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Fgf2 Maintains The Proliferation Of Neural Progenitors By Actively Suppressing The Cki P27kip1 Through Regulation Of Cks1b Transcription, Andrew J. Darr
Fgf2 Maintains The Proliferation Of Neural Progenitors By Actively Suppressing The Cki P27kip1 Through Regulation Of Cks1b Transcription, Andrew J. Darr
Open Access Dissertations
Identifying the mechanisms that regulate neural precursor cell (NPC) proliferation and differentiation is important for understanding CNS development among different vertebrates. My work has focused specifically on understanding how mitogenic factors, like basic fibroblast growth factor (FGF2), regulate the NPC cell cycle. Mitogenic factors and serum are thought to drive cell cycle and therefore proliferation mainly by activating G1-type cyclin-dependent kinases (CDKs). The general hypothesis being addressed here is that FGF2 also promotes cell cycle progression of NPCs through the degradation of the cell cycle inhibitor p27Kip1. I show that, in the presence of FGF2 in vitro, embryonic rat cortical …
Cultural-Historical Activity Perspectives On The Effects Of Participation In Teacher-Mediated, Computer-Mediated Reading Instruction, Rita M. Menendez
Cultural-Historical Activity Perspectives On The Effects Of Participation In Teacher-Mediated, Computer-Mediated Reading Instruction, Rita M. Menendez
Open Access Dissertations
The purpose of this study was to determine the effects of participation in Read 180, a teacher-mediated, computer-mediated reading instruction program, on the reading proficiency of 4th and 5th grade English Language Learners. The students who participated in the Read 180 program scored below the 25th percentile on the Florida Comprehensive Assessment Test (FCAT). Cultural-historical activity theory guided the research. Research questions for the study were answered with quantitative and qualitative methods. The questions asked were: 1. What are the effects of participation in Read 180, a teacher-mediated computer-mediated-integrated learning system that provides reading instruction, on the growth in reading …
The Influence Of Jazz Harmony And Jazz Style On Selected Bass Trombone Solo Literature, Joel Andrew Keene
The Influence Of Jazz Harmony And Jazz Style On Selected Bass Trombone Solo Literature, Joel Andrew Keene
Open Access Dissertations
The development of solo literature for the bass trombone came relatively late in the history of instruments. Though the development of solo literature for this instrument and the birth and development of jazz occurring at the same time in history may be coincidental, the influence of one on the other is undeniable. Because of the large percentage of solo bass trombone literature that is influenced by jazz due to this coincidence, it is necessary that even a classically trained bass trombonist include jazz as a part of the study curriculum. In order to exemplify the influences of jazz harmony and …
Materials For Sustainable Constructions, Rosella Mafalda Ferraro
Materials For Sustainable Constructions, Rosella Mafalda Ferraro
Open Access Dissertations
White cement has currently received increasing attention due to potential for use in sustainable concrete structures. Based on the U.S. Green Building Council certification practice, the LEED Green Building Rating System for New Construction and Major Renovation (LEED-NC) considers that the reflective quality of white surfaces may help to improve lighting efficiency and reduce temperature fluctuations, resulting in lower heating and cooling with reduction of related energy costs. In addition to the environmental impact, white concrete represents a valuable tool for the aesthetic acceptability of a structure, and can also offer important practical benefits in terms of safety (i.e., light …
Modernizing Nationalism: Masculinity And The Performance Of Anglophone Caribbean Identities, Nadia Indra Johnson
Modernizing Nationalism: Masculinity And The Performance Of Anglophone Caribbean Identities, Nadia Indra Johnson
Open Access Dissertations
This study examines Anglophone Caribbean national identities to interrogate multiple and varied economies that manage citizens in the interest of economic and social production and/or the policing of national identities. It is particularly concerned with the gendered character of these economies. The formation and preservation of these national identities rely heavily on gender and sexual difference as Anglophone Caribbean national identities are inextricably linked to expressions of Afro-Caribbean masculinity. Thus I analyze novels and cultural representations of Afro-Caribbean masculinity in cricket, calypso and chutney-soca music in Trinidad's carnival. I also examine Afro-Caribbean religions, Revivalism and Rastafarianism, as well as Afro-Caribbean …
Behavior Of Full-Scale Reinforced Concrete Members With External Confinement Or Internal Composite Reinforcement Under Pure Axial Load, Antonio De Luca
Behavior Of Full-Scale Reinforced Concrete Members With External Confinement Or Internal Composite Reinforcement Under Pure Axial Load, Antonio De Luca
Open Access Dissertations
The need to satisfy aerospace industry's demand not met by traditional materials motivated researchers and scientists to look for new solutions. The answer was found in developing new material systems by combining together two or more constituents. Composites, also known as fiber reinforced polymers (FRP) consisting of a reinforcing phase (fibers) embedded into a matrix (polymer), offered several advantages with respect to conventional materials. High specific modulus and strength together with other beneficial properties, corrosion resistance and transparency to electrical and magnetic fields above all, made FRP also suitable for use as construction materials in structural engineering. In the early …
Emotion Recognition Using Glottal And Prosodic Features, Alexander Iliev Iliev
Emotion Recognition Using Glottal And Prosodic Features, Alexander Iliev Iliev
Open Access Dissertations
Emotion conveys the psychological state of a person. It is expressed by a variety of physiological changes, such as changes in blood pressure, heart beat rate, degree of sweating, and can be manifested in shaking, changes in skin coloration, facial expression, and the acoustics of speech. This research focuses on the recognition of emotion conveyed in speech. There were three main objectives of this study. One was to examine the role played by the glottal source signal in the expression of emotional speech. The second was to investigate whether it can provide improved robustness in real-world situations and in noisy …
A Comparison Of Adjacent Categories And Cumulative Dsf Effect Estimators, Karina A. Gattamorta
A Comparison Of Adjacent Categories And Cumulative Dsf Effect Estimators, Karina A. Gattamorta
Open Access Dissertations
The study of measurement invariance in polytomous items that targets individual score levels is known as differential step functioning (DSF; Penfield, 2007, 2008). DSF methods provide specific information describing the manifestation of the invariance effect within particular score levels and therefore serve a diagnostic role in identifying the individual score levels involved in the item's invariance effect. The analysis of DSF requires the creation of a set of dichotomizations of the item response variable. There are two primary approaches for creating the set of dichotomizations to conduct a DSF analysis. The first approach, known as the adjacent categories approach, is …
Manipulating Embryonic Neural Precursor Cells For Therapeutic Transplantation Into A Rat Model Of Neuropathic Pain, Orion Furmanski
Manipulating Embryonic Neural Precursor Cells For Therapeutic Transplantation Into A Rat Model Of Neuropathic Pain, Orion Furmanski
Open Access Dissertations
Persons with spinal cord injury (SCI) suffer life-long consequences including paralysis, loss of involuntary bodily functions, and chronic pain. A subset of SCI patients develop neuropathic pain (NP), a chronic condition resulting from damage to the spinal cord. Hyperexcitability of spinal cord sensory neurons near damaged tissue is believed to underlie SCI-related NP. Although many therapies have been employed clinically to combat SCI-NP, few give satisfactory long-term relief. Transplantation of cells that release GABA, a molecule that inhibits neuronal activity, is being explored as an alternative to current SCI-NP therapies. My experiments made progress toward preclinical modeling of GABA cell …
A Multi-Model Approach To Predicting Pathogen Indicator Bacteria Loading In Tmdl Analyses, Donna-May G. Sakura-Lemessy
A Multi-Model Approach To Predicting Pathogen Indicator Bacteria Loading In Tmdl Analyses, Donna-May G. Sakura-Lemessy
Open Access Dissertations
This dissertation utilizes data from four sub-watersheds in the Little River Experimental Watershed, GA to develop models to improve forecast predictions related to the management of surface-water pollution due to non-point source runoff. Non-point source pollution is the primary cause of US surface-water quality impairment and a main transport mechanism for pathogens and other pollutants into receiving surface water bodies (US EPA 2008). In response to pollution reduction and watershed remediation mandates under the Federal Clean Water Act (1972)-particularly the Total Maximum Daily Load (TMDL) program-the role of water quality modeling in effectively rehabilitating impaired waters has taken on greater …
Marc-Antoine Charpentier's Messe Pour Monsieur Mauroy, Korre D. Foster
Marc-Antoine Charpentier's Messe Pour Monsieur Mauroy, Korre D. Foster
Open Access Dissertations
Marc-Antoine Charpentier's setting of the Messe pour Monsieur Mauroy is the only composition in his oeuvre which was dedicated to a particular person. Each of Charpentier's twelve mass settings is unique; this mass setting is his longest at over 1,500 measures. Charpentier masses are diverse: one composition for women's voices, a mass for instruments only, a Christmas mass, as well as settings of the Requiem text. This document traces the history of the missa concertata up until the time of Charpentier. It examines the intricacies of Charpentier's compositional process: form, melody, harmony, and self-borrowing. This paper also analyzes recent findings …
On The Response To Tropical Cyclones In Mesoscale Oceanic Eddies, Benjamin Jaimes
On The Response To Tropical Cyclones In Mesoscale Oceanic Eddies, Benjamin Jaimes
Open Access Dissertations
Tropical cyclones (TCs) often change intensity as they move over mesoscale oceanic features, as a function of the oceanic mixed layer (OML) thermal response (cooling) to the storm's wind stress. For example, observational evidence indicates that TCs in the Gulf of Mexico rapidly weaken over cyclonic cold core eddies (CCEs) where the cooling response is enhanced, and they rapidly intensify over anticyclonic warm features such as the Loop Current (LC) and Warm Core Eddies (WCEs) where OML cooling is reduced. Understanding this contrasting thermal response has important implications for oceanic feedback to TCs' intensity in forecasting models. Based on numerical …
Correlation Between High Resolution Sequence Stratigraphy And Mechanical Stratigraphy For Enhanced Fracture Characteristic Prediction, Laiyyan M. Al Kharusi
Correlation Between High Resolution Sequence Stratigraphy And Mechanical Stratigraphy For Enhanced Fracture Characteristic Prediction, Laiyyan M. Al Kharusi
Open Access Dissertations
Sequence stratigraphy relates changes in vertical and lateral facies distribution to relative changes in sea level. These relative changes in carbonates effect early diagenesis, types of pores, cementation and dissolution patterns. As a result, in carbonates, relative changes in sea level significantly impact the lithology, porosity, diagenesis, bed and bounding surfaces which are all factors that control fracture patterns. This study explores these relationships by integrating stratigraphy with fracture analysis and petrophysical properties. A special focus is given to the relationship between mechanical boundaries and sequence stratigraphic boundaries in three different settings: 1) Mississippian strata in Sheep Mountain Anticline, Wyoming, …
The Influence Of Music On Depression, Affect, And Benefit Finding Among Women At The Completion Of Treatment For Breast Cancer, Julie J. Stordahl
The Influence Of Music On Depression, Affect, And Benefit Finding Among Women At The Completion Of Treatment For Breast Cancer, Julie J. Stordahl
Open Access Dissertations
Women at the completion of treatment for breast cancer experience relief along with continued physical and psychological distress. This study explored the effectiveness of two forms of a Relaxation Intervention in providing psychosocial support to women at the completion of treatment for breast cancer. The two conditions included (1) Music-Assisted Relaxation (MAR), in which contemporary, sedative music was paired with standard, spoken relaxation directives, and (2) Relaxation Alone (RA), in which only spoken relaxation directives were used. Individual sessions were held once each week for four weeks. This study included a mixed method design. Quantitative measures included The Center for …
April (Tnfsf13) In Th1, Th2 And Th17 Responses, Yanping Xiao
April (Tnfsf13) In Th1, Th2 And Th17 Responses, Yanping Xiao
Open Access Dissertations
The T cell function of a proliferation inducing ligand (APRIL or TNFSF13) remains unclear. By comparing APRIL-/- mice with wild type (WT) mice, we have investigated the roles of APRIL in Th1, Th2 and Th17 responses. With regard to APRIL in Th1 responses, cultured APRIL-/- CD4+ T cells showed increased IFN-gamma production under non-polarizing, but not under Th1 polarizing, conditions. No difference in antigen-specific IgG2a levels existed between APRIL-/- and WT mice immunized with ovalbumin (OVA) and complete Freund's adjuvant (CFA) which induces Th1 polarization. Our data indicate that APRIL represses Th1 responses only under non-polarizing conditions. As for APRIL …
A Conductor's Guide To Two Cantatas By Philipp Heinrich Erlebach: Ich Will Wasser Giessen And Christus Ist Mein Leben, Tobin Christopher Sparfeld
A Conductor's Guide To Two Cantatas By Philipp Heinrich Erlebach: Ich Will Wasser Giessen And Christus Ist Mein Leben, Tobin Christopher Sparfeld
Open Access Dissertations
Philipp Heinrich Erlebach (1657-1714) was a court composer and music director in the central German town of Schwarzburg-Rudolstadt. During his day, Erlebach mastered nearly every genre of his era and turned the court of Rudolstadt into a sophisticated musical center. Unfortunately, a fire which consumed the Rudolstadt court in 1735 destroyed many of his sacred and secular manuscripts. Erlebach had a marked influence on the development of the sacred cantata. He was one of the first composers to write a cycle of texts by Erdmann Neumeister, the earliest cycle of Neumeister cantatas that survives. This study provides background and analysis …
The Effects Of A Chinese Music Curriculum On Cultural Attitudes, Tonal Discrimination, Singing Accuracy, And Acquisition Of Chinese Lyrics For Third-, Fourth-, And Fifth-Grade Students., Ming Tu
Open Access Dissertations
The purpose of the study was to investigate the effect of 10 minutes of daily exposure for 10 weeks to a Chinese Music Curriculum and its effect on generating positive cultural attitudes towards the Chinese people, improving tonal discrimination skills, singing accuracy of tonal patterns, and accuracy of singing Chinese lyrics for third-, fourth-, and fifth-grade students, compared to a comparison group not receiving the Chinese Music Curriculum. In an elementary school in Miami-Dade County, Florida, 6 third-, fourth-, and fifth-grade classes were chosen and randomly assigned to either an intervention or a comparison group. A Chinese Music Curriculum was …
Design And Evaluation Of Three Alternative Keyboard Layouts For A Five-Key Text Entry Technique, Barbara Millet
Design And Evaluation Of Three Alternative Keyboard Layouts For A Five-Key Text Entry Technique, Barbara Millet
Open Access Dissertations
Despite the increase in popularity of handheld devices, text entry on such devices is becoming more difficult due to reduced form factors that limit display size, input modes, and interaction techniques. In an effort to circumvent these issues, research has found that five-key methods are effective for text entry on devices such as in-car navigation systems, television and gaming controllers, wrist watches, and other small devices. Five-key text entry methods use four directional keys to move a selector over an on-screen keyboard and an Enter key for selection. Although other researchers have described five-key character layouts using alphabetical order and …
Biology Of Amacrine Cells And Retinal Ganglion Cells In The Developing Retina, Noelia J. Kunzevitzky
Biology Of Amacrine Cells And Retinal Ganglion Cells In The Developing Retina, Noelia J. Kunzevitzky
Open Access Dissertations
How do neighboring neurons differ? How are they similar? How do they relate to each other? Retinal ganglion cells (RGCs) and amacrine cells are born during the same developmental window, from the same population of progenitor cells, and some amacrine cells even migrate to the same retinal layer where RGCs reside, the ganglion cell layer. Amacrine cells are presynaptic to RGCs, whose axons subsequently project through the optic nerve and carry visual information to the brain. Although the cell biology of RGCs has been studied in some detail, relatively little is known about the cell and molecular biology of amacrine …
Parents' Impressions Of Their Child's Minor Surgical Procedure With Nitrous Oxide, Tina Shapiro-Stoler
Parents' Impressions Of Their Child's Minor Surgical Procedure With Nitrous Oxide, Tina Shapiro-Stoler
Open Access Dissertations
Invasive procedures are often painful and distressing for children and disturbing for their parents. The purpose of this study was to develop a substantive theory of parental perceptions of their school-aged child's responses to an outpatient minor surgical procedure with nitrous oxide. The sample included 22 parents of 21 children who underwent a nitrous procedure. Participants were recruited from the pediatric surgery department at a children's hospital. Semi-structured, audio-recorded interviews were conducted with each participant. Grounded theory method was used to simultaneously collect and analyze the data using the constant comparative method. The findings of the study revealed parental impressions …
Transcription And Analysis Of Selected Trombone Solos From J. J. Johnson's 1964 Recording Proof Positive, Rodney Allen Lancaster
Transcription And Analysis Of Selected Trombone Solos From J. J. Johnson's 1964 Recording Proof Positive, Rodney Allen Lancaster
Open Access Dissertations
The purposes of the essay are to transcribe and analyze selected solos from the 1964 J. J. Johnson recording, Proof Positive as well as to increase the amount of analytical literature on J. J. Johnson presently obtainable for study by jazz trombonists. J. J. Johnson will further be affirmed as a jazz musician worthy of doctoral level study. Selected solos from the 1964 J. J. Johnson recording Proof Positive will be transcribed and analyzed in depth using a method of analysis incorporating improvisational devices identified by the author. A brief biography of J. J. Johnson is presented along with a …
Comparison Of Targeted Lower Extremity Strengthening And Usual Care Progressive Ambulation In Subjects Post-Liver Transplant: A Randomized Controlled Trial, David Walter Mandel
Comparison Of Targeted Lower Extremity Strengthening And Usual Care Progressive Ambulation In Subjects Post-Liver Transplant: A Randomized Controlled Trial, David Walter Mandel
Open Access Dissertations
Individuals with chronic liver disease experience progressive muscle wasting, weakness, fatigue, and decreased quality of life. Liver transplantation is the only treatment for end-stage liver disease with cirrhosis; however, muscle wasting, strength impairments, activity limitations, and health related quality of life do not return to the level of healthy adults. Currently there is no plan of care for rehabilitation of individuals post-liver transplantation. These individuals are only instructed to gradually increase walking and activity. Walking may increase lower extremity muscle strength; however, walking at a self-selected pace is less effective than resistance exercise. The purpose of this dissertation was to …
The Blog Election: An Analysis Of The Source Interaction Between Traditional News Media And Blogs In Their Coverage Of The 2006 Congressional Midterm Elections, Marcus Messner
Open Access Dissertations
Political blogs have emerged as a new journalistic format that has gained influence on the political discourse in the United States. Previous research has shown that this influence stems mainly from attention given to blogs by traditional news media. Based on the concepts of intermedia agenda setting and agenda building, this study explored the source interaction between 10 elite traditional news media and 10 political filter blogs during the 2006 Congressional Midterm Elections. An analysis of 2587 sources used in the election context found that traditional news media frequently cited blogs in their election coverage, but that the source attributions …
Chemistry Of Iron And Other Trace Elements In Trade Wind Aerosols And Precipitation, John Michael Trapp
Chemistry Of Iron And Other Trace Elements In Trade Wind Aerosols And Precipitation, John Michael Trapp
Open Access Dissertations
The atmospheric transport of various substances from the continents to the oceans plays an important role in biogeochemical processes. Trace metals, iron in particular is of great interest as its availability regulates the growth of phytoplankton over large areas of the ocean. This dissertation focuses on examining and characterizing the factors that affect the solubility of trace metals in Miami and Barbados aerosols and precipitation, in particular species that could play a role in surface seawater biogeochemistry (Fe and trace metals such as Al, V, Cr, Mn, Cu, Co, Ni, Zn, As, Tl, Ba, Cd, Pb, Th, Ti, Zr, and …
Heitor Villa-Lobos's Mômoprecóce Fantasy For Piano And Orchestra (1919-1929): An Historical, Stylistic, And Interpretative Study, Simone Azevedo Leitão
Heitor Villa-Lobos's Mômoprecóce Fantasy For Piano And Orchestra (1919-1929): An Historical, Stylistic, And Interpretative Study, Simone Azevedo Leitão
Open Access Dissertations
The life and works of the Brazilian composer Heitor Villa-Lobos (1887-1959) have been well documented. However, a comprehensive study concerning any of his nine works for piano and orchestra has not been undertaken. Among this prolific output, the Mômoprecóce, fantasie pour piano et orchestra, stands as a faithful representation of the composer's skillful orchestration, descriptive piano writing through the observation of a childhood universe, and his multi-faceted approach to nationalism. The fantasy is a through-composed arrangement of a previous solo piano suite by Villa-Lobos entitled, Carnaval das crianças brasileiras (Brazilian Children's Carnival, 1919). This research aims to investigate the historic, …
Associations Between Asd Symptomatology And Cognitive Functioning In Siblings, Susan Ivette Acosta
Associations Between Asd Symptomatology And Cognitive Functioning In Siblings, Susan Ivette Acosta
Open Access Dissertations
Siblings of children with autism (ASD-sibs) often exhibit deficits in social reciprocity and cognitive deficits similar to those of their affected siblings. The purpose of this study was to examine the associations between degree of autistic symptomatology and degree of cognitive functioning in sibling pairs seen as part of a longitudinal ASD-focused sibling study. Both cognitive functioning and autistic symptomatology were assessed using continuous measures in sibling pairs. Three sets of bivariate correlations were conducted to examine the relationships between autistic symptomatology and cognitive ability. One ANCOVA and 6 ANOVAS were also conducted to identify possible group differences between younger …
The Effects Of Yoga On Symptoms Associated With Conduct Disorder With Callous Unemotional Traits As A Moderator, Kym M. Mccabe
The Effects Of Yoga On Symptoms Associated With Conduct Disorder With Callous Unemotional Traits As A Moderator, Kym M. Mccabe
Open Access Dissertations
The purpose of this research was to investigate the additive therapeutic effects of a yoga intervention on the anxiety, depression and behavioral problems of conduct-disordered male adolescents in residential treatment. In addition, the moderating effects of callous-unemotional (CU) traits on outcome measures were assessed. The program consisted of a four-week intervention program in which participants were randomly assigned to either the yoga group (n=25), in which they practiced yoga with an instructor, or the control group (n=19), in which they met for a supervised study hall. The study included pre-testing on symptoms of anxiety, depression and CU traits, and post-testing …
Assessing The Early Life Stage Processes That Regulate Recruitment In The Brooding Coral, Porites Astreoides, Wade T. Cooper
Assessing The Early Life Stage Processes That Regulate Recruitment In The Brooding Coral, Porites Astreoides, Wade T. Cooper
Open Access Dissertations
Population replenishment through recruitment is an essential process for the long term viability of corals and their associated communities, particularly under increasing stresses that threaten their vitality. Although many researchers have identified specific factors that influence individual processes in the early life cycle of corals, few studies to date have attempted to determine the cumulative success of a cohort's progression through these stages in natural reef settings. Specifically, there is a paucity of knowledge regarding appropriate and realistic techniques to forecast the success of recruitment in natural settings, while taking into account both the individual and environmental factors that regulate …
Modeling Molecular Transport And Binding Interactions In Intervertebral Disc, Francesco Travascio
Modeling Molecular Transport And Binding Interactions In Intervertebral Disc, Francesco Travascio
Open Access Dissertations
Low back pain represents a significant concern in the United States, with 70% of individuals experiencing symptoms at some point in their lifetime. Although the specific cause of low back pain remains unclear, symptoms have been strongly associated with degeneration of the intervertebral disc. Insufficient nutritional supply to the disc is believed to be a major mechanism for tissue degeneration. Understanding nutrients' transport in intervertebral disc is crucial to elucidate the mechanisms of disc degeneration, and to develop strategies for tissue repair (in vivo), and tissue engineering (in vitro). Transport in intervertebral disc is complex and involves a series of …
Franco Margola's Chamber Works With Guitar: A Guide And Annotated Catalog, Federico Bonacossa
Franco Margola's Chamber Works With Guitar: A Guide And Annotated Catalog, Federico Bonacossa
Open Access Dissertations
This essay came about as a result of the desire to study and collect the guitar music of Franco Margola. Franco Margola composed over 450 works for guitar, most of which are unpublished and virtually all of which are unknown to most guitarists. This essay focuses on Margola's chamber works with guitar, which include some of his best compositions. The study contains historical background information, an ample biography, as well as an overview of the currently published works for solo guitar. The main portion of the essay consists of an outline and an annotated catalog of all of Margola's chamber …