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Resistin Predicts Ischemia In Myocardial Perfusion Scintigraphy, Mustafa Yildirim, Meli̇h Engi̇n Erkan, Muhammet Aşik, Taner Uçgun, Ayşe Yilmaz, Huri̇ Ti̇lla İlçe, Yusuf Aslantaş, Ramazan Memi̇şoğullari, Serkan Bulur, Ahmet Semi̇h Doğan
Resistin Predicts Ischemia In Myocardial Perfusion Scintigraphy, Mustafa Yildirim, Meli̇h Engi̇n Erkan, Muhammet Aşik, Taner Uçgun, Ayşe Yilmaz, Huri̇ Ti̇lla İlçe, Yusuf Aslantaş, Ramazan Memi̇şoğullari, Serkan Bulur, Ahmet Semi̇h Doğan
Turkish Journal of Medical Sciences
Resistin plays a role in the pathogenesis of coronary artery disease and is related to mortality and morbidity through a number of mechanisms. We hypothesize that plasma resistin levels are increased in the presence of ischemia, as measured by GATED single-photon emission computed tomography myocardial perfusion scintigraphy (SPECT MPS), in comparison with nonischemic subjects. Materials and methods: Fasting intravenous blood samples of patients were drawn before a stress test. An ELISA kit was used for the assays. All patients underwent a technetium 99m-sestamibi GATED SPECT MPS study with a 1-day stress-rest protocol. Images were analyzed visually and patients were assessed …
Possible Metabolic Impact Of Ramadan Fasting In Healthy Men, Mustafa Cumhur Vardarli, Hans-Peter Hammes, İrfan Vardarli
Possible Metabolic Impact Of Ramadan Fasting In Healthy Men, Mustafa Cumhur Vardarli, Hans-Peter Hammes, İrfan Vardarli
Turkish Journal of Medical Sciences
Insulin sensitivity and \beta-cell function during Ramadan fasting in healthy male subjects have not been investigated so far. We assessed the changes of these and other metabolic parameters to judge the potential metabolic benefits of Ramadan fasting. Materials and methods: Twenty-four healthy males of Turkish origin living in Germany, with normal glucose tolerance, participated in this study during Ramadan of 2009; 19 who completed fasting were analyzed. Blood was drawn at sunset after a period of fasting lasting approximately 15 h on days 0, 16, and 30 of Ramadan, as well as 7 and 28 days later. Insulin sensitivity (Homeostasis …
Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak
Is The Combined Use Of Insulin Resistance Indices, Including Adipokines, More Reliable In Metabolic Syndrome?, Bi̇rgül Kural, Orhan Değer, Ci̇hangi̇r Erem, Fulya Balaban Yücesan, Rezzan Ali̇yazicioğlu, Yaşam Barlak
Turkish Journal of Medical Sciences
To determine the levels of adipokines (leptin, adiponectin, resistin, and visfatin) and the indices of insulin sensitivity/resistance, and to examine the relationship among them in patients with metabolic syndrome (MetS). Materials and methods: The study groups included 45 subjects with MetS (31 women/14 men), and 45 sex-and age-matched non-MetS healthy volunteers (31 women/14 men). The levels of adipokines were determined by enzyme-linked immunosorbent assay. Results: The levels of leptin and visfatin were significantly higher in the MetS than in the non-MetS subjects (P < 0.01). There was no difference in adiponectin levels in subjects with and without MetS (P = 0.052). Similarly, resistin did not show any statistically significant difference. A statistically significant positive correlation of leptin with insulin levels was observed, while negative correlations of visfatin levels with age, and resistin levels with the ratio of adiponectin to leptin, were found in the MetS (P < 0.05). The combination of adipokines, insulin resistance-sensitivity parameters, and MetS criteria parameters gave more significant differences than a single parameter. Conclusion: Since the parameters mentioned above might affect, interact with, and/or interfere with each other, the combinations of these parameters might give more reliable results to evaluate the insulin resistance/sensitivity in MetS patients.