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Theses

Theses/Dissertations

2018

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Polya Db3: A Database Cataloging Polyadenation Sites(Pas) Across Different Species And Their Conservation, Ram Mohan Nambiar Dec 2018

Polya Db3: A Database Cataloging Polyadenation Sites(Pas) Across Different Species And Their Conservation, Ram Mohan Nambiar

Theses

Polyadenation is an important process occurring in the messenger RNA that involves cleavage of 3 end nascent mRNAs and addition of poly(A) tails. For this thesis,I present PolyA DB3 ,a database cataloging cleavage and polyadenylation sites (PASs) in several genomes specifically for human,mouse,rat and chicken. This database is based on deep sequencing data. PASs are mapped by the 3’ region extraction and deep sequencing (3’READS) method, ensuring unequivocal PAS identification. Large volume of data based on diverse biological samples is used to increase PAS coverage and provide PAS usage information. Strand-specific RNA-seq data were used to extend annotated 3’ ends …


Interactions Between Polymer Nanoparticles And Blood Plasma Applied To Drug Delivery Systems, Mark Bannon Dec 2018

Interactions Between Polymer Nanoparticles And Blood Plasma Applied To Drug Delivery Systems, Mark Bannon

Theses

Targeted nanoparticle drug delivery has the potential to replace current forms of cancer therapy with previously unparalleled efficiency. Upon introduction into the human body, nanoparticles exhibit a substantial increase in diameter due to a biomolecular corona formation caused by interactions between blood plasma proteins and the nanoparticles. These interactions must be analyzed and understood for targeted delivery to reach its potential in both feasibility and efficiency.

To study the formation of the protein corona, polystyrene nanoparticles were incubated in vitro in goat blood plasma for 10-minute intervals, diluted to different degrees and then measured to obtain the hydrodynamic diameter of …


Analysis Of 3d Printed Ndfeb Polymer Bonded And Organic Based Magnets, Chimaobi Ibeh Dec 2018

Analysis Of 3d Printed Ndfeb Polymer Bonded And Organic Based Magnets, Chimaobi Ibeh

Theses

Additive manufacturing (AM), or commonly known as 3D printing, has introduced to the manufacturing and commercial sectors novel ways of reducing production times, decreasing material waste, and enabling end products with multi-material configuration and complex geometric designs. From industrial scale to customer-based printers, AM has revolutionized the approach to manufacturing, prototyping, and designing in the field of medical, automotive, aerospace, biomedical, electronics and customizable products. Recently, additive manufacturing has crossed over to the area of applications in magnetism due to the economic push for the miniaturization of electronic and mechanical devices, reduction in production costs and material & design flexibility. …


Icing Thickness Prediction Model For Overhead Transmission Lines, Yue Ming Dec 2018

Icing Thickness Prediction Model For Overhead Transmission Lines, Yue Ming

Theses

Failures in a large electric power system are often inevitable. Severe weather conditions are one of the main causes of transmission line failures. Using the fault data of transmission lines of Shaanxi Power Grid from 2006 to 2016, in conjunction with meteorological information, this paper analyses the relationship between the temporal-spatial distribution characteristics of meteorological disasters and the fault of transmission lines in Shaanxi Province, China.

In order to analyze the influence of micro-meteorology on ice coating, a grey correlation analysis method is proposed. This thesis calculates the grey relational between ice thickness and micro-meteorological parameters such as ambient temperature, …


Amorphous Metal Oxide Semiconductor Thin Film Transistors For Printed Electronics, Mustafa Mohammad Yousef Dec 2018

Amorphous Metal Oxide Semiconductor Thin Film Transistors For Printed Electronics, Mustafa Mohammad Yousef

Theses

There is an acute market need for solution-processable semiconductor inks that can form the essential components of the printed analog and digital circuits. Currently, the industry is migrating beyond simply printing conductive metals for interconnects and embracing higher integration by printing transistors directly on the same substrate. This thesis focuses on investigating solution-processed amorphous indium gallium zinc oxide (IGZO) as a semiconducting channel layer of a field-effect transistor to enable low-cost, large-area printed electronics that are physically flexible and optically transparent. Specifically, we aim to achieve field-effect mobility exceeding 1 cm2/Vs, to overcome the limits faced in existing …


The Use Of Media Technologies In Long-Distance Relationships, Paola P. Soto Herrera Dec 2018

The Use Of Media Technologies In Long-Distance Relationships, Paola P. Soto Herrera

Theses

Communication technologies have helped reduce personal distances and stay connected. This study pursued the following questions: What are the most popular media used to communicate in long-distance relationships? Are those in long-distance relationships more likely to use rich or lean media? Do family, friends, and romantic partners differ in their selection of media? Instant Messaging, social media (Instagram, Facebook, Twitter, Snapchat), telephone (cellular, mobile, or landline), online video chat, online audio chat, SMS, and regular mail were the most used media. Respondents were significantly more likely to use rich media. Romantic partners were more likely than either family or friends …


On The Reversible Effects Of Bias-Stress Applied To Amorphous Indium-Gallium-Zinc-Oxide Thin Film Transistors, Anish Suresh Bharadwaj Dec 2018

On The Reversible Effects Of Bias-Stress Applied To Amorphous Indium-Gallium-Zinc-Oxide Thin Film Transistors, Anish Suresh Bharadwaj

Theses

The role of amorphous IGZO (Indium Gallium Zinc Oxide) in Thin Film Transistors (TFT) has found its application in emerging display technologies such as active matrix liquid crystal display (LCD) and active matrix organic light-emitting diode (AMOLED) due to factors such as high mobility 10-20 cm2/(V.s), low subthreshold swing (~120mV/dec), overall material stability and ease of fabrication. However, prolonged application of gate bias on the TFT results in deterioration of I-V characteristics such as sub-threshold distortion and a distinct shift in threshold voltage. Both positive-bias and negative-bias affects have been investigated. In most cases positive-stress was found to have negligible …


An Application Of Deep-Learning To Understand Human Perception Of Art, Sanjana Kapisthalam Dec 2018

An Application Of Deep-Learning To Understand Human Perception Of Art, Sanjana Kapisthalam

Theses

Eye movement patterns are known to differ when looking at stimuli given a different task, but less is known about how these patterns change as a function of expertise. When a particular visual pattern is viewed, a particular sequence of eye movements are executed and this sequence is defined as scanpath. In this work we made an attempt to answer the question, “Do art novices and experts look at paintings differently?” If they do, we should be able to discriminate between the two groups using machine learning applied to their scanpaths. This can be done using algorithms for Multi-Fixation Pattern …


An Adaptive Inventory Management System For Hospital Supply Chain, Pradeep G. Pai Dec 2018

An Adaptive Inventory Management System For Hospital Supply Chain, Pradeep G. Pai

Theses

In healthcare, delivering high quality care to the patients typically requires significant investment in supply chain management systems. Inventory management is an important part of any supply chain system. Researchers have indicated great potential for optimizing existing healthcare inventory systems, especially within hospitals. With ever changing needs, product prices and policies, managing inventory of products in hospitals becomes difficult. As time progresses, the inventory policies of products become sub-optimal. In this research, we study multiple echelons of a hospital supply chain considering the distributors, to address the need for an efficient and effective hospital inventory management system. We propose a …


Development And Characterization Of Novel Iii-V Materials For High Efficiency Photovoltaics, Zachary Shible Bittner Dec 2018

Development And Characterization Of Novel Iii-V Materials For High Efficiency Photovoltaics, Zachary Shible Bittner

Theses

Photovoltaics (PV) are an enabling technology in the field of aerospace, allowing satellites to operate far beyond the technological limitations of chemical batteries by providing a constant power source. However, launch costs and payload volume constraints result in a demand for the highest possible mass and volume specific power generation capability, a proxy for which is device power conversion efficiency. Enhancing the efficiency of III-V PV devices beyond the single-junction Shockley Queisser (SQ) limit has been a driving goal in PV development. Two competing loss mechanisms are thermalization, where photon energy in excess of the absorbing material’s bandgap is lost …


Equitable Pricing Of Episodes Of Care In A Cluster-Based Bundled Payment System, Bikram P. Singh Dec 2018

Equitable Pricing Of Episodes Of Care In A Cluster-Based Bundled Payment System, Bikram P. Singh

Theses

Most of the individuals in the United States are concerned about healthcare affordability and rising healthcare costs. The prevalent healthcare cost reimbursement system, Fee-For-Service (FFS) has been deemed as a key driver for increasing healthcare costs. Bundle payments (BP) has been suggested as an alternative to replace FFS and has shown to reduce the rising healthcare costs. Under BP, the expected set of services involved in treating a diagnosis, or episode of care, is reimbursed by a single payment. We propose a systemic pricing of multiple diagnosis under a Cluster-Based Bundle Payment system (CBBP), where for a given diagnosis, groups …


Exploring The Supply Side Of Food And Beverage Festivals In Saudi Arabia, Mossa Ahmed Haressy Dec 2018

Exploring The Supply Side Of Food And Beverage Festivals In Saudi Arabia, Mossa Ahmed Haressy

Theses

Recently, the Kingdom of Saudi Arabia (KSA) announced its intention to begin implementing a tourist visa regime to streamline entry of tourists into the country and, therefore, attract more international visitors. Food and Beverage festivals (F&B) are targeted as a crucial part of the events sector in Saudi Arabia as they align well with agricultural traditions and Middle East culture to attract both domestic and foreign tourist. The aim of this study was to explore the characteristics, management, and goals of F&B festivals in Saudi Arabia. F&B event organizers were utilized to collect data regarding seven established F&B festivals that …


Properties Of Mixing Sac Solder Alloys With Bismuth-Containing Solder Alloys For A Low Reflow Temperature Process, Tayler John Swanson Dec 2018

Properties Of Mixing Sac Solder Alloys With Bismuth-Containing Solder Alloys For A Low Reflow Temperature Process, Tayler John Swanson

Theses

The subject of extensive research has been the establishing of lower temperature soldering of electronic assemblies that are similar to the once common yet still preferred eutectic Tin-Lead (SnPb) soldering manufacturing processes that are below 217˚C. This research opportunity will contribute data on mixed solder alloy assemblies that can be formed at lower process temperatures. There are many environmental and economic benefits of avoiding the current reliability concerns of assembling electronics at the standard high temperatures which peak at 230˚C 260˚C. To reduce this temperature the use of Bismuth containing solder pastes are mixing with the standard high temperature SAC …


Increasing Revenue By Applying Machine Learning To Congestion Management In Sdn, Nabarun Jana Dec 2018

Increasing Revenue By Applying Machine Learning To Congestion Management In Sdn, Nabarun Jana

Theses

With the advent of 5G, IoT and 4k videos, online gaming, movie streaming and other data intensive applications, the demand for data is sky rocketing. Due to this surge in data, the load on the network increases. This heightened network load causes degradation in network performance. Which can lead to the customer Service Provider (CSP)s loosing revenue if the Service Level Agreement (SLA) are not met.

This report describes how machine learning techniques such as tit for tat can be applied to telecom networks. Machine learning applied to telecom networks help detect congestion and maintain SLAs while increasing yield (revenue). …


A Method For Use Phase Definition As Integrated Into An Object-Oriented Approach To Life Cycle Assessment, Alissa Marie Santucci Dec 2018

A Method For Use Phase Definition As Integrated Into An Object-Oriented Approach To Life Cycle Assessment, Alissa Marie Santucci

Theses

As global environmental concerns increase, industries continue to respond prominently to meeting sustainable practice standards through technological innovations and new business models. However, current sustainability measurement tools, including Life Cycle Assessment (LCA), do not provide practitioners with sufficiently standardized methodology, which leads to uncertainty and limited comparability of results. This research develops a systematic Object-Oriented LCA method to define and quantify the consumed life of a product system during the use scenario under analysis. In this method, the Cumulative Damage Function (CDF) quantifies the consumed life of a product by using inputs of total efficiency or damage, scaling parameters and …


Automatic Modulation Classification Using Cyclic Features Via Compressed Sensing, Andrew J. Ramsey Dec 2018

Automatic Modulation Classification Using Cyclic Features Via Compressed Sensing, Andrew J. Ramsey

Theses

Cognitive Radios (CRs) are designed to operate with minimal interference to the Primary User (PU), the incumbent to a radio spectrum band. To ensure that the interference generated does not exceed a specific level, an estimate of the Signal to Interference plus Noise Ratio (SINR) for the PU’s channel is required. This can be accomplished through determining the modulation scheme in use, as it is directly correlated with the SINR. To this end, an Automatic Modulation Classification (AMC) scheme is developed via cyclic feature detection that is successful even with signal bandwidths that exceed the sampling rate of the CR. …


Transcriptome-Wide Analysis Of Vsv Strains With Varying Ability To Block Nf-Κb, Thomas M. Russell Dec 2018

Transcriptome-Wide Analysis Of Vsv Strains With Varying Ability To Block Nf-Κb, Thomas M. Russell

Theses

Vesicular stomatitis virus (VSV) is a negative sense, single-stranded RNA (ssRNA) virus that is currently studied for its uses as a vaccine viral vector and its potential in oncolytic therapy. The M protein of VSV is the active participant in the virus’s abrogation of the host innate immune response. This activity is thought to be due to the M protein’s ability to downregulate overall host transcription by blocking nuclear transport. A VSV mutant containing a D52G mutation in the M protein (22-20) has been shown to block nuclear transport while being defective as a suppressor of NF-κB activation. It is …


Eazytrack: Exploring Next-Gen Technology And User Experience Design To Help Relieve Stress, Kaiyi Dong Dec 2018

Eazytrack: Exploring Next-Gen Technology And User Experience Design To Help Relieve Stress, Kaiyi Dong

Theses

In this competitive society with the pace of people’s life speeding up, stress is inevitable. Too much stress though will bring negative effects on people’s physical and emotional wellbeing. According to a survey the American Psychological Association conducted from 2007 to 2016, very few actions are being taken to prevent or relieve stress effectively even though an increasing number of people have realized that stress has an impact on health and wellbeing.¹ Untreated chronic stress can contribute to severe health problems including anxiety, insomnia, muscle pain, high blood pressure, and a weakened immune system.² Today, there are many stress trackers …


Automatic Trellis Generation For Demodulation Of Faster Than Nyquist Signals, Deepan Govindaraj Dec 2018

Automatic Trellis Generation For Demodulation Of Faster Than Nyquist Signals, Deepan Govindaraj

Theses

Mobile communication has become one of the most important and fast developing technology in the past couple of decades. Future of telecommunication raises a high demand for higher data rate and system capacity. There are plenty of researches taking place across the world to provide a better service. One such research is Faster than Nyquist signaling and it has grabbed the attention of many researchers in the recent past. In digital communication implemented using Nyquist pulses, the pulse rate is upper-bounded by twice the channel bandwidth. Signaling above this rate results in the loss of pulse orthogonality and introduces ISI. …


Poly(Lactic Acid) (Pla), Poly(-Caprolactone) (Pcl) And Thermoplastic Starch (Tps) Blends For Compostable Packaging Applications, Rui Wang Dec 2018

Poly(Lactic Acid) (Pla), Poly(-Caprolactone) (Pcl) And Thermoplastic Starch (Tps) Blends For Compostable Packaging Applications, Rui Wang

Theses

The increasing severe plastic issue has brought the biodegradable polymers into the top researching field. The various bioplastics become a promising way to reduce the solid waste and boost the sustainable development of the world. This study focused on the performance of ternary blend of PLA, PCL and TPS. All these three materials are playing an essential role in the bioplastic industry due to their outstanding properties and 100% biodegradable. However, the drawbacks of each material limited its application in packaging. This study aimed to overcome the shortcomings by blending PLA, PCL and TPS in an optimal composition, and proper …


Sense - Recommendation System Based On Affective Interpretations Of Social Media Posts: A Proposed User Interface Design, Zheng Zhang Dec 2018

Sense - Recommendation System Based On Affective Interpretations Of Social Media Posts: A Proposed User Interface Design, Zheng Zhang

Theses

It is now easier and cheaper for people to get involved in technology, and most people are obtaining or receiving tons of information nowadays, such as recommendations. Different recommendations are filled with our devices like smartphones, tablets or even wearable devices. However, most searches and recommendation systems fail to take into consideration the emotional context related to a user’s input and action, and as a consequence, people can hardly receive personalized, emotion-related, user-based recommendations. Though people are given various choices about lives based on searches and saved data, those recommendations can hardly improve the stress and difficulties of accomplishing daily …


Vr Interactive Prototype: The Future Wardrobe. Explore Vr Interaction Design For The Sense Of Presence Enhancement Through An Immersive Vr Installation, Jing Lyu Dec 2018

Vr Interactive Prototype: The Future Wardrobe. Explore Vr Interaction Design For The Sense Of Presence Enhancement Through An Immersive Vr Installation, Jing Lyu

Theses

Virtual Reality (VR) is a new platform that provides the public with an immersive experience in a virtual space. With the development and promotion of VR hardware devices, virtual reality technology is applied in various industries such as the advertising of products, traveling, game, art, therapy, education and many others. Unlike media such as videos and pictures, VR applications allow users to interact with content instead of only watching. Beyond the novelty of the technology, for a meaningful immersive experience, VR interaction design and visual design must work together to place the user in a natural and comfortable state. The …


Predictive Models In Brain Connectivity Analysis, Guenadie Nibbs Dec 2018

Predictive Models In Brain Connectivity Analysis, Guenadie Nibbs

Theses

Neuroscience have been the field with most significant contributions to the study of the human brain. The development of new techniques for image acquisition has made possible the improvement of extracting quality information of brain activity. Utilizing functional MRIs, is possible to measure brain activity based on changes of the oxygen level in the blood at certain period of time. This imaging data is transformed into numerical values using a software that maps all the information into a data object. Taking advantage of the availability of functional connectivity information of the human brain, the present study shows a widespread process …


Try To Remember Breath, Rita Chapman Dec 2018

Try To Remember Breath, Rita Chapman

Theses

A collection of original poems.


Residents' Attitudes Toward A Proposed Tourism Development In Jeddah City In Saudi Arabia, Mohammed Basendwah Dec 2018

Residents' Attitudes Toward A Proposed Tourism Development In Jeddah City In Saudi Arabia, Mohammed Basendwah

Theses

Residents agreement toward tourism development is crucial for the tourism industry to succeed. In 2013, the Saudi Arabia government formed the 2030 vision, which aims to invest in tourism and minimize the exporting of oil as a source of income. Many tourism investments in Saudi Arabia have begun specifically in the city of Jeddah. The purpose of this study is to identify the residents’ perception toward the proposed tourism development in Jeddah. Unlike most of the study, the residents’ perception will be measured before the tourism development plan takes a place.


Lone: An Interactive Mobile Application Introducing An Authentic Shopping Experience. Discover Joys Of The World, Experience Authentic Shopping., Xi He Dec 2018

Lone: An Interactive Mobile Application Introducing An Authentic Shopping Experience. Discover Joys Of The World, Experience Authentic Shopping., Xi He

Theses

LONE is an interactive mobile application, which introduces an authentic international shopping experience, helps customers to buy authentic products from a small store in another country. Based on the survey of usage of cross-border e-commerce in selected countries done by United Nations Conference on Trade and Development and Statista, today’s customers have higher demands on traveling and purchasing authentic products from overseas ever than before. Since the majority of them don’t have the time or budget of going around the world, people buying authentic items from other places become one of the sources for people to get to understand about …


Statistical Aspects Of Music Mining: Naive Dictionary Representation, Qiuyi Wu Dec 2018

Statistical Aspects Of Music Mining: Naive Dictionary Representation, Qiuyi Wu

Theses

Extensive studies have been conducted on both musical scores and audio tracks of western classical music with the finality of learning and detecting the key in which a particular piece of music was played. Both the Bayesian Approach and modern unsupervised learning via latent Dirichlet allocation have been used for such learning tasks. In this research work, we propose and develop the novel idea of treating musical sheets as literary documents in the traditional text analytics parlance, to fully benefit from the vast amount of research already existing in statistical text mining and topic modeling.

We specifically introduce the idea …


Modeling And Extraction Of Transport Parameters To Simulate Drug Delivery In The Murine Cochlea, Kevin Wilson Dec 2018

Modeling And Extraction Of Transport Parameters To Simulate Drug Delivery In The Murine Cochlea, Kevin Wilson

Theses

The usage of 1D and 3D models to simulate drug transport through the inner ear is a prominent method in cochlear fluid pharmacokinetics. However, the data used to create these models, is often based on invasive sampling methods that limit the spatial resolution given the size of the cochlear compartments within which solute can be measured. In this work by leveraging 3-D registered micro-Computed Tomography (μCT) scans of the murine cochlea that have been taken as iodinated contrast agent is delivered to it, we extract transport parameters and simulate a forward 1D model that allows variable and pulsatile delivery profiles …


Id: An Animation With An Environment About The Ego And The Id, Huangzhi Tang Dec 2018

Id: An Animation With An Environment About The Ego And The Id, Huangzhi Tang

Theses

When people discover their inner worlds, they would feel different psyches inside. According to the human psyche conception of Sigmund Freud, there are three kinds of psyches in human minds. They are the id, ego, and super-ego, representing instinct, reality, and morality.

What is worth noticing is the relationship between the ego and id. While the ego is the part people know most because it is generally conscious, the id is the most mysterious, because it is enormous and completely subconscious. Also, they talk because the ego is a

mediator between the id and the real world. However, while the …


Atmosphere Of An Explosion, Sarah Kinard Dec 2018

Atmosphere Of An Explosion, Sarah Kinard

Theses

The thesis work explores the impact of an abusive environment and in what ways that abuse influences and directs an individual's state of mind. My creative exploration comes from my intimate, personal childhood memories and experiences. Working through the influences that the cycle of trauma creates, led me to the use of a variety of materials to focus in a singular voice in this body of work. I developed a symbolic and emotive visual vocabulary that speaks about how I have been shaped both spiritually and emotionally, through my exposure and my journey of self-healing. I will discuss in this …