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Cannabis Use Across The Menstrual Cycle: The Impact Of Negative Affect And Coping Motives, Paige Morris Apr 2023

Cannabis Use Across The Menstrual Cycle: The Impact Of Negative Affect And Coping Motives, Paige Morris

LSU Master's Theses

Women appear to use more cannabis during the premenstrual and menstrual phases of the menstrual cycle, presumably because women use cannabis to manage increases in negative affect associated with these phases. Yet little work has tested this hypothesis or examined individual difference variables associated with greater coping-motivated cannabis use. The current study tested whether state negative affect interacts with coping motives to predict greater cannabis use during the premenstrual and/or menstrual phases and whether trait anxiety or difficulties with emotion regulation moderate these relations. Female undergraduate students with regular monthly menstrual cycles and who were not using hormonal contraceptives ( …


Use Of A Zebrafish Model To Identify Anticonvulsant Properties Of Cannabinoid And Terpenoid Extracts And Mixtures, Courtney Murr Mar 2021

Use Of A Zebrafish Model To Identify Anticonvulsant Properties Of Cannabinoid And Terpenoid Extracts And Mixtures, Courtney Murr

LSU Master's Theses

Epilepsy is a complex group of neurological disorders affecting approximately 65 million people worldwide. Animal models reveal the activation of cannabinoid receptor 1 and cannabinoid receptor 2 reduces the severity of seizures associated with epilepsy. Trials of phytocannabinoids in mammals demonstrate their efficacy of reducing the severity of epileptic seizures. Numerous terpenoid compounds are present in Cannabis plants but most have yet to be clinically investigated. The goal of this research was to use zebrafish (Danio rerio) to identify the potential anticonvulsive properties of phytocannabinoid and terpenoid compounds. During acute cannabinoid exposures, 7-days-post-fertilization (7 dpf) zebrafish larvae were …


Social Anxiety And Cannabis-Related Impairment: The Roles Of Anxiety Sensitivity And Intolerance Of Uncertainty, Emily Robin Jeffries Jan 2015

Social Anxiety And Cannabis-Related Impairment: The Roles Of Anxiety Sensitivity And Intolerance Of Uncertainty, Emily Robin Jeffries

LSU Master's Theses

Cannabis use is associated with many negative consequences. Identification of factors associated with cannabis could inform prevention and treatment efforts. Social anxiety appears to be one risk factor for cannabis-related problems. Thus, it is important to identify malleable cognitive vulnerability factors that may play a role in the social anxiety-cannabis problems relationship. Anxiety sensitivity (AS) is the fear of anxiety-related bodily sensations and is composed of three subfacets: physical, cognitive, and social concerns. AS is associated with greater social anxiety and may play a role in cannabis-related impairment. Intolerance of uncertainty (IU) refers to a tendency to respond negatively to …