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Mechanisms Behind The Luteoprotective Effects Of Fish Meal Supplementation In Bovine: Cytokine Sensitivity And Luteal Blood Flow, Anika Shelrud
Mechanisms Behind The Luteoprotective Effects Of Fish Meal Supplementation In Bovine: Cytokine Sensitivity And Luteal Blood Flow, Anika Shelrud
Master's Theses
Early pregnancy loss continues to be problematic in the cattle industry. A large proportion of the pregnancy loss occurs during the maternal recognition of pregnancy (MRP) phase of gestation. During the MRP, a developing conceptus must secrete sufficient interferon tau to inhibit release of the uterine- derived and luteolytic mediator, prostaglandin F2 alpha (PGF2��). If successful, the progesterone- secreting corpus luteum (CL) will be maintained, which is necessary for establishment and maintenance of pregnancy. Pregnancy loss at the point of MRP may be due to a slow developing conceptus that does not effectively block PGF2��. Therefore, reducing the influence of …
Conservation Genomics: Utilizing Genetic And Transcriptomic Sequencing For Effective Conservation Management Of Astragalus Osterhoutii, Christine Mowad
Conservation Genomics: Utilizing Genetic And Transcriptomic Sequencing For Effective Conservation Management Of Astragalus Osterhoutii, Christine Mowad
Master's Theses
Astragalus osterhoutii M.E. Jones (Fabaceae) is a federally listed, rare, endemic species restricted to seleniferous soils in Grand County, CO (Anderson, 1989). This research utilized both RADseq and RNAseq to generate neutral and adaptive genomic datasets. Neutral data analysis aimed to determine i) the genetic diversity of A. osterhoutii and each of its populations level, ii) how genetic structure is partitioned across the species range, and iii) the closest relative to A. osterhoutii. Analysis of adaptive, RNAseq data aimed to identify i) differentially expressed genes, ii) if patterns of expression are similar to neutral data, and iii) differences in Se …
Immunological Effects Of Berberine And Physical Activity In A Murine Breast Cancer Model, Janae Mudge
Immunological Effects Of Berberine And Physical Activity In A Murine Breast Cancer Model, Janae Mudge
Master's Theses
Berberine (BBR) is a plant-derived alkaloid popularly used in a complementary context to treat splenomegaly and chronic disease states such as rheumatoid arthritis, diabetes, and cancer. Recent research has examined BBR as a regulator of lipid and glucose metabolism in association with the AMPK pathway; but little is known concerning its immunological impacts. It is also known that exercise is a potent AMPK activator exhibiting immunological benefits, but nothing is known about the combination of these complementary approaches for treating breast cancer. The purpose of this study is to determine if oral consumption of BBR when paired with physical activity …
Understanding Species Boundaries Between Penstemon Acaulis And Penstemon Yampaensis: Implications For Conservation And Management, Juliet Simpson
Understanding Species Boundaries Between Penstemon Acaulis And Penstemon Yampaensis: Implications For Conservation And Management, Juliet Simpson
Master's Theses
Effective conservation management relies upon accurate taxonomic information and an understanding of the genetic health and population structure for each species. Penstemon acaulis and P. yampaensis are endemic species to Colorado, Utah, and Wyoming, and have been considered for listing under the Endangered Species Act (ESA). There is little biological data published about either and there remains taxonomic uncertainty surrounding the two. Phylogenetic analyses showed P. acaulis and P. yampaensis to be distinct, monophyletic lineages and morphological data further supported taxonomic recognition of both species, however these results did not support the previous species boundaries. Eastern populations of P. acaulis …
Topo-Climatic Effects Of Fuel Loading In Ponderosa Pine (Pinus Ponderosa) Forests Of The Colorado Rocky Mountains, Justin Yow
Master's Theses
A key restoration focus is the mitigation and prevention of intense wildfires. This is done using a regularly prescribed fire regime and forest thinning practices to reduce surface fuel loads. Prediction of fuel loads at the forest floor is pivotal when assessing the hazard level a forest fire may present. Scientists already have much data correlating fuel characteristics to fire effects and behavior. However, links between montane climate variability and relative effects on fuel load characteristics have not been extensively explored in the Front Range and southwestern Colorado. This study system was uniquely located along a North-South monsoonal gradient and …
Genetic Analysis Of The Rare, Colorado Endemic Rocky Mountain Monkeyflower, Mimulus Gemmiparus, Branson Wetzstein
Genetic Analysis Of The Rare, Colorado Endemic Rocky Mountain Monkeyflower, Mimulus Gemmiparus, Branson Wetzstein
Master's Theses
Mimulus gemmiparus is a rare, Colorado endemic plant which possesses a limited range, strict habitat requirement, and unique life history. Most peculiarly, Mimulus gemmiparus seemingly relies entirely on clonal spread using vegetative propagules known as brood bulbils to persist year to year. This inconspicuous annual is only found within a narrow range of Colorado’s Rocky Mountains, possessing a total known range of about 2500 km2. There are currently 11 known natural populations of Mimulus gemmiparus spread across three general regions: North (Larimer, Boulder, and Grand Counties), Central (Clear Creek and Jefferson Counties), and South (Jefferson County). Lack of sexual reproduction, …
The Role Of Aryl Hydrocarbon Receptor Activation On Immunoglobulin A-Secreting B Cell Gut Homing, Linda Ortiz
The Role Of Aryl Hydrocarbon Receptor Activation On Immunoglobulin A-Secreting B Cell Gut Homing, Linda Ortiz
Master's Theses
Within the United States, foodborne diseases are estimated to result in more than 100,000 hospitalizations each year with 3,000 fatalities. Acute gastroenteritis impacts more than 1.5 million children each year in the United States. Worldwide, childhood morbidity and mortality are largely attributed to infectious diarrheal diseases. To combat infection at mucosal surfaces, immunoglobulin (Ig) A is produced by antibody-secreting B cells to inhibit and neutralize pathogens and their toxins. B cells are influenced by various extrinsic signals through activation of the aryl hydrocarbon receptor (AhR). The AhR is a ligand-activated transcription factor that links diet and environmental factors to intestinal …