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Brunfelsia Hopeana - Pharmacologic Screening: Isolation And Characterization Of Hopeanine, Radhakrishnan Parameswaran Iyer
Brunfelsia Hopeana - Pharmacologic Screening: Isolation And Characterization Of Hopeanine, Radhakrishnan Parameswaran Iyer
University of the Pacific Theses and Dissertations
The genus Brunfelsia (Fam. Solannceae) comprises some 40 species of shrubs native to South Africa and West Indies. Brunfelsia hopeana (common name: Manaca root) and related species are recognized in folk medicine in South America as being useful as diuretic, antirheumatic, antisyphilitic agents and as narcotic hallucinogens. In view of the interesting folkloric uses and a paucity of chemical and pharmacological investigation of B. hopeana, a systematic phytochemical and pharmacological investigation on B. hopeana was undertaken in our laboratory.
Hippocratic screening of the whole root powder and extracts of B. hopeana administered intrapcritonially to rats, indicated that the whole root …