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Sense Of Place, Place Attachment, And Rootedness In Four West Baton Rouge Parish, Louisiana Bars, John Winsor Mcewen
Sense Of Place, Place Attachment, And Rootedness In Four West Baton Rouge Parish, Louisiana Bars, John Winsor Mcewen
LSU Doctoral Dissertations
This dissertation explores place and the relationships that people have with place: sense of place, place attachment, and rootedness. These three concepts have each been researched and discussed on their own in journal articles, books, and book chapters, but the terms rarely appear in the same sentence let alone the same research article. In the United States, places of drink are historically linked to community and social interactions, and such establishments often possess a solid core of loyal patrons for whom going to their bar is a natural and routine part of their daily and weekly life. This research brings …
Mechanisms Of Innate Immunity In Polymicrobial Sepsis, Liliang Jin
Mechanisms Of Innate Immunity In Polymicrobial Sepsis, Liliang Jin
LSU Doctoral Dissertations
Severe bacterial sepsis leads to a pro-inflammatory condition that can manifest as septic shock, multiple organ failure, and death. Neutrophils are critical for the rapid elimination of bacteria, however, the role of neutrophil chemoattractant CXCL1, pattern recognition receptors (PRRs)- NLR protein 3 (NLRP3) and alcohol in bacterial clearance during sepsis remains elusive. We demonstrate that CXCL1 plays a pivotal role in mediating host defense to polymicrobial sepsis following cecal ligation and puncture (CLP) in gene-deficient mice. CXCL1 appears to be essential for restricting bacterial outgrowth and preventing multiple organ failure and death in mice. Moreover, CXCL1 is essential for neutrophil …