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Paediatrics Publications

2013

Myocardial infarction

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Intra-Thoracic Fat Volume Is Associated With Myocardial Infarction In Patients With Metabolic Syndrome, Umjeet S. Jolly, Abraam Soliman, Charles Mckenzie, Terry Peters, John Stirrat, Immaculate Nevis, Matthew Brymer, Tisha Joy Sep 2013

Intra-Thoracic Fat Volume Is Associated With Myocardial Infarction In Patients With Metabolic Syndrome, Umjeet S. Jolly, Abraam Soliman, Charles Mckenzie, Terry Peters, John Stirrat, Immaculate Nevis, Matthew Brymer, Tisha Joy

Paediatrics Publications

Background: Visceral adiposity is increased in those with Metabolic Syndrome (MetS) and atherosclerotic disease burden. In this study we evaluate for associations between intra-thoracic fat volume (ITFV) and myocardial infarction (MI) in patients with MetS. Methods. Ninety-four patients with MetS, MI or both were identified from a cardiovascular CMR clinical registry. MetS was defined in accordance to published guidelines; where-as MI was defined as the presence of subendocardial-based injury on late gadolinium enhancement imaging in a coronary vascular distribution. A healthy control group was also obtained from the same registry. Patients were selected into the following groups: MetS+/MI- (N = …


Comparison Of The Myocardial Clearance Of Endothelial Progenitor Cells Injected Early Versus Late Into Reperfused Or Sustained Occlusion Myocardial Infarction, Andrea J. Mitchell, Eric Sabondjian, Kimberley J. Blackwood, Jane Sykes, Lela Deans, Qingping Feng, Robert Z. Stodilka, Frank S. Prato, Gerald Wisenberg Feb 2013

Comparison Of The Myocardial Clearance Of Endothelial Progenitor Cells Injected Early Versus Late Into Reperfused Or Sustained Occlusion Myocardial Infarction, Andrea J. Mitchell, Eric Sabondjian, Kimberley J. Blackwood, Jane Sykes, Lela Deans, Qingping Feng, Robert Z. Stodilka, Frank S. Prato, Gerald Wisenberg

Paediatrics Publications

Stem cell transplantation following AMI has shown promise for the repair or reduction of the amount of myocardial injury. There is some evidence that these treatment effects appear to be directly correlated to cell residence time. This study aims to assess the effects of (a) the timing of stem cell injection following myocardial infarction, and (b) flow milieu, on cell residence times at the site of transplantation by comparing three time points (day of infarction, week 1 and week 4-5), and two models of acute myocardial infarction (sustained occlusion or reperfusion). Twenty-one dogs received 2 injections of 30 million endothelial …