Digital Commons Network^™

Global Brands And Drivers Of Consumers’ Purchase Behavior: A Multi-Dimensional Perspective, Nayyer Naseem Naseem

Wayne State University Dissertations

As the world moves towards global economic interdependence and international cultural exchanges, more firms are looking towards expansion into overseas markets, to take advantage of emerging business opportunities and available resources. For a firm, that plans to sell its offerings in any foreign market, it is important to understand the consumer behavior and idiosyncrasies predominant in that market, to be more informed, competitive, and successful. Extant research on the dynamics and drivers of consumer’s buying behavior in a global market place has primarily focused, either on the impact of consumers’ personal predispositions, or the influence of brand/product related perceptions, or …

Analysis Of The Secondary Neurodegenerative Consequences Of Primary Oligodendrocyte Stress Through The Use Of The Novel Obiden Mouse Model, Daniel Zdzislaw Radecki

Wayne State University Dissertations

The work of this project was to develop, test and characterize a potential novel mouse model of the neurodegenerative disease Multiple Sclerosis (MS). Historically, MS has been identified as a primary autoimmune disease of the central nervous system (CNS). However, treatments based on this view have met with limited success, and in most cases, fail to prevent progression of MS from mild to moderate and severe forms. Original observations regarding axonal and neuronal pathology in the white and gray matter of the CNS were rediscovered in the 1990s. These observations indicated that even in the absence of the immune system, …

Person-Level Predictors Of Bullying And Bystander Behaviors Of Middle School Students, Todd Jason Dollar

Wayne State University Dissertations

This research examined the ways in which person-level factors (social goals, self-efficacy for defending, moral disengagement, and empathy) influence bullying and bystander experiences of middle school students. Participants (N = 207) in grades 6 to 8 (ages 11- to 15-years-old) who were enrolled in a suburban Public School Academy (i.e., charter school) middle school located in Southeastern Michigan completed a self-report questionnaire on one occasion. Multivariate analysis of variance revealed gender and grade differences in person-level factors. Gender differences were found for victimization. Females experienced significantly more social victimization than males. Multiple regression analyses revealed a synergistic effect for some, …

The Relationship Between The Behaviors Of Students With An Emotional Impairment And The Beginning Of Academic Decline Or Success, Theresa Stephanie Walker

Wayne State University Dissertations

The poor academic and post-secondary outcomes for students with EI have been well documented for decades. Few studies exist, however, that explore where the breakdown in academics begins. Instead of compiling data that adds to this knowledge base, this study explored the academic status of students through multiple data sources. The goal of this was to determine at which level, early elementary, late elementary, middle school, or high school, a breakdown in academics can be detected and at which level interventions should occur. It also attempted to answer the question as to whether or not special education services, specifically a …

The Role Of Individual Character Strengths In Adolescent Academic Achievement And Risky School Behavior, Paul Deschamps

Wayne State University Dissertations

Adolescent achievement is a major developmental task in adolescence and reducing Risky School Behaviors is an important part of the process. Patterns of adolescent achievement and general development are the result of the cumulative process that includes a long history of experience and socialization in school, in the family, in the peer group, and in the community. This study is the first to expand understanding of these key interrelated but unique outcome variables of both Academic Achievement and risky School Behavior through examination of individual Character Strengths in the presence of other key intrapersonal and contextual variables from multiple systems …

Striatal Dopamine Dynamics Upon Manganese Accumulation, Madiha Khalid

Wayne State University Dissertations

STRIATAL DOPAMINE DYNAMICS UPON MANGANESE ACCUMULATION

by MADIHA KHALID

August 2013

Advisor: Dr. Tiffany Mathews

Major: Chemistry (Analytical)

Degree: Doctor of Philosophy

Although manganese (Mn) is fundamental for many biological processes, exposure to excess amounts leads to a neurological disorder termed manganism. Due to its symptomatic similarity to Parkinson's disease, as well its preferential accumulation in dopamine rich brain regions, alterations in the dopamine system are implicated in the onset of manganism. In my research, Mn overexposure is mimicked via subcutaneous administration of manganese chloride to C57BL/6 mice over the course of seven days using a protocol that has been …

The Interictal State In Epilepsy And Behavior, Daniel Tice Barkmeier

Wayne State University Dissertations

Epilepsy is one of the most common neurological diseases, affecting up to 1% of the world population. Epilepsy remains poorly understood and there are currently no medications to cure it. Patients with epilepsy have both seizures as well as another type of abnormal activity between seizures, known as interictal spikes. Interictal spikes have thus far been poorly researched, yet growing evidence supports an important role for them in epilepsy. In this project, we first show the high variability between reviewers in marking interictal spikes on intracranial EEG, and then develop and test an automated detection method to solve this problem. …