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The Examination Of The Function Of The Cofactor Schnurri In The Cyst Stem Cells Of The Drosophila Melanogaster Testis Niche, Jade Koretko
The Examination Of The Function Of The Cofactor Schnurri In The Cyst Stem Cells Of The Drosophila Melanogaster Testis Niche, Jade Koretko
Master's Theses
The study of adult stem cells in modern day research provides pertinent information about the development of organisms, how they grow, and how tissue is maintained. Drosophila melanogaster provide an ideal model for in vivo stem cell research, with one of the best-characterized niches in the testis. The testis stem cell niche consists of a hub that provides signals to the local stem cells, germline stem cells (GSCs), and cyst stem cells (CySCs). The CySCs produce cyst cell lineage that will provide support for the GSC daughter cells, which differentiate into sperm. Previously, Matunis, et al. determined the function of …
Characterizing The Role Of Tumor Suppressors Merlin And Expanded In The Stem Cell Niche Of Drosophila Testes, Bryan Johnson
Characterizing The Role Of Tumor Suppressors Merlin And Expanded In The Stem Cell Niche Of Drosophila Testes, Bryan Johnson
Master's Theses
The ability of adult organisms to maintain tissue homeostasis and repair tissue in response to injury is mediated by small groups of partially differentiated cells called adult stem cells that support the tissue they reside in. Adult stem cell maintenance is highly regulated by signals from the surrounding microenvironment referred to as the stem cell niche. A better understanding of this process will have important implications for the fields of both regenerative medicine and cancer biology. Due to the complexity of most niche environments in mammals, we turned to the less complex model organism Drosophila and the well-characterized niche in …
A Description Of Lichen Community Structure And The Impacts Of Spruce Beetle Disturbance In Northwestern Colorado, Anna Freundlich
A Description Of Lichen Community Structure And The Impacts Of Spruce Beetle Disturbance In Northwestern Colorado, Anna Freundlich
Master's Theses
Spruce beetle disturbance has affected millions of acres of forest throughout North America and Europe, but thus far little research has investigated how this disturbance influences lichen communities. To address this problem, we studied lichen communities and habitat characteristics within 44 plots across a chronosequence of spruce beetle damage spanning 1996–2017 in northwestern Colorado. We found 82 species of lichens, few habitat differences among spruce beetle disturbance classes, and only the most recently affected plots (2012–2017) had significantly different lichen community structure relative to remaining areas. Two primary gradients explained the majority of variation of lichen community structure within our …
Characterizing The Susceptibility And Type I Interferon Response Of Primary Mammalian Cells During Zika Virus Infection, Douglas Petty
Characterizing The Susceptibility And Type I Interferon Response Of Primary Mammalian Cells During Zika Virus Infection, Douglas Petty
Master's Theses
Zika virus (ZIKV), a member of the genus Flavivirus, has become a major public health concern since 2007. During the most recent 2015 outbreak, ZIKV rapidly spread from South America to over 84 countries and territories across the world in two years. ZIKV has also been associated with previously uncharacterized neurological manifestations during the 2013 and 2015 outbreaks. The novel manifestations include Guillain-Barré Syndrome (GBS) in adults and Congenital Zika Syndrome (CZS) in newborns. GBS is a progressive paralysis caused by damage to the peripheral nervous system; while CZS is an all-encompassing term for the severe neurological and developmental complications …
Sagebrush Seeds Of Success: A Genetic Analysis Of Bureau Of Land Management Seeds Of Success Seeds And Of Eriogonum Umbellatum, Emily Katherine Schumacher
Sagebrush Seeds Of Success: A Genetic Analysis Of Bureau Of Land Management Seeds Of Success Seeds And Of Eriogonum Umbellatum, Emily Katherine Schumacher
Master's Theses
Due to the increasing frequency of anthropogenic disturbances, greater effort needs to be put into identifying appropriate seed material for large scale restoration projects. The Bureau of Land Management created the Seeds of Success (SOS) project to increase stocks of native seeds for restoration projects following worsening disturbances. However, there is little known about the genetic composition of these seeds, so it is unclear if these seed accessions will be able to establish healthy and persistent native plant communities. This thesis identified that in 20 accessions of SOS seeds, inbreeding was low to moderate in 17 accessions, allelic richness was …
Intraspecific Functional Trait Diversity In Big Sagebrush-Associated Species And Implications For Ecological Restoration, Gwen Schneider
Intraspecific Functional Trait Diversity In Big Sagebrush-Associated Species And Implications For Ecological Restoration, Gwen Schneider
Master's Theses
Big sagebrush ecosystems are widespread throughout the western United States and provide essential ecosystem services, including water and nutrient cycling, energy capture, and habitat for sagebrush obligate taxa. Notably, sagebrush ecosystems provide habitat for the greater sage grouse (Centrocercus urophasianus), which is a nearly threatened species of high concern. Sagebrush habitat has experienced a 45% reduction in range, and a large portion of intact habitat is at risk of loss from severe fire,cheatgrass (Bromus tectorum) invasion, encroachment of pinyon-juniper woodlands, fragmentation due to human development, and changes associated with anthropogenic climate change. Thus, it is of high conservation significance to …
The Effects Of Fish Meal Supplementation On Gene Expression In The Bovine Corpus Luteum Following Low Dose Administration Of Prostaglandin F2a, Jessica Claire Cedillo
The Effects Of Fish Meal Supplementation On Gene Expression In The Bovine Corpus Luteum Following Low Dose Administration Of Prostaglandin F2a, Jessica Claire Cedillo
Master's Theses
The corpus luteum is a transient endocrine gland that develops from the remnants of the ovulatory follicle and secretes the steroid hormone progesterone. Progesterone is essential in the establishment and maintenance of pregnancy in all mammalian species. In the non-pregnant bovine, uterine prostaglandin F2α is secreted in a series of pulses between days 15 and 17 after ovulation, allowing the corpus luteum to undergo functional and structural regression and an opportunity for mating. During early pregnancy, trophoblastic cells of the developing embryonic placenta secrete interferon-tau, which attenuates uterine prostaglandin F2α secretion allowing for maintenance of the corpus luteum during the …