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The Prevalence Of Complementary And Alternative Medicine Use Among Turkish Patientswith Primary Headache, Büşra Sümeyye Arica Polat, Ayşe Çağlar Sarilar Jan 2021

The Prevalence Of Complementary And Alternative Medicine Use Among Turkish Patientswith Primary Headache, Büşra Sümeyye Arica Polat, Ayşe Çağlar Sarilar

Turkish Journal of Medical Sciences

Background/aim: The use of complementary and alternative medicine (CAM) is common in patients with primary headache. However, no study has been reported in which standardized modalities were questioned in a Turkish population. The aim of the present study was to investigate the frequency of CAM use and factors related to it in these patients. Materials and methods: Patients with a diagnosis of primary headache were included in this cross-sectional observational study. Demographic and disease specific characteristics were recorded. The use and effect of 15 CAM modalities were evaluated in accordance with the Traditional and Complementary Medicine Regulations. The patients were …


Wnt Signaling Pathway Activities May Be Altered In Primary Sjogren's Syndrome, Ahmet Karataş, Zühal Ömerci̇koğlu, Burak Öz, Adi̇le Ferda Dağli, Onur Çatak, Fazi̇let Erman, Kazim Şahi̇n, Nevzat Gözel, Süleyman Serdar Koca Jan 2021

Wnt Signaling Pathway Activities May Be Altered In Primary Sjogren's Syndrome, Ahmet Karataş, Zühal Ömerci̇koğlu, Burak Öz, Adi̇le Ferda Dağli, Onur Çatak, Fazi̇let Erman, Kazim Şahi̇n, Nevzat Gözel, Süleyman Serdar Koca

Turkish Journal of Medical Sciences

Background/aim: Sjögren's syndrome (SS) is an autoimmune disease and its pathogenesis is still not completely clear. The wingless (Wnt)/ß-catenin pathway has recently been shown to play an important role in inflammation. This study aims to determine the serum and saliva levels of Dickkopf (DKK)1 and sclerostin and to evaluate Wnt-1 and Wnt-3a expression in the salivary gland in patients with primary SS. Materials and methods: This study included 30 patients diagnosed with SS, 30 patients diagnosed with systemic lupus erythematosus (SLE), and 29 healthy controls. Serum and saliva levels of DKK1 and sclerostin were measured and the expressions of Wnt1 …


Factors Influencing The Length Of Stay In The Palliative Care Unit In Patients Dischargedhome: Results From A Tertiary Hospital In Turkey, Hi̇lal Zengi̇n, İlker Taşçi Jan 2021

Factors Influencing The Length Of Stay In The Palliative Care Unit In Patients Dischargedhome: Results From A Tertiary Hospital In Turkey, Hi̇lal Zengi̇n, İlker Taşçi

Turkish Journal of Medical Sciences

Background/aim: Increased length of stay (LOS) in the palliative care unit (PCU) is a serious burden to the patients and the health care system. The predictors of longer LOS in a PCU have not been reported so far from Turkey. Our aim in this study was to evaluate the factors associated with the LOS in the PCU of a tertiary hospital. Materials and methods: This cross-sectional analysis of a retrospective cohort evaluated adult patients' medical records admitted to the PCU between 2017 and 2019. The main inclusion criteria were 4 or more days of palliative unit stay and being discharged …


The Visceral Adiposity Index, Lipid Accumulation Product, And Plasma Atherogenicindex Are Associated With Subclinical Atherosclerosis In Patients With Newly Diagnosedacromegaly, Mustafa Özbek, Murat Çalapkulu, Sema Hepşen, Muhammed Erkam Sencar, Hayri̇ Bostan, İlknur Öztürk Ünsal, Erman Çakal Jan 2021

The Visceral Adiposity Index, Lipid Accumulation Product, And Plasma Atherogenicindex Are Associated With Subclinical Atherosclerosis In Patients With Newly Diagnosedacromegaly, Mustafa Özbek, Murat Çalapkulu, Sema Hepşen, Muhammed Erkam Sencar, Hayri̇ Bostan, İlknur Öztürk Ünsal, Erman Çakal

Turkish Journal of Medical Sciences

Background /aim: Acromegaly is a rare chronic endocrine disorder, the active form of which is associated with an increased risk of cardiovascular and metabolic disease. Therefore, early diagnosis and treatment of cardiovascular diseases in acromegaly patients are important in terms of morbidity and mortality. The aim of this study was to determine whether the visceral adiposity index (VAI), lipid accumulation product (LAP), and plasma atherogenic index (PAI) are early cardiovascular risk markers in patients with active acromegaly. Materials and methods: The study included 45 patients newly diagnosed with acromegaly and 45 age-sex matched healthy control subjects. The VAI, LAP, and …


Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre Jan 2021

Effects Of The Covid-19 Pandemic On Psychology And Disease Activity In Patients Withankylosing Spondylitis And Rheumatoid Arthritis, Şaki̇r Gica, Yasemi̇n Akkubak, Zaki̇re Kübra Aksoy, Adem Küçük, Erkan Cüre

Turkish Journal of Medical Sciences

Background/aim: The COVID-19 outbreak is known to increase stress levels of most patients with chronic diseases. Patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are highly susceptible to environmental stress. In the current study, we aimed to determine how the COVID-19 pandemic psychologically affected patients with chronic progressive diseases such as AS and RA and the effects of these psychological factors on disease activity. Materials and methods: Age and sex-matched patients with AS (n = 80), RA (n = 80), and healthy controls (n = 80) were included in the study. All participants were evaluated with the "Perceived COVID-19 …


A New Approach To Predicting Shoulder Dystocia: Fetal Clavicle Measurement, Eli̇f Terzi̇ Jan 2021

A New Approach To Predicting Shoulder Dystocia: Fetal Clavicle Measurement, Eli̇f Terzi̇

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the relationship between second- and third-trimester clavicle lengths and birth weight and shoulder dystocia. Materials and methods: This prospective observational study included 181 patients who presented to the Private Etlik Lokman Hekim Hospital for routine pregnancy visits between March 2019 and March 2020. In addition to routine pregnancy examinations, the patients also underwent ultrasonography twice at weeks 20-23 and 33-36 to determine the length of the fetal clavicle. The patients were evaluated for shoulder dystocia in the second stage of labor. The birth weight of the neonates was recorded. The primary objective of this …


The Study Of Tau And Phospho Tau Protein Levels In Attention Deficit And Hyperactivity, Hati̇ce Saraçoğlu, Eser Kiliç, Esra Demi̇rci̇ Jan 2021

The Study Of Tau And Phospho Tau Protein Levels In Attention Deficit And Hyperactivity, Hati̇ce Saraçoğlu, Eser Kiliç, Esra Demi̇rci̇

Turkish Journal of Medical Sciences

Background/aim: Attention deficit and hyperactivity disorder (ADHD) is a widespread neurodevelopmental disorder that begins in childhood and has negative consequences throughout adult life. The etiology and pathogenesis of ADHD are still unclear. Tau protein is a soluble microtubule-related protein expressed by neurons and localized in the cytoplasm as well as axons. Tau protein provides stability of microtubule in two ways: phosphorylation and isoforms. The excessive phosphorylation of Tau separates the protein from the microtubule, thus making it unstable. In this study, we aimed to investigate whether there is a relationship between serum Tau protein and phospho Tau (p-Tau181) levels and …


Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat Jan 2021

Role Of Frailty In Prediction Of Hospitalized Older Adult Patient's Outcomes: A Prospective Study, Maryam Chehrehgosha, Reza Fadaye Vatan, Mahtab Alizadeh Khoei, Farshad Sharifi, Reyhaneh Aminalroaya, Zahra Vahabi, Abolfazl Zendedel, Hamidreza Hekmat

Turkish Journal of Medical Sciences

Background/aim: Frailty is associated with an increased risk of negative short-term and long-term hospital outcomes. This study aimed to evaluate the role of frailty in predicting readmission, length of stay, and quality of life in the hospitalized older adults. Materials and methods: This observational study was conducted at Ziaiyan Hospital, Tehran, Iran. In total, 304 participants (65-85 years), were enrolled through the inclusion criteria from August to December 2019. The frailty index (FI) was assessed by the minimum data set-home care. Readmission was obtained through telephone interviews. The length of stay was gathered by the patient's hospital records, and the …


Dual Energy Ct In Necrotizing Enterocolitis; A Novel Diagnostic Approach, Özgür Çağlar, Emrullah Cesur, Recep Sade, Bi̇nali̇ Firinci, Mustafa Kara, Mehmet Emi̇n Çeli̇kkaya, Akgün Oral, Murat Yi̇ği̇ter, Sevi̇lay Özmen Jan 2021

Dual Energy Ct In Necrotizing Enterocolitis; A Novel Diagnostic Approach, Özgür Çağlar, Emrullah Cesur, Recep Sade, Bi̇nali̇ Firinci, Mustafa Kara, Mehmet Emi̇n Çeli̇kkaya, Akgün Oral, Murat Yi̇ği̇ter, Sevi̇lay Özmen

Turkish Journal of Medical Sciences

Background/aim: Necrotizing enterocolitis (NEC) is one of the most important causes of morbidity and mortality in premature infants. Although there are no specific diagnostic tools, the main factors affecting prognosis are clinical and laboratory findings, and early diagnosis and treatment. In this study, we demonstrate the importance of dual-energy computed tomography (DECT) in confirming intestinal ischemia in neonates with NEC. Materials and methods: Patients diagnosed with NEC in a neonatal intensive care unit were staged according to modified Bell's classification, and DECT was performed on patients with NEC stages 2-A, 2-B and 3-A. According to their DECT reports, these patients …


Biliary Stents Are Forgotten More Frequently In Elderly Patients, Ali̇ Erkan Duman, Hasan Yilmaz, Sadetti̇n Hülagü Jan 2021

Biliary Stents Are Forgotten More Frequently In Elderly Patients, Ali̇ Erkan Duman, Hasan Yilmaz, Sadetti̇n Hülagü

Turkish Journal of Medical Sciences

Background/aim: Plastic biliary stents that remain in situ for more than 12 months, called forgotten biliary stents (FBSs), can cause complications such as cholangitis, stent migration, stent occlusion, and perforation. Materials and methods: The medical records of patients who underwent ERCP procedures from December 2016 to December 2020 were analysed retrospectively. Data on patient characteristics, indications for ERCP and stenting, stent types, stenting duration, complications, and causes of FBSs were obtained from the hospital's database. Results: A total of 48 cases with FBSs were analysed. The mean age (SD) of the patients was 71.23 years (±12.165), the male-to-female ratio was …


Evaluation Of Efficacy And Safety Of Pirfenidone 200 Mg Tablets In Patients With Idiopathicpulmonary Fibrosis In A Real-Life Setting, Necmi̇ye Funda Coşkun, Aykut Çi̇lli̇, İsmai̇l Hanta, Can Sevi̇nç, Ayşe Ödemi̇ş, Ahmet Ursavaş Jan 2021

Evaluation Of Efficacy And Safety Of Pirfenidone 200 Mg Tablets In Patients With Idiopathicpulmonary Fibrosis In A Real-Life Setting, Necmi̇ye Funda Coşkun, Aykut Çi̇lli̇, İsmai̇l Hanta, Can Sevi̇nç, Ayşe Ödemi̇ş, Ahmet Ursavaş

Turkish Journal of Medical Sciences

Background/aim: Phase III trials have demonstrated a significant efficacy and an acceptable safety for pirfenidone in patients having mild to moderate idiopathic pulmonary fibrosis (IPF). Real-life data on the use of pirfenidone 200 mg tablets are limited. This study aimed to investigate the efficacy and safety of pirfenidone 200 mg tablets for the treatment of IPF in a real-life setting. Materials and methods: A retrospective, multicenter study conducted in four university hospitals in Turkey between January 2017 and January 2019. Clinical records of patients diagnosed with mild to moderate IPF and receiving pirfenidone (200 mg tablets, total 2400 mg/day) were …


Cadaver Versus Simulator Based Arthroscopic Training In Shoulder Surgery, Gazi̇ Huri̇, Mert Ruşen Gülşen, Ece Belen Karmiş, Doğaç Karagüven Jan 2021

Cadaver Versus Simulator Based Arthroscopic Training In Shoulder Surgery, Gazi̇ Huri̇, Mert Ruşen Gülşen, Ece Belen Karmiş, Doğaç Karagüven

Turkish Journal of Medical Sciences

Introduction: There are few studies that compare the cadaver dissections with the medical simulators in means of talent improvement. Therefore, the aim of this study is to find out if using cadaver dissections is still the golden standard for surgical training or using the medical simulators in surgery could replace cadaver dissections. Materials and methods: The study is conducted during the European Orthopaedics & Traumatology Education Platform accredited Shoulder Club International Cadaver Course including a number of 34 orthopedics trainees. The participants were randomly divided into two groups to be trained with the simulator (Group 1) and on cadavers (Group …


Evaluation Of Extensively Drug-Resistant Gram-Negative Bacteremia Among Solid-Organtransplant Recipients: A Multicenter Study, Tuğba Yanik Yalçin, Özlem Azap, Adem Köse, Yaşar Bayindir, Eli̇f Muki̇me Saricaoğlu, Güle Çinar, Yeşi̇m Uygun Kizmaz, Ebru Kurşun, Hi̇kmet Eda Alişkan, Ayşe Yasemi̇n Tezer Tekçe, Oya Özlem Eren Kutsoylu, Tufan Egeli̇, Alpay Ari, Yurdagül Albayrak, Hati̇ce Çabadak Jan 2021

Evaluation Of Extensively Drug-Resistant Gram-Negative Bacteremia Among Solid-Organtransplant Recipients: A Multicenter Study, Tuğba Yanik Yalçin, Özlem Azap, Adem Köse, Yaşar Bayindir, Eli̇f Muki̇me Saricaoğlu, Güle Çinar, Yeşi̇m Uygun Kizmaz, Ebru Kurşun, Hi̇kmet Eda Alişkan, Ayşe Yasemi̇n Tezer Tekçe, Oya Özlem Eren Kutsoylu, Tufan Egeli̇, Alpay Ari, Yurdagül Albayrak, Hati̇ce Çabadak

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to evaluate the distribution, sources, clinical features, and mortality rates of bacteremia due to evaluation of extensively drug-resistant (XDR) gram negative among solid-organ transplant (SOT) recipients. Materials and methods: A retrospective study of SOT recipients with bacteremia due to XDR gram-negative pathogens in 11 centers between 2016 and 2018 was conducted. Patients' records were evaluated. Results: Of 171 bacteremia that occurred in 164 SOT recipients, 93 (56.7%) were liver, 46 (28%) kidney, 14 (8.5%) heart, and 11 (6.7%) lung recipients. Bacteremia episodes were recorded in the first year in 63.7% of the patients …


Risk Of Autism Spectrum Disorder In Children With A History Of Hospitalization Forneonatal Jaundice, Gaffari̇ Tunç, Ayla Uzun Çi̇çek, Fati̇h Kiliçbay Jan 2021

Risk Of Autism Spectrum Disorder In Children With A History Of Hospitalization Forneonatal Jaundice, Gaffari̇ Tunç, Ayla Uzun Çi̇çek, Fati̇h Kiliçbay

Turkish Journal of Medical Sciences

Background/aim: Limited research has focused explicitly on the association between neonatal jaundice and autism spectrum disorder (ASD), and inconclusive evidence exists in the literature within this framework. This study aimed specifically to investigate whether neonatal jaundice is a potential risk factor for ASD and whether there is a connection between the types of neonatal jaundice and the severity of ASD. Materials and method: This study involved 119 children with ASD [90 males (75.6%), 29 females (24.4%), mean age: 45.39 ± 11.29 months] and 133 healthy controls [100 males (75.2%), 33 females (24.8%), mean age: 46.92 ± 11.42 months]. Psychiatric disorders …


Lticentered Study On Efficiency Of Noninvasive Ventilation Procedures(Safe-Niv), Ebru Ati̇ke Ongun, Oğuz Dursun, Ayşe Berna Anil, Ümüt Altuğ, Özlem Temel Köksoy, Başaknur Akyildiz, Serkan Özsoylu, Tanil Kendi̇rli̇, Serhan Özcan, Riza Di̇nçer Yildizdaş, İlknur Tolunay, Bülent Karapinar, Mehmet Arda Kilinç, Demet Demi̇rkol Jan 2021

Lticentered Study On Efficiency Of Noninvasive Ventilation Procedures(Safe-Niv), Ebru Ati̇ke Ongun, Oğuz Dursun, Ayşe Berna Anil, Ümüt Altuğ, Özlem Temel Köksoy, Başaknur Akyildiz, Serkan Özsoylu, Tanil Kendi̇rli̇, Serhan Özcan, Riza Di̇nçer Yildizdaş, İlknur Tolunay, Bülent Karapinar, Mehmet Arda Kilinç, Demet Demi̇rkol

Turkish Journal of Medical Sciences

Background/aim: To characterize the clinical course of noninvasive positive pressure ventilation (NIPPV) and high flow humidified nasal cannula ventilation (HFNC) procedures; perform risk analysis for ventilation failure. Material and methods: This prospective, multi-centered, observational study was conducted in 352 PICU admissions (1 month-18 years) between 2016 and 2017. SPSS-22 was used to assess clinical data, define thresholds for ventilation parameters and perform risk analysis. Results: Patient age, onset of disease, previous intubation and hypoxia influenced the choice of therapy mode: NIPPV was preferred in older children (p = 0.002) with longer intubation (p < 0.001), ARDS (p = 0.001), lower respiratory tract infections (p < 0.001), chronic respiratory disease, (p = 0.005), malignancy (p = 0.048) and immune deficiency (p = 0.026). The failure rate was 13.4%. sepsis, ARDS, prolonged intubation, and use of nasal masks were associated with NIV failure (p = 0.001, p < 0.001, p < 0.001, p = 0.025). The call of intubation or re-intubation was given due to respiratory failure in twenty-seven (57.5%), hemodynamic instability in eight (17%), bulbar dysfunction or aspiration in 5 (10.6%), neurological deterioration in 4 (8.5%) and developing ARDS in 3 (6.4%) children. A reduction of less than 10% in the respiration within an hour increased the odds of failure by 9.841 times (OR: 9.841, 95% CI: 2.0021-48.3742). FiO2 > 55% at 6th hours and PRISM-3 >8 …


Evaluation Of Ambulance Calls For Patients Over 65 Years Of Age In İzmir, Turkey: A Twoyear Retrospective Analysis, Ahu Pakdemi̇rli̇, Başak Bayram, Erkan Güvenç, Hülya Elli̇dokuz Jan 2021

Evaluation Of Ambulance Calls For Patients Over 65 Years Of Age In İzmir, Turkey: A Twoyear Retrospective Analysis, Ahu Pakdemi̇rli̇, Başak Bayram, Erkan Güvenç, Hülya Elli̇dokuz

Turkish Journal of Medical Sciences

Background/aim: Analysis of interventions for special patient groups is important for the planning of health services, especially emergency medical services. In this study, we aimed to evaluate emergency medical service (EMS) interventions for the elderly and determine the decisive factors affecting transfer to the hospital of EMS team over 2 years (2017 and 2018) in İzmir. Materials and methods: Records of 112 emergency calls that were made between 2017 and 2018 followed up with interventions for patients aged 65 years and older were obtained from the 112 system. The reasons for the calls, outcomes, possible diagnoses of the patients, differences …


Turkish Validity And Reliability Study Of Type 2 Diabetes Stigma Assessment Scale, Bahar İnkaya, Ezgi̇ Karadağ Jan 2021

Turkish Validity And Reliability Study Of Type 2 Diabetes Stigma Assessment Scale, Bahar İnkaya, Ezgi̇ Karadağ

Turkish Journal of Medical Sciences

Background/aim: Stigma has a high incidence and adversely affects people with diabetes. In this context, patients face difficulties such as fear of losing their jobs, travel restrictions, isolation from social life, problems related to mental health, and feeling of wellness. The aim of this study was to investigate the validity and reliability of the stigma assessment scale in individuals with type 2 diabetes. Materials and methods: The study sample consisted of 153 diabetic individuals. The validity of language, content, and construct were examined to evaluate the validity of the type 2 diabetes stigma assessment scale. Cronbach's alpha was used to …


Does Previous Open Or Percutaneous Renal Stone Surgery Affect Retrograde Intrarenalsurgery Outcomes?, Özer Güzel, İbrahi̇m Can Aykanat, Yilmaz Aslan, Ahmet Asfuroğlu, Meli̇h Balci, Altuğ Tuncel Jan 2021

Does Previous Open Or Percutaneous Renal Stone Surgery Affect Retrograde Intrarenalsurgery Outcomes?, Özer Güzel, İbrahi̇m Can Aykanat, Yilmaz Aslan, Ahmet Asfuroğlu, Meli̇h Balci, Altuğ Tuncel

Turkish Journal of Medical Sciences

Background/aim: Open or percutaneous renal stone surgery can have an adverse effect on the collecting system of the kidney. We evaluated retrograde intrarenal surgery outcomes in patients with 󖼮 mm renal stones who had open or percutaneous renal stone surgery history. Materials and methods: A total of 707 patients who underwent retrograde intrarenal surgery treatment were included in this study. Fifty-six patients had open or percutaneous renal stone surgery history (Group 1) and the remaining did not (Group 2, n = 651). The groups were compared in terms of age, stone size, stone-free rates, and complications. Results: The mean age …


An Investigation Of The Factors That Influence Functional Improvement In Strokerehabilitation, Onur Altuntaş, Serkan Taş, Alp Çeti̇n Jan 2021

An Investigation Of The Factors That Influence Functional Improvement In Strokerehabilitation, Onur Altuntaş, Serkan Taş, Alp Çeti̇n

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to determine effect of age, sex, affected extremity, disability severity, treatment type, cerebrovascular accident (CVA) etiology, number of treatment sessions, and CVA duration on the functional improvement of the stroke patients who participated in a physical medicine and rehabilitation program. Materials and methods: The research sample consisted of 322 stroke patients. Clinical and demographic features including age, sex, affected extremity, disability severity, treatment type, CVA etiology, number of treatment sessions, and CVA duration were recorded. Functional status was evaluated retrospectively by using the functional independence measure (FIM) at admission and discharge. Results: It …


Long Term Neurological Sequela Of Isolated Infarctions According To The Topographicareas Of Thalamus, Aygül Tanti̇k Pak, Zahi̇de Mai̇l Gürkan, Sebahat Nacar Doğan, Yildizhan Şengül Jan 2021

Long Term Neurological Sequela Of Isolated Infarctions According To The Topographicareas Of Thalamus, Aygül Tanti̇k Pak, Zahi̇de Mai̇l Gürkan, Sebahat Nacar Doğan, Yildizhan Şengül

Turkish Journal of Medical Sciences

Background/aim: Thalamus infarctions presented with various clinical findings are considered to be related to classical and variative infarction areas. In our study, we aimed to compare the sequela clinical findings of patients with isolated thalamus infarction according to anatomical areas. Materials and methods: Seventy patients diagnosed with isolated thalamus infarction in our clinic between 2010 and 2020 were included in the study. The infarction areas of the patients were divided into groups by the radiologist, including the variative areas to the classical areas using magnetic resonance imaging. Neurological examinations were performed and recorded. Sequela clinical findings of the groups were …


Serum Chitotriosidase And Ykl-40 In Acute Pancreatitis: Reliability As Prognostic Markerfor Disease Severity And Correlation With Inflammatory Markers, Ece Ünal Çeti̇n, Fati̇h Kamiş, Adi̇l Uğur Çeti̇n, Yavuz Beyazi̇t, Murat Keki̇lli̇ Jan 2021

Serum Chitotriosidase And Ykl-40 In Acute Pancreatitis: Reliability As Prognostic Markerfor Disease Severity And Correlation With Inflammatory Markers, Ece Ünal Çeti̇n, Fati̇h Kamiş, Adi̇l Uğur Çeti̇n, Yavuz Beyazi̇t, Murat Keki̇lli̇

Turkish Journal of Medical Sciences

Background/aim: Chitotriosidase and YKL-40, also called chitinase 3-like protein 1, are homologs of family 18 glycosyl hydrolases, secreted by human macrophages and granulocytes under inflammatory conditions. Although increased levels of chitotriosidase and YKL-40 are linked with several inflammatory diseases, the physiological utility of these two enzymes is still not fully characterized. This study aims to analyse the serum YKL-40 and chitotriosidase levels of acute pancreatitis patients to assess whether their activity correlates with acute pancreatitis and its severity. Materials and methods: Chitotriosidase and YKL-40 levels, along with routine laboratory parameters, were determined from the serum samples of 41 acute pancreatitis …


The Evaluation Of Breast Findings Detected Through Different Visualisation Techniques Inacromegaly Patients ? A Retrospective Study, Pinar Akhanli, Sema Hepşen, Beki̇r Uçan, Hakan Düğer, Hayri̇ Bostan, Muhammed Kizilgül, Muhammed Erkam Sencar, Erman Çakal Jan 2021

The Evaluation Of Breast Findings Detected Through Different Visualisation Techniques Inacromegaly Patients ? A Retrospective Study, Pinar Akhanli, Sema Hepşen, Beki̇r Uçan, Hakan Düğer, Hayri̇ Bostan, Muhammed Kizilgül, Muhammed Erkam Sencar, Erman Çakal

Turkish Journal of Medical Sciences

Background/aim: It is known that the increased growth hormone (GH) and insulin-like growth factor-1 (IGF-1) have mitogenic and antiapoptotic properties in breast cells in acromegaly. Our study aims to evaluate breast findings in patients with acromegaly by comparing them to the control group. Materials and methods: Sixty-one patients followed with acromegaly diagnosis and 180 healthy controls were included in our study. Demographic data, laboratory results, Breast Imaging-Reporting and Data System (BI-RADS) scores, and breast density evaluated via mammography, malign and benign breast lesions evaluated via mammography, breast ultrasonography (USG), and breast magnetic resonance imaging (MRI) of patients were compared to …


Risk Factors Associated With Mortality In Intensive Care Covid-19 Patients: Theimportance Of Chest Ct Score And Intubation Timing As Risk Factors, Veci̇he Bayrak, Nurcan Şentürk Durukan, Ferhan Demi̇rer Aydemi̇r, Begüm Ergan, Naci̇ye Si̇nem Gezer, Oya Özlem Eren Kutsoylu, Ali̇ Necati̇ Gökmen, Yusuf Savran Jan 2021

Risk Factors Associated With Mortality In Intensive Care Covid-19 Patients: Theimportance Of Chest Ct Score And Intubation Timing As Risk Factors, Veci̇he Bayrak, Nurcan Şentürk Durukan, Ferhan Demi̇rer Aydemi̇r, Begüm Ergan, Naci̇ye Si̇nem Gezer, Oya Özlem Eren Kutsoylu, Ali̇ Necati̇ Gökmen, Yusuf Savran

Turkish Journal of Medical Sciences

Background/aim: Coronavirus disease 2019 (COVID-19) is a disease with a high rate of progression to critical illness. However, the predictors of mortality in critically ill patients admitted to the intensive care unit (ICU) are not yet well understood. In this study, we aimed to investigate the risk factors associated with ICU mortality in our hospital. Materials and methods: In this single-centered retrospective study, we enrolled 86 critically ill adult patients with COVID-19 admitted to ICU of Dokuz Eylül University Hospital (İzmir, Turkey) between 18 March 2020 and 31 October 2020. Data on demographic information, preexisting comorbidities, treatments, the laboratory findings …