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Impact Of A Reduced Nicotine Standard On Young Adult Appeal For Menthol And Non-Menthol Cigarettes, Amy M. Cohn, Rachel Cassidy, Rachel Denlinger-Apte, Eric Donny, Andrea C. Villanti, Dorothy Hatsukami, Delaney Dunn, Riley Wyatt, Taylor Niznik, Tamar Cohen-Davidyan, Michael Smith, Sarah J. Ehlke
Impact Of A Reduced Nicotine Standard On Young Adult Appeal For Menthol And Non-Menthol Cigarettes, Amy M. Cohn, Rachel Cassidy, Rachel Denlinger-Apte, Eric Donny, Andrea C. Villanti, Dorothy Hatsukami, Delaney Dunn, Riley Wyatt, Taylor Niznik, Tamar Cohen-Davidyan, Michael Smith, Sarah J. Ehlke
Psychology Faculty Publications
Introduction The Food and Drug Administration (FDA) announced its intention to reduce the nicotine content in cigarettes as a strategy to promote cessation and reduce smoking-related harm. A low nicotine product standard will apply to all cigarettes on the market, including menthol cigarettes. In December 2021, the FDA approved a modified risk tobacco product application for menthol and non-menthol flavoured very low nicotine cigarettes (VLNC) from the 22nd Century Group. Notably, experimentation with menthol cigarettes is linked to smoking progression, as well as greater nicotine dependence relative to non-menthol cigarette use. If menthol VLNCs are perceived as more appealing than …
Promoting Healthy Decision-Making Via Natural Environment Exposure: Initial Evidence And Future Directions, Meredith S. Berry, Meredith A. Repke, Alexander L. Metcalf, Kerry Jordan
Promoting Healthy Decision-Making Via Natural Environment Exposure: Initial Evidence And Future Directions, Meredith S. Berry, Meredith A. Repke, Alexander L. Metcalf, Kerry Jordan
Psychology Faculty Publications
Research within psychology and other disciplines has shown that exposure to natural environments holds extensive physiological and psychological benefits. Adding to the health and cognitive benefits of natural environments, evidence suggests that exposure to nature also promotes healthy human decision-making. Unhealthy decision-making (e.g., smoking, non-medical prescription opioid misuse) and disorders associated with lack of impulse control [e.g., tobacco use, opioid use disorder (OUD)], contribute to millions of preventable deaths annually (i.e., 6 million people die each year of tobacco-related illness worldwide, deaths from opioids from 2002 to 2017 have more than quadrupled in the United States alone). Impulsive and unhealthy …
Stress-Induced Executive Dysfunction In Gdnf-Deficient Mice, A Mouse Model Of Parkinsonism, Mona Buhusi, Kaitlin Olsen, Benjamin Z. Young, Catalin V. Buhusi
Stress-Induced Executive Dysfunction In Gdnf-Deficient Mice, A Mouse Model Of Parkinsonism, Mona Buhusi, Kaitlin Olsen, Benjamin Z. Young, Catalin V. Buhusi
Psychology Faculty Publications
Maladaptive reactivity to stress is linked to improper decision making, impulsivity, and discounting of delayed rewards. Chronic unpredictable stress alters dopaminergic function and re-shapes dopaminergic circuits in key areas involved in decision making, and impairs prefrontal-cortex dependent response inhibition and working memory. Glial-derived neurotrophic factor (GDNF) is essential for regulating dopamine release in the basal ganglia and the survival of dopaminergic neurons, and GDNF-deficient mice are considered an animal model for aging-related Parkinsonism. Recently, GDNF expression in the striatum has been linked to resilience to stress. Here we investigated the effects of chronic unpredictable stress on decision making in GDNF-heterozygous …
Stress Alters The Discriminative Stimulus And Response Rate Effects Of Cocaine Differentially In Lewis And Fischer Inbred Rats, Therese A. Kosten, Mindy Miserendino
Stress Alters The Discriminative Stimulus And Response Rate Effects Of Cocaine Differentially In Lewis And Fischer Inbred Rats, Therese A. Kosten, Mindy Miserendino
Psychology Faculty Publications
Stress enhances the behavioral effects of cocaine, perhaps via hypothalamic-pituitary-adrenal (HPA) axis activity. Yet, compared to Fischer 344 (F344) rats, Lewis rats have hyporesponsive HPA axis function and more readily acquire cocaine self-administration. We hypothesized that stress would differentially affect cocaine behaviors in these strains. The effects of three stressors on the discriminative stimulus and response rate effects of cocaine were investigated. Rats of both strains were trained to discriminate cocaine (10 mg/kg) from saline using a two-lever, food-reinforced (FR10) procedure. Immediately prior to cumulative dose (1, 3, 10 mg/kg cocaine) test sessions, rats were restrained for 15-min, had 15-min …