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Retinoic Acid Receptor Isoform-Specific Control Of Mouse Salivary Gland Development And Regeneration, Kara Desantis
Retinoic Acid Receptor Isoform-Specific Control Of Mouse Salivary Gland Development And Regeneration, Kara Desantis
Legacy Theses & Dissertations (2009 - 2024)
Controlled expansion and differentiation of progenitor cell populations is essential for organogenesis followed by continued maintenance of the population into and through adulthood. As the K5+ basal cell population is regulated by retinoic acid signaling, we interrogated the contribution of specific RAR isoforms to the regulation of these cells during submandibular salivary gland (SMG) organogenesis and regeneration. Retinoic acid has previously been shown to be involved in the development of the salivary gland, and recently, lack of retinoid signaling has been shown to impact the K5+ population of basal progenitor cells. Since retinoic acid is known to exert stimulatory effects …
Expanding Our Vision : An Empirical Examination Of Security Sector Reform, Andrew Vitek
Expanding Our Vision : An Empirical Examination Of Security Sector Reform, Andrew Vitek
Legacy Theses & Dissertations (2009 - 2024)
This dissertation contributes empirical analysis on the dynamics of security sector reform and aims to establish an understanding of the interplay between civilian governments, security forces and international actors in attempts to reform the security sectors of transitioning or reconstructing states. The need for reform programs aimed at boosting civilian control over state security forces has gained increased attention following the end of the Cold War, especially for states during regime transitions or post-conflict reconstruction. The record of success for these programs however remains inconsistent, and empirical scholarship aimed at the process at the time of writing is problematically sparse.