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Redox Gene Expression Of Adipose-Derived Stem Cells In Response To Soft Hydrogel, Fahsai Kantawong, Thasaneeya Kuboki, Satoru Kidoaki
Redox Gene Expression Of Adipose-Derived Stem Cells In Response To Soft Hydrogel, Fahsai Kantawong, Thasaneeya Kuboki, Satoru Kidoaki
Turkish Journal of Biology
No abstract provided.
Exogenously Applied Nitric Oxide Confers Tolerance To Salinity-Induced Oxidativestress In Two Maize (Zea Mays L.) Cultivars Differing In Salinity Tolerance, Cengi̇z Kaya, Muhammad Ashraf, Osman Sönmez, Ati̇lla Levent Tuna, Sali̇h Aydemi̇r
Exogenously Applied Nitric Oxide Confers Tolerance To Salinity-Induced Oxidativestress In Two Maize (Zea Mays L.) Cultivars Differing In Salinity Tolerance, Cengi̇z Kaya, Muhammad Ashraf, Osman Sönmez, Ati̇lla Levent Tuna, Sali̇h Aydemi̇r
Turkish Journal of Agriculture and Forestry
No abstract provided.
Silicon-Mediated Oxidative Stress Tolerance And Genetic Variability In Rice(Oryza Sativa L.) Grown Under Combined Stress Of Salinity And Boron Toxicity, Muhammad Ansar Farooq, Zulfiqar Ahmad Saqib, Javaid Akhtar
Silicon-Mediated Oxidative Stress Tolerance And Genetic Variability In Rice(Oryza Sativa L.) Grown Under Combined Stress Of Salinity And Boron Toxicity, Muhammad Ansar Farooq, Zulfiqar Ahmad Saqib, Javaid Akhtar
Turkish Journal of Agriculture and Forestry
The benefits of silicon (Si) in improving crop fitness by biotic and abiotic stress resistance are widely reported. However, investigations about its protective mechanisms for plants facing multiple stresses are very limited. Two contrasting rice cultivars, KS-282 (salt-tolerant) and IRRI-6 (salt-sensitive), were grown in a pot experiment to study the interrelation between Si supplementation (0 and 150 mg kg-1) and boron (B) toxicity (0 and 2.5 mg kg-1) under salinity stress with emphasis on growth response, mineral contents, physiology, and enzymatic antioxidant system response. The results revealed that adverse growth conditions, particularly the combined stress of salinity and B toxicity, …
Organ-Specific Antioxidant Defenses And Ft-Ir Spectroscopy Of Muscles In Crucian Carp (Carassius Auratus Gibelio) Exposed To Environmental Pb2+, Sher Ali Khan, Xiaoyu Liu, Hong Li, Wenting Fan, Bakht Ramin Shah, Jingna Li, Lu Zhang, Suyan Chen, Sher Bahadar Khan
Organ-Specific Antioxidant Defenses And Ft-Ir Spectroscopy Of Muscles In Crucian Carp (Carassius Auratus Gibelio) Exposed To Environmental Pb2+, Sher Ali Khan, Xiaoyu Liu, Hong Li, Wenting Fan, Bakht Ramin Shah, Jingna Li, Lu Zhang, Suyan Chen, Sher Bahadar Khan
Turkish Journal of Biology
Being a nonessential element, lead (Pb2+) can be toxic in trace amounts for freshwater fish. The present study was designed to evaluate the induction of oxidative stress, tissue-specific antioxidant response, acetyl cholinesterase (AchE) activities, and biochemical content of muscle in Crucian carp (Carassius auratus gibelio) after 96 h of acute exposure and 21 days of chronic exposure to various environmental concentrations (5, 10, and 30 µg L-1) of waterborne Pb2+. The results indicated that exposure to 10 and 30 µg L-1 Pb2+ significantly altered the activities of catalase, superoxide dismutase, and glutathione peroxidase in different tissues, while malondialdehyde content increased …
Promotive Effect Of Exogenously Applied Thiourea On Key Physiological Parametersand Oxidative Defense Mechanism In Salt-Stressed Zea Mays L. Plants, Cengi̇z Kaya, Muhammad Ashraf, Osman Sönmez
Promotive Effect Of Exogenously Applied Thiourea On Key Physiological Parametersand Oxidative Defense Mechanism In Salt-Stressed Zea Mays L. Plants, Cengi̇z Kaya, Muhammad Ashraf, Osman Sönmez
Turkish Journal of Botany
A greenhouse experiment was conducted to examine the alleviating role of thiourea (TU) on antioxidants and some vital physiological attributes in salt-stressed plants of two maize cultivars. The maize cv. DK 5783 performed better than cv. Apex 836 in an initial experiment. Of the six TU levels used in the initial experiment, 400 and 500 mg L-1 were chosen for subsequent studies. The two cultivars were subjected to saline stress (100 mM NaCl) and two levels of TU were applied presowing or as foliage spray. Salt stress suppressed total biomass, maximum fluorescence yield (Fv/Fm), chlorophyll, and leaf water potential ($\Psi$w), …
Role Of Melatonin On Calcium Signaling And Mitochondrial Oxidativestress In Epilepsy: Focus On Trp Channels, Mustafa Naziroğlu
Role Of Melatonin On Calcium Signaling And Mitochondrial Oxidativestress In Epilepsy: Focus On Trp Channels, Mustafa Naziroğlu
Turkish Journal of Biology
Calcium ion (Ca2+) accumulation and excessive oxidative stress in the hippocampus and brain cortex have long been known as major contributors to the etiology of epilepsy. I have reviewed the role of Ca2+ signaling through cation channels and mitochondria-mediated oxidative stress on epilepsy in human and animals. A review of the relevant papers and results from recent studies were obtained from PubMed and the Science Citation Index. Current literature findings indicate that melatonin and agomelatine reduce activation of hippocampal transient receptor potential (TRP), glutamate receptors, and voltage-gated calcium channels that are critical for the development of abnormal Ca2+ homeostasis and …
The Effects Of Topical Melatonin On Oxidative Stress, Apoptosis Signals,And P53 Protein Expression During Cutaneous Wound Healing, Azi̇ze Şener, Özge Çevi̇k, Özge Doğan, Nazli Gül Altindi̇ş, Hali̇l Aksoy, Betül Okuyan
The Effects Of Topical Melatonin On Oxidative Stress, Apoptosis Signals,And P53 Protein Expression During Cutaneous Wound Healing, Azi̇ze Şener, Özge Çevi̇k, Özge Doğan, Nazli Gül Altindi̇ş, Hali̇l Aksoy, Betül Okuyan
Turkish Journal of Biology
Elimination of reactive oxygen species (ROS) can be an important strategy to improve healing of wounds. ROS have an effect on proliferation and cell survival signaling, which results in alteration of apoptotic pathways in cells. Melatonin has antioxidant properties on skin wounds. In our study, we investigated the effects of topical melatonin (3%, w/w) on apoptosis and p53 protein expression together with parameters of oxidative stress in a cutaneous excision wound model. Bcl-2 protein levels in wound tissue at the end of days 3, 7, and 14 were significantly increased, while caspase-3 activity and p53 protein expression in wound tissue …
Melatonin Is A Potent Modulator Of Antioxidative Defense And Cellular Proliferation Against Aluminum Toxicity In Rats, Ni̇hal Ömür Bulan, Guner Sarikaya-Unal, Sevim Tunali, Pelin Arda Pi̇ri̇nççi̇, Refiye Yanardag
Melatonin Is A Potent Modulator Of Antioxidative Defense And Cellular Proliferation Against Aluminum Toxicity In Rats, Ni̇hal Ömür Bulan, Guner Sarikaya-Unal, Sevim Tunali, Pelin Arda Pi̇ri̇nççi̇, Refiye Yanardag
Turkish Journal of Biology
Aluminum is the most abundant metal on earth, known for its toxicity to humans and laboratory animals. Melatonin, produced by the pineal gland, has been shown to be an effective antioxidant. In this study, we investigated the possible protective role of melatonin in modulating toxicity and oxidative stress induced by chronic exposure to aluminum in the small intestine of rats. Wistar albino rats were divided into five groups. Group I served as the control and received only physiological saline, Group II served as the control for the melatonin group and received ethanol and physiological saline, Group III received melatonin, Group …
Expression Profiles Of Genes Related To Melatonin And Oxidative Stress In Human Renal Proximal Tubule Cells Treated With Antibiotic Amphotericin B And Its Modified Forms, Joanna Gola, Aleksandra Skubis, Bartosz Sikora, Celina Kruszniewska-Rajs, Jolanta Adamska, Urszula Mazurek, Barbara Strzalka-Mrozik, Grzegorz Czernel, Mariusz Gagos
Expression Profiles Of Genes Related To Melatonin And Oxidative Stress In Human Renal Proximal Tubule Cells Treated With Antibiotic Amphotericin B And Its Modified Forms, Joanna Gola, Aleksandra Skubis, Bartosz Sikora, Celina Kruszniewska-Rajs, Jolanta Adamska, Urszula Mazurek, Barbara Strzalka-Mrozik, Grzegorz Czernel, Mariusz Gagos
Turkish Journal of Biology
Melatonin protects cells from oxidative stress caused by antibiotics. Through the generation of reactive oxygen species (ROS), amphotericin B (AmB) causes oxidative injuries of the kidneys and liver. Generation of oxidized forms of AmB (AmB-ox) in a patient's circulation may also generate ROS, causing side effects. Studies aimed at elimination of toxic properties of AmB are focused on forming complexes of AmB with copper(II) ions (AmB-Cu2+). However, the influence of such modified forms on renal cells and their transcriptome has not been studied so far. Therefore, the aim of this study was to answer the question of whether AmB-Cu2+ complexes …
Melatonin Attenuates Apoptosis And Mitochondrial Depolarization Levels In Hypoxic Conditions Of Sh-Sy5y Neuronal Cells Induced By Cobalt Chloride (Cocl2), Abdülhadi̇ Ci̇hangi̇r Uğuz, Ahmi̇ Öz, Büşra Yilmaz, Seda Altunbaş, Ömer Çeli̇k
Melatonin Attenuates Apoptosis And Mitochondrial Depolarization Levels In Hypoxic Conditions Of Sh-Sy5y Neuronal Cells Induced By Cobalt Chloride (Cocl2), Abdülhadi̇ Ci̇hangi̇r Uğuz, Ahmi̇ Öz, Büşra Yilmaz, Seda Altunbaş, Ömer Çeli̇k
Turkish Journal of Biology
Melatonin (MEL) and its metabolites serve as endogenous reactive oxygen species (ROS) scavengers and have a wide spectrum of antioxidant activity. Cobalt chloride is one of the commonly used hypoxia-mimetic agents, due to blocking the degradation of and triggering the accumulation of hypoxia-inducible factor-1 alpha (HIF-1α ) protein, which is very well known as a critical regulator of the cellular response against hypoxia. In the current study we aimed to determine the possible protective effects of melatonin on a cobalt chloride-induced hypoxia model of SH-SY5Y neuronal cells. Group I was the control group and SH-SY5Y cells were incubated in normal …
Dna Protective And Antioxidative Effects Of Melatonin In Streptozotocin-Induced Diabetic Rats, Seli̇m Sekki̇n, Eda Duygu İpek, Murat Boyacioğlu, Cavi̇t Kum, Ümi̇t Karademi̇r, Hande Sultan Yalinkilinç, Mehmet Onur Ak, Hulki̇ Başaloğlu
Dna Protective And Antioxidative Effects Of Melatonin In Streptozotocin-Induced Diabetic Rats, Seli̇m Sekki̇n, Eda Duygu İpek, Murat Boyacioğlu, Cavi̇t Kum, Ümi̇t Karademi̇r, Hande Sultan Yalinkilinç, Mehmet Onur Ak, Hulki̇ Başaloğlu
Turkish Journal of Biology
Diabetes mellitus is a chronic disease characterized by elevated blood sugar levels. In diabetic patients, oxidative stress induced by the presence of excessive free radicals is closely associated with chronic in?ammation, leading to potential tissue damage. Melatonin (MEL) is a compound synthesized by the pineal gland and a scavenger of free radicals. The aim of this study was to research the effects of MEL on oxidative stress and its DNA protective effects in streptozotocin-induced diabetic rats. In total, 32 rats were equally divided into four experimental groups: control, melatonin, diabetic, and diabetic + melatonin. A single dose of streptozotocin (60 …
Effects Of Photoperiod Variations And Alpha-Lipoic Acid Treatment On Melatonin,Cortisol, And Oxidative Stress Levels In The Blood Of Rats, Cahi̇de Çevi̇k, Recep Aslan
Effects Of Photoperiod Variations And Alpha-Lipoic Acid Treatment On Melatonin,Cortisol, And Oxidative Stress Levels In The Blood Of Rats, Cahi̇de Çevi̇k, Recep Aslan
Turkish Journal of Biology
This study aimed to investigate the effects of frequently changing photoperiods and alpha-lipoic acid treatment on melatonin, cortisol, oxidative markers, and some blood parameters. Eighty-four rats were randomly and equally divided into 7 groups: a control group, 3 prolonged light groups, and 3 prolonged dark groups. The study was completed in 2 stages, with 1- and 4-week periods, respectively. Blood samples were obtained at the end of the first and fourth weeks, and at the end of the dark period for the first and second stages. Serum aspartate aminotransferase and creatinine levels were significantly elevated in the prolonged dark olive …
Ameliorative Role Of Ss-Estradiol Against Lead-Induced Oxidative Stressand Genotoxic Damage In Germinating Wheat Seedlings, Muci̇p Geni̇şel, Hülya Türk, Serkan Erdal, Yavuz Demi̇r, Ebru Genç, İrfan Terzi̇
Ameliorative Role Of Ss-Estradiol Against Lead-Induced Oxidative Stressand Genotoxic Damage In Germinating Wheat Seedlings, Muci̇p Geni̇şel, Hülya Türk, Serkan Erdal, Yavuz Demi̇r, Ebru Genç, İrfan Terzi̇
Turkish Journal of Botany
In the present study, to determine the effects of β-estradiol on the ability of plants to tolerate lead toxicity, β-estradiol (10 μM) and lead (1.75 mM), singly or in combination, were exogenously applied to wheat seeds. Although lead resulted in a marked increase in the activities of antioxidant enzymes, including superoxide dismutase, guaiacol peroxidase, ascorbate peroxidase, and glutathione reductase (but not catalase), as well as an increase in the level of antioxidant compounds such as ascorbic acid and glutathione, this was insufficient to ameliorate the lead-induced oxidative injury or the superoxide anion, hydrogen peroxide, and malondialdehyde levels. However, β-estradiol was …