with type 1 diabetes presented by renal complications from our endocrinology, genetic unit and outpatient clinic in pediatric department, Menoufia University, during a period time from April 2021 to October 2022. …

Conference Proceedings: Select Abstracts Presented At 2023 Advocate Aurora Scientific Day

Journal of Patient-Centered Research and Reviews

This abstract supplement includes findings presented at the 49th annual Advocate Aurora Scientific Day on May 24, 2023. The Scientific Day symposium provides a virtual forum for the sharing of preliminary results from research and case studies conducted by faculty, fellows, residents, and other health professionals associated with Illinois-based Advocate Health Care and Wisconsin-based Aurora Health Care.

How Long Does It Take To Master Laryngeal Visualization Using Flexible Nasolaryngoscopy In Children?, Kieran Boochoon, Julina Ongkasuwan, Annie Ahn, Mary Musso, Yi-Chun Carol Liu

Graduate Medical Education Research Journal

Background: To assess when residents become proficient in performing flexible nasolaryngoscopy (FNL) in the pediatric population.

Objective: To objectively evaluate the quality of FNL by year of residency training.

Methods: Ninety-five pediatric FNL’s were performed by otolaryngology residents and pediatric otolaryngology fellows (postgraduate year [PGY] 1 – 6). Three pediatric otolaryngologists rated the FNL videos (anonymized and without sound) using the Modified Cormack-Lehane scoring system (MCLS). Data analysis was performed using two-way ANOVA and Tukey-Kramer adjustment.

Results: Overall, there was a significant difference in the quality of the FNL based on the year of training (p

Conclusion: The quality …

Pediatric Providers’ Experiences Assessing Young Children’S Emotions And Behaviors, Vaibhavi Venkataramanan, Akira Isaac B.S., Sara Bufferd Ph.D.

The Cardinal Edge

Introduction: Preschool-aged children experience anxiety and mood-related emotions (e.g., irritability, fears) and behaviors (e.g., tantrums) that are developmentally normative, but can overlap with psychopathology, making assessment challenging (Bufferd et al.,2016). Most children see pediatric medical providers annually, and providers can evaluate them. However, providers face challenges like limited training and time (Bean et al.,2000;Heneghan et al.,2008). Accurate and early identification of emotional and behavioral difficulties is critical to support young children’s mental health and prevent worsening problems.

Methods: Participants included N=22 pediatricians who see 3-5-year-old children in their practice. Pediatricians completed an online survey about their experiences assessing young …

Trends In Length Of Stay: Experience From A Tertiary Care Pediatric Rehabilitation Unit In Saudi Arabia., Sami Ullah, Ahmad Zaheer Qureshi, Waqas Sami, Amara Ilyas, Sherif Samir Abdelmaksoud Tantawy, Sarah Samir Abdulakarim Alqatari, Hasan Shacfe, Colleen Ann Wunderlich

Internet Journal of Allied Health Sciences and Practice

Background: Pediatric rehabilitation units offer unique challenges due to complex rehabilitation needs of children based on their age group and diagnosis. Length of stay (LOS) is an indirect measure of hospital cost and efficiency of a clinical service and it is important to determine the factors affecting LOS in hospitalized children undergoing inpatient rehabilitation. Methods: Record of 350 children (males: 222, female: 128) who underwent inpatient pediatric rehabilitation program at King Fahad Medical City, Riyadh Saudi Arabia during 2011 to 2018 were reviewed. Diagnoses were categorized into cerebral palsy, spinal cord injury, traumatic brain injury, non-traumatic brain injury and others. …

How Did That Get There? A Case Series Of Adolescent Foreign Bodies, Justin Ian Hanson, Paul Bomar, Sarah Kleist, Denver Rogalla, Lori Crihfield, Scott Gutovitz

HCA Healthcare Journal of Medicine

Introduction

Pediatric foreign bodies (FBs) come in many shapes and sizes, and the method by which they enter the body can greatly impact the level of acuity at presentation. Most FBs in children are found in those younger than 5 years old, but the following 3 cases were found in adolescent patients.

Case Presentation

We report on 3 adolescent patients who presented to a single community-based emergency department with the chief complaint of abdominal pain and were found to have complications of abdominal FBs. If undiagnosed, the initial indolent courses of FBs can lead to serious complications, as shown in …

Covid-19 Disease Characterization And Outcomes Comparison In Pediatrics, Rachel Rowland, Abigail Schauble, Brendon Cornett

HCA Healthcare Journal of Medicine

Background

It has been reported that children experience less severe COVID-19 symptoms than adults; however, the literature that supports this idea is evolving. The purpose of this study was to retrospectively characterize hospitalized COVID-19-positive pediatric patients with a focus on the assessment of risk factors for poorer outcomes, mortality, and evaluation of interventions utilized and associated clinical outcomes.

Methods

We conducted a multi-center retrospective chart review of patients 18 years old or younger who were COVID-19 positive and admitted to any US HCA Healthcare Pediatric service line between January 1, 2020, and November 30, 2020. We identified 6081 children across …

Phosphorus: The Forgotten Electrolyte In The Paediatric Intensive Care Unit, Fady Mohamed Elgendy, Wafaa Abdelaziz Eladrosy, Muhammad Said El-Mekkawy

Menoufia Medical Journal

Objective To evaluate prevalence of hypophosphatemia and hyperphosphatemia and their association with outcome among critically ill children. Background Phosphorus is essential element for various biological functions but data about serum phosphorus level abnormalities among critically ill children are limited. Patients and methods Prospective observational study including children admitted into Pediatric Intensive Care Unit (PICU). Serum phosphorus was measured on admission, day4, day8, and day12. Pediatric Sequential Organ Failure Assessment (pSOFA) score was calculated on admission. Hypophosphatemia and hyperphosphatemia risk factors were determined. Results Hypophosphatemia and hyperphosphatemia were generally non-severe. Hypophosphatemic patients had higher frequency of sepsis on admission compared with …

Assessment Of Serum Copeptin Levels In Pediatric Patients With Sickle Cell Anemia, Mahmoud Ahmed El-Hawy, Amira M.F. Shehata, Basem Abd El-Fattah El-Gazzar, Ahmed Mostafa Ahmed Esmaiel, Mai El-Sayad Abd El-Hamid El-Saeedy

Menoufia Medical Journal

Objectives: To assess the serum copeptin levels in children with Sickle cell anemia. Background: Sickle cell anemia (SCA) is one of the most common hereditary diseases in the world. Copeptin is the C-terminal part of the prohormone for provasopressin and seems clinically relevant in various clinical conditions. Methods: This is a case control study conducted on 62 subjects, 31 pediatric patients with Sickle cell anemia and 31 healthy children, all aged 1 year to 18 to assess the serum copeptin levels in children with Sickle cell anemia. Who attended pediatric hematology clinics of the Menoufia university hospitals, during a period …

Assessment Of Serum Asymmetric Dimethylarginine Level In Children With Beta-Thalassemia, Seham M. Ragab, Sally M. El-Hefnawy, Eman R.A. Selima, Asmaa A. Mohmoud, Sara A. Elshehaby

Menoufia Medical Journal

Objective

The aim was to evaluate serum asymmetric dimethylarginine (ADMA) level in pediatric patients who received a diagnosis of beta-thalassemia as a predictor of endothelial dysfunction.

Background

Beta-thalassemia is one of most common global autosomal recessive disorders. It causes poor growth and skeletal abnormalities along with hemolytic anemia that regularly involves long-term blood transfusions.

Methods

This cross-sectional study included 60 children divided equally in two groups. The patient group was previously diagnosed with beta-thalassemia major (β-TM), and the control group was healthy subjects who were age, sex, and socioeconomically matched with the patient group. Both groups were evaluated regarding complete …

Feasibility Of Establishing A Neonatal Hearing Screening Program And Measuring Hearing Loss Among Neonates In Dakahlia Governorate, Soheir S. Abou El-Ella, Maha A. Tawfik, Naglaa F. Barseem, Reham M. Abobakr

Menoufia Medical Journal

Objectives

The aim was to evaluate the incidence of hearing impairment among neonates in a rural setup and detect permanent hearing impairment of moderate to severe degree in the frequency range important for speech recognition in neonates, at earliest possible time and help to provide appropriate intervention (medical/surgical/rehabilitation) following the detection of a permanent hearing impairment.

Background

Deafness is the most common curable childhood handicap. It is a well-recognized fact that unidentified hearing impairment can adversely affect optimal speech and language development and therefore academic, social, and emotional development. Universal neonatal hearing screening programs have been implemented in many developed …

Copeptin As A Diagnostic And Prognostic Biomarker For Sepsis In Pediatric Intensive Care Unit, Zein A. Omar, Fady M. El-Gendy, Eman A. Badr, Walaa M. Nabil Ibrahim

Menoufia Medical Journal

Objective

Assessment the role of copeptin as a diagnostic and prognostic biomarker for sepsis in a pediatric intensive care unit (PICU).

Background

Copeptin has been proposed as a promising biomarker for the diagnosis and prognosis of pediatric sepsis in patients with systemic inflammatory response syndrome, sepsis, severe sepsis, and septic shock.

Patients and methods

This prospective case–control study was conducted on 75 patients with sepsis admitted to the PICU of Menoufia University Hospital and 25 healthy controls. All patients are subjected to a detailed history, physical examination, and laboratory investigations. Pediatric Sequential Organ Failure Assessment, Pediatric Risk of Mortality III …

Referral Patterns For Pediatric Sports-Related Concussion In One New England Health Care System, Joseph Benert, Amy Haskins Phd, Christina T. Holt, Krystian Bigosinski

Journal of Maine Medical Center

Introduction: Patients with concussion may benefit from care provided by professionals from multiple disciplines based on the constellation of symptoms being reported. This study analyzed referral patterns from primary care and sports medicine clinicians for pediatric patients with sports-related concussion in one health care system.

Methods: A retrospective chart review identified referrals placed to physical therapy, occupational therapy, speech pathology, optometry, psychology, neuropsychology, audiology, neurology, ophthalmology, otolaryngology, psychiatry, and sports medicine for pediatric patients with sports-related concussion. These patients were evaluated at MaineHealth family medicine, internal medicine/pediatrics, pediatrics, and sports medicine clinics in southern Maine between February 2019 and June …

My Happy Baby Is Back: Zero Balancing, Craniosacral Therapy And A Baby’S Journey To Becoming Mobile, Veronica Quarry

Journal of Transformative Touch

Alison began receiving ZB and CST at 13 months of age due to gross motor delays: at that age she was only able to sit somewhat rigidly. After the first session, Alison changed` from being very unhappy and seemingly frustrated to being happy and more calm. Within one month of weekly sessions, Alison was able to be on her tummy, began to crawl, became more agile in seated play, was squatting and standing and took her first steps.

Clinical And Biomechanical Comparisons Between Youth Pitchers With And Without A History Of Throwing Arm Pain Or Injur, Shayne D. Fehr, Adam E. Hadro, Brian R. Butler, Janelle A. Cross, Gunnar L. Whealy, Derek S. Damrow, Xue-Cheng Liu

ISBS Proceedings Archive

This study aimed to determine if there are clinical and kinematic differences in youth pitchers with a self-reported history of throwing arm pain or injury (PI) to those without (NPI). Forty male baseball pitchers ages 9 to 14 years old were divided into a PI group (n=20) and a NPI group (n=20). Injury history, pitching exposure, subject demographics, range of motion, and strength measurements were collected, along with throwing arm kinematics via a motion capture system. When comparing PI and NPI, significant physical differences were observed, with a greater presence of axillary hair, increased forearm length and decreased shoulder internal …

The Impact Of The Covid-19 Pandemic On The Physical And Mental Health Of School-Aged Children, Syed Azlan Abbas, Sufia Athar, Nadeem Zafar Jilani

HCA Healthcare Journal of Medicine

The SARS-CoV-2 (COVID-19) pandemic caused a deleterious impact on global health. School-aged children were significantly impacted by the pandemic. These impacts may be attributed to the fact that this age group is at a vulnerable developmental stage and is susceptible to profound effects. We conducted a thorough literature review using PubMed, Medline, and Science Direct electronic database searches between 2020-2022. We retrieved 757 studies, 25 of which were included in our review. We considered the impact of the COVID-19 pandemic on the physical and mental health of school-aged children (5-18 years), and the results were analyzed and included in our …

Translation And Cross-Cultural Adaptation Of English Version Of Kiddy-Kindl To Filipino Language In Assessing The Children's Health-Related Quality Of Life (Chrqol), Arlene C. Chiong Maya, Bettina Alessandra B. Mamuric, Joan Paula Y. Pascua, Nathali A. Tigas, Christopher Albert Q. Baylan, Maria Patricia C. Casaclang, Isabela Mariel Z. De Venecia, Lorenzo Miguel L. Gonzales, Gedrich Israel M. Jacob, Shaun Lucas K. Lee, Gabriel C. Lua, Karleen Eve V. Nieva, Socrates P. Pangilinan, Vincent O. Pascual, Andrea Isabelle G. Paule, Mariam Ayesha J. Rodriguez, Codie Lanz I. Sioson, Kate C. Tating, Nicole L. Tigas, Eugene V. Tolentino

Internet Journal of Allied Health Sciences and Practice

Background: Children's health-related quality of life (CHRQoL) involves a child's aim, expectations, standards, or concerns regarding overall health and its domains. The Kiddy-KINDL questionnaire is a tool to measure CHRQoL from information directly derived from children. It has been translated to various languages, except Filipino. This study would provide Filipino healthcare professionals with another functional tool for pediatric evaluation. Objective: To translate the English version of Kiddy-KINDL to Filipino and to determine its validity, test-retest reliability, and internal consistency of the Kiddy-KINDL in assessing the children's health-related quality of life (CHRQoL). Methods: The study involved 3 Phases: Translation, Pilot Testing, …

Pentraxin-3 Levels In Β-Thalassemia Major And Its Relationship With Antioxidant Capacity And Total Oxidant Stress, Farida Hussein El Rashedy, Seham Mohammed Ragab, Ashraf Abd El-Fatah Dawood, Ramy Ashmawy Ahmed El Ashmawy, Mahmoud Ahmed El Hawy

Menoufia Medical Journal

Objectives:to evaluate Pentraxin-3 Levels (PTX-3) in pediatric patients with β-thalassemia major, intermedia and minor and its relationship with antioxidant capacity and total oxidant stress.

Background: PTX-3 increases alongside with oxidant stress. Therefore, it can be used as an early diagnostic marker for inflammation.

Methods:A case control study was conducted on 60 pediatric patients with β-thalassemia enrolled from Pediatric Department, Menoufia University. Another 30age and sex matched healthy children were included as a controlgroup. The study was performed during January 2020 to January 2022.

Results: Pentraxin 3 level was higher in all β. Thalassemia patientscompared with control. Total antioxidant capacity was …

Mortality Rate Risk Factors In Neonatal Intensive Care Units In El Giza Governorate, Ghada M. Elmashad, Shimaa A. Ibrahim, Hanan M. Elsayed

Menoufia Medical Journal

Objective: This study aimed to determine the incidence of neonatal mortality percentage in NICUs in Giza Governorate hospitals for early prediction of the disease.

Background: Neonatal mortality rates defined as death of a live born newborn within the first 28 days vary greatly between countries, even within high-income countries.

Methods: A retrospective study was conducted on 155 Egyptian neonates aged from 1 day up to 4 weeks to evaluate the risk factors of the mortality rates at Giza Governorate hospitals NICU during the period from August 2021 to December 2021.

Results: We reported about 6.5% of the studied neonates experienced …

Relation Between Milk Temperature And Feeding Tolerance In Premature Infants, El-Mashad Gm, El Bastawesy N T M, El Sayed H M

Menoufia Medical Journal

Objectives: To evaluate the effect of milk temperature either at warm temperatures closer to freshly expressed breast milk versus at room temperature on feeding tolerance in premature infants.

Background:

Feeding intolerance (FI) is frequent among preterm infants in neonatal intensive care units (NICUs). It has several symptoms and is attributed to many factors including milk temperature.

Methods:

This prospective cohort study included 70 preterm neonates divided into 2 groups; group I included 35 preterm neonates fed with milk at 22– 24°C, closer to room temperature, group II: 35 preterm neonates fed with milk at 32– 34°C, closer to freshly expressed …

Therapeutic Effect Of Probiotics In Neonatal Physiological Jaundice, Ghada Mohamed El Mashad, Ayatmagdy Mohamed Abo El-Mag, Hanan Mostafa Elsayed

Menoufia Medical Journal

Objectives: The aim was to study the effect of probiotics on physiological jaundice.

Background:

Neonatal jaundice is a relatively prevalent disease. Probiotics supplementation therapy could assist to improve the recovery of neonatal jaundice.

Patients and methods: This study was double blinded randomized clinical trial which was prospectively conducted on 88 neonates admitted to neonatal intensive care units of Menoufia university hospital and Damanhour teaching hospital from January 2022 to April 2022. Infants were allocated into two groups: Probiotic group included 44 full term neonates with physiological jaundice who were given the probiotics and Placebo group included 44 neonates who were …

Everything I Needed To Know To Be A Pediatric Emergency Room Doctor, I Learned As A Waitress, Sarah Gard Lazarus

Patient Experience Journal

When I began my career as a pediatric emergency medicine physician, I believed I was prepared to take on any medical emergency. However, I was not prepared to provide a good patient family experience. Throughout my years of training, I was not taught productive ways of interacting with patients and was unaware of how impactful the patient family experience would be. Negative patient family experience scores affected my interactions with patients, my shared decision making and my ability to provide quality care. After working to improve my scores, I focused on skills I obtained in a non-medical setting, as a …

Does Positive Psychology Coaching Improve Trainee Well-Being? Evidence From A Longitudinal Professional Development Coaching Program In A Cohort Of Pediatric Trainees, Benjamin Nelson, Jacqueline T. Chu, Michael G. Healy, Yoon Soo Park, Kerri Palamara Md

Journal of Wellness

Introduction: Trainee burnout is common and evidence supporting the effectiveness of well-being interventions for this population is limited. We studied the effect of a longitudinal coaching program grounded in positive psychology on measures of pediatric trainee well-being.

Methods: Pediatric interns and fellows (n = 67) were enrolled in a positive psychology coaching program in 2017-2019. Pediatric faculty (n = 23) underwent training and were paired with trainees outside their field of interest. Trainees were surveyed at the beginning and end of the program to assess burnout and well-being, and key skills necessary to achieve well-being.

Results: Thirty-one …

Pediatric Adhd And Screening For Comorbidities, Colleen Kelly

SIU Journal of Medical Science Scholarly Works

Psychiatric disorders are very common in the general pediatric population. Attention Deficit Hyperactivity Disorder (ADHD) is a common psychiatric diagnosis in childhood but can mimic and be found comorbidity with other psychiatric disorders. It is necessary for primary care providers to perform a thorough initial workup for ADHD and possible comorbidity psychiatric disorders to ensure proper diagnosis and treatment of pediatric patients.

Urinary Neutrophil Gelatinase-Associated Lipocalin In Acute Tubular Injury Among Children With Severe Gastroenteritis, Aliaa A. Abdelaziz, Mohamed A. Elrehem Mohamed Soliman, Mostafa A. B. Etman, Sameh A.A Abd Elnaby

Menoufia Medical Journal

Background Acute kidney injury (AKI) is a serious complication in critically ill children. It is a risk factor for mortality, prolonged stays in the ICU, and prolonged mechanical ventilation. Objectives To investigate urinary neutrophil gelatinase-associated lipocalin (NGAL) concentrations as an early biomarker of prerenal AKI in severe dehydrated pediatric patients with acute gastroenteritis. Patients and methods A cross-sectional study was conducted during the period study from August 2020 till March 2021, on 69 children, aged from 1 to 108 months, at the pediatric ICU) of Faculty of Medicine, Menoufia University, after obtaining consent from their parents and caregivers. Results NGAL …

Salivary C-Reactive Protein, Mean Platelet Volume, And Neutrophil-Lymphocyte Ratio As Diagnostic Markers Of Neonatal Sepsis, Hanan M. El-Sayed, Rehab H. El-Arabi, Sara M. El-Deeb, Seham M. Ragab

Menoufia Medical Journal

Background Till now, salivary C-reactive protein (CRP), mean platelet volume (MPV), and neutrophil-lymphocyte ratio (NLR) have not been studied as markers for diagnosis of neonatal sepsis. Objectives To assess the applicability of salivary CRP, MPV, and NLR as diagnostic markers in preterm neonates with neonatal sepsis. Patients and methods A case–control study was conducted on 184 newborns from the neonatal ICU at Menoufia University Hospital and Qwesna General Hospital from 2021 to 2022. All selected newborns were divided into group I, which included 92 neonates diagnosed as having neonatal sepsis, and group II, which included 92 apparently healthy neonates. Full …

Carboxyhemoglobin As An Early Predictor For Pathological Hyperbilirubinemia In Preterm Neonates, Dina A. Midan, Maather K. Elshafie, Noha M. Ashour, Rehab H. Ali Mostafa

Menoufia Medical Journal

Background Hyperbilirubinemia is the most common condition requiring evaluation and treatment in newborns. Approximately 60% of term and 80% of preterm babies develop jaundice in the first week of life. Objectives To assess the role of carboxyhemoglobin (COHb) as an early predictor for pathological hyperbilirubinemia in preterm neonates. Patients and methods This prospective cohort study was conducted on 74 preterm newborns of less than 37 weeks gestation of both sexes, admitted in the first day of life at the neonatal ICU of Menoufia University Hospital from August 2019 to August 2020. All included newborns had serum COHb percentage and total …

Fluid Balance Among Children With Sepsis And Its Relation To Prognosi, Ahmed S. Abo Hola, Mohamed S. Rizk, Nagwan Y. Saleh, Sara S. El-Wazer

Menoufia Medical Journal

Objectives To assess fluid imbalance among critically septic children and its relation to the prognosis of these critically ill children. Background Fluid imbalance is a common adverse event in critically ill children, which may lead to oxygenation failure, mortality, and in bad need for more fluid for resuscitation. Patients and methods This prospective cohort study was conducted on 74 critically septic children admitted into the Pediatric Intensive Care Unit. Pediatric Index of Mortality II, Pediatric Risk of Mortality, and Pediatric Sequential Organ Failure Assessment scores were calculated. Fluid measurements were assessed daily for 5 days. Children were subgrouped regarding the …

Evaluation Of Seroprevalence Of Dengue Virus Infection Among Patients Visiting A Tertiary-Care Center In Indore, Mahmood D. Al-Mendalawi

Menoufia Medical Journal

I refer to the interesting study by Bajpai et al. [1] published in October–December 2021 issue of the Menoufia Medical Journal. Utilizing serology, Bajpai et al. [1] found that 18.4% of the patients admitted to a tertiary‑care center located in Central India were found to be seropositive for dengue disease (DD). We believe that the following methodological limitation related to the serology used in the study could bring into question the rightness of the study results. The impact of that limitation could be explained in dual aspects. On one hand, the laboratory detection of DD is based on serology and …

The Potential Role Of Serum Copeptin Measurement Among Critically Ill Children, Marwa S. Abohola, Mohamed S. Rizk, Muhammad S. El-Mekkawy, Nagwan Y. Saleh

Menoufia Medical Journal

Background Copeptin is a promising biomarker for determining the prognosis of many diseases such as vasopressin-dependent fluid disorders. Objective To assess the role of serum copeptin measurement in critically ill hyponatremic children admitted to the pediatric ICU. Patients and methods This prospective cohort study was conducted on 80 critically ill children and 80 healthy controls. Serum copeptin was measured within the first 24 h of pediatric ICU admission using enzyme-linked immunosorbent assay kits. Results Serum copeptin was significantly elevated among critically ill patients compared with the control group (P < 0.001). There was no significant difference between serum copeptin levels concerning the type of hyponatremia according to volume status, plasma tonicity, or even syndrome of inappropriate antidiuretic hormone secretion diagnosis (P = 0.69, 0.20, and 0.62, respectively). There was no …