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A Comprehensive Assessment On Coumarin–Thiazole Composite As A Versatile Scaffold For The Potent Multifunctional Bioactive Agents, Swethan Babu Ravi, Muthu Kumaradoss Kathiravan
A Comprehensive Assessment On Coumarin–Thiazole Composite As A Versatile Scaffold For The Potent Multifunctional Bioactive Agents, Swethan Babu Ravi, Muthu Kumaradoss Kathiravan
The Thai Journal of Pharmaceutical Sciences
In the discovery of new drugs, the molecular hybridization approach has emerged as a promising strategy as a multitargeted approach to prevent, treat, and address drug resistance and unmet needs. Several hybrid molecules are currently under various stages of clinical trials and could be implemented into clinical practice shortly to treat various diseases. In such purview, thiazole and coumarins play an essential role due to their diverse biological activities in medicinal chemistry. The hybridization approach of these two potential pharmacophores may lead to the discovery of newer drug candidates with a more comprehensive therapeutic application with multiple mechanisms of action. …
Recent Advancements On Biological Activity Of Indole And Their Derivatives: A Review, Punet Kumar, Md Iftekhar Ahma, Sangam Singh, Mohammad Rizki Fadhil Pratam, Arun K. Mishra
Recent Advancements On Biological Activity Of Indole And Their Derivatives: A Review, Punet Kumar, Md Iftekhar Ahma, Sangam Singh, Mohammad Rizki Fadhil Pratam, Arun K. Mishra
The Thai Journal of Pharmaceutical Sciences
Indole, a versatile outstanding heterocyclic compound, engaged in numerous pharmacological properties due to their multiple biochemical processes. The remarkable indole moiety resembles with numerous protein structures. The fascinating molecular framework of indole makes its suitable for drug development. Indole derivatives mimic the peptides structure and bind reversibly to several enzymes, which contribute enormous opportunities to develop novel drugs with distinct mechanism of action. The presence of nitrogen-based heterocycles in several compounds has been investigated enormously as the core structures comprise several biologically appropriate molecules found active in different diseases. The investigations conducted worldwide have shown outstanding impact for scientists, working …
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
The Thai Journal of Pharmaceutical Sciences
Purpose: The objective of the present study is to assess the antimicrobial activity of gastroretentive formulation for moxifloxacin HCl and in vitro antimicrobial evaluation using the cup-plate method. Materials and Methods: Gastroretentive floating tabl.
Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung
Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung
The Thai Journal of Pharmaceutical Sciences
The objectives of this descriptive study were to study the antimicrobial utilization, type and susceptibility of pathogens, and drug therapy problems (DTPs) in nosocomia-infected patients at Ratchaburi hospital from August 1st to December 31st, 2002. Two...
The Development Of Dermatological Products From Some Thai Medicinal Plants; Part I. Family Labiatae, Siriporn Okonogi, Yanee Pongpaibul, Isamu Murakoshi, Toshikazu Sekine
The Development Of Dermatological Products From Some Thai Medicinal Plants; Part I. Family Labiatae, Siriporn Okonogi, Yanee Pongpaibul, Isamu Murakoshi, Toshikazu Sekine
The Thai Journal of Pharmaceutical Sciences
A comparative study of antimicrobial activities of Coleus amboinicus (I), Anisomeles indica (II), Ocimum sanctum (III), Ocimum basilicum (IV), and Mentha merdinah (V) have been carried out. The ethanol extracts and the essential oils obtained from these ...