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Development And Validation Of A Human Hip Joint Finite Element Model For Tissue Stress And Strain Predictions During Gait, Jeffrey D. Pyle Dec 2013

Development And Validation Of A Human Hip Joint Finite Element Model For Tissue Stress And Strain Predictions During Gait, Jeffrey D. Pyle

Master's Theses

Articular cartilage degeneration, called osteoarthritis, in the hip joint is a serious condition that affects millions of individuals yearly, with limited clinical solutions available to prevent or slow progression of damage. Additionally, the effects of high-risk factors (e.g. obesity, soft and hard tissue injuries, abnormal joint alignment, amputations) on the progression of osteoarthritis are not fully understood. Therefore, the objective of this thesis is to generate a finite element model for predicting osteochondral tissue stress and strain in the human hip joint during gait, with a future goal of using this model in clinically relevant studies aimed at prevention, treatment, …


Protein Turnover In Trained Male Endurance Runners Following Exercise, Jeffrey Del Favero Sep 2013

Protein Turnover In Trained Male Endurance Runners Following Exercise, Jeffrey Del Favero

Master's Theses

No abstract provided.


Genetic Determinants Of Habitual Physical Activity And Overweight And Obesity, Harold Lee Jul 2013

Genetic Determinants Of Habitual Physical Activity And Overweight And Obesity, Harold Lee

Master's Theses

We tested 6 single nucleotide polymorphisms (SNPs) associated with obesity from genome wide association studies for their association with physical activity (PA). Healthy European-American women (n=265) and men (n=230) (23.5±0.3yr, 24.6±0.2kg•m-2) were genotyped for MC4R (rs17782313), FTO (rs9939609), TMEM18 (rs6548238), NEGR1 (rs2815752), SH2B1 (rs7498665), and KCTD15 (rs11084753), and completed the Paffenbarger PA Questionnaire. We examined gene interactions by summing the number of obesity effect alleles. RESULTS: Normal weight subjects with MC4R T expended 1981.2±741.7kcal∙wk-1 less than non-carriers in total PA (p=0.008), 1825.9±650.2 kcal∙wk-1 less in sports/recreation (p=0.027), and 1231.3±552.7 kcal∙wk-1 less …


A Meta-Analysis Of Candidate Gene Association Studies On The Blood Pressure Response To Aerobic Exercise, Michael L. Bruneau Jr May 2013

A Meta-Analysis Of Candidate Gene Association Studies On The Blood Pressure Response To Aerobic Exercise, Michael L. Bruneau Jr

Master's Theses

ABSTRACT

Purpose: Aerobic exercise (AE) lowers blood pressure (BP) 5-7 mmHg among those with hypertension, but there is considerable variability in the BP response to AE. Genetic predispositions account for 40-65% of this variability; however, identifying genetic variants that associate with the BP response to AE is a challenge. We performed a meta-analysis to integrate the small number of studies that examined the influence of candidate genes on the BP response to AE. Methods: Studies retrieved included an acute or chronic AE intervention; BP before and after AE by genotype; and candidate gene polymorphisms. Effect sizes were the standardized mean …


The Relation Between The Blood Pressure Response To Exercise During Training And Detraining Periods, Emily A. Moker May 2013

The Relation Between The Blood Pressure Response To Exercise During Training And Detraining Periods, Emily A. Moker

Master's Theses

Exercise training lowers blood pressure (BP) 5-7 mmHg, but the relation between the BP response to exercise training and detraining is unclear. PURPOSE: To examine the BP response after 6m of training followed by 2wk of detraining among a subsample from the Studies of a Targeted Risk Reduction Intervention through Defined Exercise study. METHODS: Subjects were 38 men and 37 women 50.2±10.6y with a body mass index of 30.5±3.2kg·m-2 and resting BP of 120.0±13.7/79.1±9.2mmHg. Subjects completed 1of 3 types of exercise training: aerobic (AE) vigorous intensity (n=34); resistance training (RT) (n=28); or AE vigorous and RT (n=13). Simple …


An Investigation Of Preferred Versus Imposed Exercise, Personality Traits, And Motivation On An Exercise Dependent College Aged Sample 2013, Chelsea M. Norton May 2013

An Investigation Of Preferred Versus Imposed Exercise, Personality Traits, And Motivation On An Exercise Dependent College Aged Sample 2013, Chelsea M. Norton

Master's Theses

The purpose of this study was to: (a) investigate personality traits and motivation among an exercise dependent sample by using and examining theoretically based assessment tools and (b) measure feeling states under different types of physical activity among those who were considered to be exercise dependent. Four hundred twenty-three college students (54.4% male, 45.6% female) who met the inclusion criteria completed the Exercise Dependence Scale-Revised (EDS-R; Symons Downs, Hausenblas, & Nigg, 2004), Exercise Addiction Inventory (EAI; Terry, Szabó, & Griffiths, 2004), Exercise Identity Scale (EIS; Anderson & Cychosz, 1994), Behavioral Regulations in Exercise Questionnaire-2 (BREQ-2; Markland & Tobin, 2004), and …