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Public Health Theses

2020

Children

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Predictors Of Tb-Mortality Among Hospitalized Hiv-Infected Children In Kenya, Henry Sohre Kitiabi Mr., Lisa Marie Cranmer Dr. May 2020

Predictors Of Tb-Mortality Among Hospitalized Hiv-Infected Children In Kenya, Henry Sohre Kitiabi Mr., Lisa Marie Cranmer Dr.

Public Health Theses

Abstract

Background: Tuberculosis (TB) is a bacterial disease caused by Mycobacterium tuberculosis, resulting in an estimated one million new cases and over 200,000 deaths annually among children. TB is the leading cause of death in HIV-infected children globally (Swaminathan & Rekha, 2010), but few studies have evaluated cofactors of pediatric TB mortality the era ART. We evaluated predictors of TB mortality in a cohort of HIV-infected hospitalized Kenyan children initiating antiretroviral therapy (ART).

Methods: HIV-infected children age(PUSH) trial. Children were ART-naïve and started ART within 2 weeks of enrollment. All children underwent intensified TB case finding at enrollment and were …