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Repeated Intracarotid Amobarbital Tests, T. Loddenkemper, H. H. Morris, Tara T. Lineweaver, C. Kellinghaus

Tara T. Lineweaver

Rationale:Our goal was to determine the frequency of repeated intracarotid amobarbital test (IAT) at our center and to estimate the retest reliability of the IAT for both language and memory lateralization. Methods: A total of 1,249 consecutive IATs on 1,190 patients were retrospectively reviewed for repeat tests. Results: In 4% of patients the IAT was repeated in order to deliver satisfactory information on either language or memory lateralization. Reasons for repetition included obtundation and inability to test for memory lateralization, inability to test for language lateralization, no hemiparesis during first test, no aphasia during first test, atypical vessel filling, and …

Memory Performance Is Related To Language Dominance As Determined By The Intracarotid Amobarbital Procedure, S. Kovac, G. Möddel, J. Reinholz, A. Alexopoulosa, T. Syed, S. Schuele, Tara Lineweaver, T. Loddenkemper

Tara T. Lineweaver

Objective

The goal of this study was to explore the relationship between language and memory lateralization in patients with epilepsy undergoing the intracarotid amobarbital procedure.

Methods

In 386 patients, language lateralization and memory lateralization as determined by laterality index (LI) were correlated with each other.

Results

Language lateralization and memory lateralization were positively correlated (r = 0.34, P < 0.01). Correlations differed depending on the presence and type of lesion (χ² = 7.98, P < 0.05). LIs correlated significantly higher (z = 2.82, P < 0.05) in patients with cortical dysplasia (n = 41, r = 0.61, P < 0.01) compared with the group without lesions (n = 90, r = 0.16, P > 0.05), with patients with hippocampal sclerosis falling between these two groups. Both memory (P < 0.01) and language (P …