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Application Of Survival Analysis Techniques To Probabilistic Assessment Of Fatigue In Steel Bridges, Azam Nabizadehdarabi
Application Of Survival Analysis Techniques To Probabilistic Assessment Of Fatigue In Steel Bridges, Azam Nabizadehdarabi
Theses and Dissertations
The fatigue of engineering materials under repetitive loading is a significant issue affecting the design and durability of components and systems in a variety of engineering-related applications including civil, mechanical, aerospace, automotive, and electronics. Many factors can affect the service life of a component or system under repetitive loading, such as the type of structure, loading, connection details, stress state, peak stress or stress range, surface condition, temperature, and environmental exposure. Currently, there is no comprehensive probabilistic approach that can systematically address all the factors that contribute to fatigue on a single mathematical platform. However, advanced analysis techniques developed for …
Risk And Resistance Factors For Depression And Anxiety Among Youth With Sickle Cell Disease, Laura Reinman
Risk And Resistance Factors For Depression And Anxiety Among Youth With Sickle Cell Disease, Laura Reinman
Theses and Dissertations
Objective: Depression and anxiety are common problems for adolescents with sickle cell disease (SCD). It is important to understand both risk and resiliency factors contributing to psychological outcomes among youth with SCD in order to prevent and effectively treat such problems. To better elucidate contributing factors to depression and anxiety among youth with SCD selected risk and resiliency factors from the risk-and-resistance model adapted for SCD were examined (Barakat, Lash, Lutz, & Nicolaou, 2006). The risk factor of fatigue and resistance/resiliency factors of cognitive appraisal of stress and self-concept are of focus because they have been understudied, and their temporal …
The Regulation Of Skeletal Muscle Fatigue During The Progression Of Cancer Cachexia, Brandon N. Vanderveen
The Regulation Of Skeletal Muscle Fatigue During The Progression Of Cancer Cachexia, Brandon N. Vanderveen
Theses and Dissertations
Cachexia is the unintentional loss of body weight secondary to chronic disease and is prevalent is roughly 50% of cancer patients. The loss of body weight and skeletal muscle mass is reduced functional capacity associated with reduced life quality. The etiology of cachexia is multimodal and complex; however, cachexia has been linked to several systemic (e.g. chronic inflammation, hypogonadism, anemia, insulin resistance) and behavioral (e.g. anorexia, inactivity) changes that can compound to accelerate muscle mass and body weight loss. While several inflammatory cytokines are associated with cachexia’s disease progression, our laboratory has established that Interleukin-6 (IL-6) is a key regulator …