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Stress

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Microrna As A Maternal Marker For Prenatal Stress-Associated Asd, Evidence From A Murine Model, Taeseon Woo, Candice King, Nick I. Ahmed, Madison Cordes, Saatvika Nistala, Matthew J. Will, Clark Bloomer, Nataliya Kibiryeva, Rocio M. Rivera, Zohreh Talebizadeh, David Q. Beversdorf Sep 2023

Microrna As A Maternal Marker For Prenatal Stress-Associated Asd, Evidence From A Murine Model, Taeseon Woo, Candice King, Nick I. Ahmed, Madison Cordes, Saatvika Nistala, Matthew J. Will, Clark Bloomer, Nataliya Kibiryeva, Rocio M. Rivera, Zohreh Talebizadeh, David Q. Beversdorf

Faculty Publications

Autism Spectrum Disorder (ASD) has been associated with a complex interplay between genetic and environmental factors. Prenatal stress exposure has been identified as a possible risk factor, although most stress-exposed pregnancies do not result in ASD. The serotonin transporter (SERT) gene has been linked to stress reactivity, and the presence of the SERT short (S)-allele has been shown to mediate the association between maternal stress exposure and ASD. In a mouse model, we investigated the effects of prenatal stress exposure and maternal SERT genotype on offspring behavior and explored its association with maternal microRNA (miRNA) expression during pregnancy. Pregnant female …


The Relationship Between Physical Activity, Sleep Quality, And Stress: A Study Of Teachers During The Covid-19 Pandemic, Fabio Fontana, Kelsey Bourbeau, Terence Moriarty, Michael Pereira Da Silva Dec 2022

The Relationship Between Physical Activity, Sleep Quality, And Stress: A Study Of Teachers During The Covid-19 Pandemic, Fabio Fontana, Kelsey Bourbeau, Terence Moriarty, Michael Pereira Da Silva

Faculty Publications

The COVID-19 pandemic prompted chaotic changes in the daily lives of K-12 teachers, resulting in increased stress and other mental health problems. Limited evidence regarding the relationship between physical activity, sleep, and perceived stress among teachers during the COVID-19 pandemic exists. Therefore, the purpose of this study was to investigate the association between physical activity, sleep quality, and perceived psychological stress among teachers during the COVID-19 pandemic. An online survey measuring physical activity, sleep quality, and perceived psychological stress was distributed across 47 US states between September and October of 2020. Data provided by 635 teachers (mean age: 42 ± …


Effects Of Positive And Negative Emotion On Picture Naming For People With Mild To Moderate Aphasia: A Preliminary Investigation, Tyson G. Harmon, Courtney Nielsen, Corinne Loveridge, Camille Williams Feb 2022

Effects Of Positive And Negative Emotion On Picture Naming For People With Mild To Moderate Aphasia: A Preliminary Investigation, Tyson G. Harmon, Courtney Nielsen, Corinne Loveridge, Camille Williams

Faculty Publications

Purpose: To investigate how emotional arousal and valence affect confrontational naming accuracy and response time in people with mild to moderate aphasia compared with adults without aphasia. We hypothesized that negative and positive emotions would facilitate naming for people with aphasia but lead to slower responses for adults with no aphasia.

Method: Eight participants with mild to moderate aphasia, 15 older adults, and 17 young adults completed a confrontational naming task across three conditions (positive, negative, neutral) in an ABA case series design. Immediately following each naming condition, participants self-reported their perceived arousal and pleasure. Accuracy and response time were …


Differential Relationships Of Stress And Hiv Disclosure By Gender: A Person Centered Longitudinal Study, Chengbo Zeng, Shan Qiao Ph.D., Xiaoming Li Ph.D., Xueying Yang Ph.D., Zhiyong Shen, Yuejiao Zhou Feb 2021

Differential Relationships Of Stress And Hiv Disclosure By Gender: A Person Centered Longitudinal Study, Chengbo Zeng, Shan Qiao Ph.D., Xiaoming Li Ph.D., Xueying Yang Ph.D., Zhiyong Shen, Yuejiao Zhou

Faculty Publications

Background: Existing literature mostly consider HIV disclosure as a static event and investigate its relationship with stress using a cross-sectional design. It is unclear about the dynamic changes of HIV disclosure levels (defined as the number of disclosure targets) and how stress may influence these changes. This study explored different disclosure levels using a person-centered longitudinal approach, examined whether stress could predict these disclosure levels, and investigated if this relationship differed by gender among people living with HIV (PLWH). Methods: Data were derived from a prospective cohort study conducted from November 2016 to January 2018 in Guangxi, China. Four hundred …


Increased Mood Disorder Symptoms, Perceived Stress, And Alcohol Use Among College Students During The Covid-19 Pandemic, Nora E. Charles, Stephanie J. Strong, Lauren C. Burns, Margaret R. Bullerjahn, Katherine M. Serafine Feb 2021

Increased Mood Disorder Symptoms, Perceived Stress, And Alcohol Use Among College Students During The Covid-19 Pandemic, Nora E. Charles, Stephanie J. Strong, Lauren C. Burns, Margaret R. Bullerjahn, Katherine M. Serafine

Faculty Publications

The COVID-19 pandemic caused significant disruption during the spring of 2020. Many college students were told to leave campus at spring break and to complete the semester remotely. This study evaluates effects of this disruption on student well-being. Measures of psychological symptoms, perceived stress, and alcohol use during the pandemic were completed by 148 students in spring 2020 and 352 students in fall 2020 at a university in the southeastern U.S. Results from both cohorts were compared to 240 students who completed the same measures in the fall 2019 semester. Participants in spring 2020 reported more mood disorder symptoms, perceived …


Hurricane Irma Induces Divergent Behavioral And Hormonal Impacts On An Urban And Forest Population Of Invasive Anolis Lizards: Evidence For An Urban Resilience Hypothesis, Haralambos Fokidis, Taylor Brock Jan 2021

Hurricane Irma Induces Divergent Behavioral And Hormonal Impacts On An Urban And Forest Population Of Invasive Anolis Lizards: Evidence For An Urban Resilience Hypothesis, Haralambos Fokidis, Taylor Brock

Faculty Publications

Hurricanes can have both profound short-term effects on animal populations and serve as long-term drivers of evolutionary change. Animals inhabiting varying habitats may differ in their response to hurricane impacts. Increasing evidence sug- gests that animals from urban areas exhibit different behavioral and physiological traits compared to rural counterparts, in- cluding attenuated hormonal stress responses and a lowered propensity for flight behavior. A unique opportunity was pre- sented when Hurricane Irma hit Florida on 10 September 2017 and interrupted a study of invasive brown anoles (Anolis sagrei) at an urban and a forest. Using data collected before and after Hurricane …


Framework For A Community Health Observing System For The Gulf Of Mexico Region: Preparing For Future Disasters, Paul Sandifer, Landon Knapp, Maureen Lichtveld, Ruth Manley, David Abramson, Rex Caffey, David Cochran, Tracy Collier, Kristie Ebi, Lawrence Engel, John Farrington, Melissa Finucane, Christine Hale, David Halpern, Emily Harville, Leslie Hart, Yulin Hswen, Barbara Kirkpatrick, Bruce Mcewen, Glenn Morris, Raymond Orbach, Lawrence Palinkas, Melissa Partyka, Dwayne Porter, Aric A. Prather, Teresa Rowles, Geoffrey Scott, Teresa Seeman, Helena Solo-Gabriele, Erik Svendsen, Terry Tincher, Juli Trtanj, Ann Hayward Walker Oct 2020

Framework For A Community Health Observing System For The Gulf Of Mexico Region: Preparing For Future Disasters, Paul Sandifer, Landon Knapp, Maureen Lichtveld, Ruth Manley, David Abramson, Rex Caffey, David Cochran, Tracy Collier, Kristie Ebi, Lawrence Engel, John Farrington, Melissa Finucane, Christine Hale, David Halpern, Emily Harville, Leslie Hart, Yulin Hswen, Barbara Kirkpatrick, Bruce Mcewen, Glenn Morris, Raymond Orbach, Lawrence Palinkas, Melissa Partyka, Dwayne Porter, Aric A. Prather, Teresa Rowles, Geoffrey Scott, Teresa Seeman, Helena Solo-Gabriele, Erik Svendsen, Terry Tincher, Juli Trtanj, Ann Hayward Walker

Faculty Publications

© Copyright © 2020 Sandifer, Knapp, Lichtveld, Manley, Abramson, Caffey, Cochran, Collier, Ebi, Engel, Farrington, Finucane, Hale, Halpern, Harville, Hart, Hswen, Kirkpatrick, McEwen, Morris, Orbach, Palinkas, Partyka, Porter, Prather, Rowles, Scott, Seeman, Solo-Gabriele, Svendsen, Tincher, Trtanj, Walker, Yehuda, Yip, Yoskowitz and Singer. The Gulf of Mexico (GoM) region is prone to disasters, including recurrent oil spills, hurricanes, floods, industrial accidents, harmful algal blooms, and the current COVID-19 pandemic. The GoM and other regions of the U.S. lack sufficient baseline health information to identify, attribute, mitigate, and facilitate prevention of major health effects of disasters. Developing capacity to assess adverse human …


“Toxic” Schools? How School Exposures During Adolescence Influence Trajectories Of Health Through Young Adulthood, Courtney E. Boen, Karen Kozlowski, Karolyn D. Tyson Aug 2020

“Toxic” Schools? How School Exposures During Adolescence Influence Trajectories Of Health Through Young Adulthood, Courtney E. Boen, Karen Kozlowski, Karolyn D. Tyson

Faculty Publications

© 2020 The Author(s) A large body of research identifies the critical role of early-life social contexts such as neighborhoods and households in shaping life course trajectories of health. Less is known about whether and how school characteristics affect individual health and contribute to population health inequality. However, recent scholarship argues that some school environments are so stressful due to high levels of violence, disorder, and poverty that they may be “toxic” to student health, but this hypothesis has not been tested using population data. Integrating insights from the life course perspective and stress process model, we use rich longitudinal …


Design Sizing Of Cylindrical Worm Gearsets, Edward E. Osakue, Lucky Anetor Jan 2020

Design Sizing Of Cylindrical Worm Gearsets, Edward E. Osakue, Lucky Anetor

Faculty Publications

A method for the design sizing task of cylindrical worm gearsets is presented that gives an estimate of the initial value of the normal module. Expressions are derived for the worm pitch diameter of integral and shell worms as well as for the active facewidth of the gear and the threaded length of the worm. An attempt is made to predict the contact strength of bronze materials against scoring resistance. Four Examples of design sizing tasks of cylindrical worm gears are carried out using the approach presented and the results are compared with previous solutions from other methods. The results …


A Brighter Future: The Effect Of Social Class On Responses To Future Debt, Harrison J. Schmitt, Lucas A. Keefer, Daniel Sullivan, Sheridan Stewart, Isaac F. Young Jan 2020

A Brighter Future: The Effect Of Social Class On Responses To Future Debt, Harrison J. Schmitt, Lucas A. Keefer, Daniel Sullivan, Sheridan Stewart, Isaac F. Young

Faculty Publications

© 2020, PsychOpen. All rights reserved. The present study serves as an exploratory investigation of the role of social class in responses to the threat of future debt. Previous work has shown that individuals of high and low subjective social class differ in the ways that they respond to a broad range of threats and uncertainties about the future. Across three studies, we found that lower social class individuals expect more future debt and suffer greater attendant stress than higher class individuals (Study 1). We found that experimental manipulations of debt salience increased stress for lower class and not for …


Light Emitting Diode (Led) Color And Broiler Growth: Effect Of Supplementing Blue/Green Led To White Led Light On Broiler Growth, Stress, And Welfare, Jill R. Nelson, Joey L. Bray, Juliette Delabbio, Gregory S. Archer Jan 2020

Light Emitting Diode (Led) Color And Broiler Growth: Effect Of Supplementing Blue/Green Led To White Led Light On Broiler Growth, Stress, And Welfare, Jill R. Nelson, Joey L. Bray, Juliette Delabbio, Gregory S. Archer

Faculty Publications

Light emitting diode (LED) lighting provides an affordable lighting option for use in commercial poultry production. However, more information is needed to understand the effects of LED color on broiler welfare and growth. Five consecutive flocks (1 in summer, 1 in fall, 2 in winter, and 1 in spring) of straight run Ross 708 × Ross 708 broilers were reared in commercial type barns for 45 D. For white only (WO) treatment, birds were reared under white LED only (Agrishift MLB). For white supplemented (WS) treatment, birds were reared under white LED (Agrishift MLB) in the center aisle, with supplemental …


Associations Of Ambivalent Leadership With Distress And Cortisol Secretion, Wendy C. Birmingham, Raphael M. Herr, Frenk Van Harreveld, Bert N. Uchino, Adrian Loerbroks, Joachim E. Fischer, Jos A. Bosch Jan 2019

Associations Of Ambivalent Leadership With Distress And Cortisol Secretion, Wendy C. Birmingham, Raphael M. Herr, Frenk Van Harreveld, Bert N. Uchino, Adrian Loerbroks, Joachim E. Fischer, Jos A. Bosch

Faculty Publications

Ambivalent social ties, i.e., whereby a relationship is evaluated simultaneously in positive and negative terms, are a potential source of distress and can perturb health-relevant biological functions. Social interactions at the workplace, in particular with supervisors, are often described in ambivalent terms, but the psychological and psychobiological impact of such interactions has received little scientific attention. The current study examined associations between ambivalent attitudes towards one’s supervisor, perceived distress (general and work-related), and diurnal dynamics of the stress hormone cortisol. 613 employees evaluated their supervisor in terms of positive and negative behaviors, which was combined into an ambivalent index. Higher …


Challenges, Pitfalls And Surprises: Development And Validation Of A Monoclonal Antibody For Enzyme Immunoassay Of The Steroid 1Α-Hydroxycorticosterone In Elasmobranch Species, Catharine J. Wheaton, Natalie D. Mylniczenko, John M. Rimoldi, Rama S.V.S. Gadepalli, R. Hart, Bobbi R. O'Hara, Andrew N. Evans Sep 2018

Challenges, Pitfalls And Surprises: Development And Validation Of A Monoclonal Antibody For Enzyme Immunoassay Of The Steroid 1Α-Hydroxycorticosterone In Elasmobranch Species, Catharine J. Wheaton, Natalie D. Mylniczenko, John M. Rimoldi, Rama S.V.S. Gadepalli, R. Hart, Bobbi R. O'Hara, Andrew N. Evans

Faculty Publications

Sharks and rays are popular species used in wildlife ecotourism and aquariums to educate the public on the behavior, ecology and conservation challenges of elasmobranchs. To understand long-term physiological health and welfare under varying social and husbandry conditions, we developed and validated an enzyme immunoassay (EIA) to measure stress/ionoregulatory hormones in managed and semi-free range southern rays (Hypanus americanus). Banked serum and interrenal samples from 27 female rays managed at Disney’s The Seas with Nemo and Friends® and Castaway Cay were used to evaluate measurement of 1α-hydroxycorticosterone (1αOHB) relative to corticosterone (B). Although commercial EIAs are available …


Attitudes Toward Evidence-Based Practice, Occupational Stress And Work-Related Social Support Among Health Care Providers In China: A Sem Analysis, Shan Qiao Ph.D., Xiaoming Li Ph.D., Yuejiao Zhou, Zhiyong Shen, Bonita Stanton Aug 2018

Attitudes Toward Evidence-Based Practice, Occupational Stress And Work-Related Social Support Among Health Care Providers In China: A Sem Analysis, Shan Qiao Ph.D., Xiaoming Li Ph.D., Yuejiao Zhou, Zhiyong Shen, Bonita Stanton

Faculty Publications

Individuals’ attitudes toward evidence-based practices (EBP) are critical in adopting, implementing and maintaining the EBP in clinical settings. Multiple empirical studies have examined how work context may shape perceptions and attitudes towards EBP. The current study aims to further explore how both work and family contexts, as assessed by three psychosocial indicators (i.e., occupational stress, work-related social support from coworkers, and work-related social support from family), may affect attitudes toward EBP among health care providers in HIV clinics in China. We analyzed cross-sectional survey data from 357 health care providers recruited from 40 HIV clinics across 16 cities/counties in Guangxi …


Preliminary Long-Term Health Outcomes Associated With Recreation-Based Health And Wellness Programs For Injured Service Members, Jasmine Townsend, Brent L. Hawkins, Jessie L. Bennett, Jamie Hoffman, Tamar Martin, Elaine Sotherden, William Bridges Mar 2018

Preliminary Long-Term Health Outcomes Associated With Recreation-Based Health And Wellness Programs For Injured Service Members, Jasmine Townsend, Brent L. Hawkins, Jessie L. Bennett, Jamie Hoffman, Tamar Martin, Elaine Sotherden, William Bridges

Faculty Publications

Recreation-based health and wellness programs for military service members are currently a topic of significant interest in the recreation and health industries. This study examined the health outcomes associated with participation in Project Sanctuary, a week-long recreation-based health and wellness family retreat for injured military service members. Linear mixed modeling was used to examine changes in health outcomes over four time points, and considered multiple covariates. One-hundred twenty-seven service members participated. Statistically significant reductions in total scores for Post-Traumatic Stress Disorder Checklist (PCL) measures were found, as well as notable improvements in Depression, Anxiety, and Atress Scale (DASS) and mental …


Analysis Of Endocrine Response To Perceived Difference In Cross-Cultural Interactions, Carole Woolford-Hunt, Marlene Murray, Tevni Grajales Guerra, Kristina Beenken-Johnson Jan 2018

Analysis Of Endocrine Response To Perceived Difference In Cross-Cultural Interactions, Carole Woolford-Hunt, Marlene Murray, Tevni Grajales Guerra, Kristina Beenken-Johnson

Faculty Publications

We live in a world where awareness of ethnic and cultural diversity is an ever increasing reality. Business and education turn to the social sciences to inform them about how to manage and optimize cross-cultural interactions. Although much research has been done on the impact of cross-cultural interactions on a wide range of variables, one less researched area is the endocrine response to cross-cultural interactions. In this study we set out to investigate the endocrine response to cross cultural interactions and the impact of these interactions on perceived differences. To do so we measured the pre and post levels of …


Relationship Between Physical Activity And Stress Among Junior High School Students In The Physical Education Environment, David C. Barney, Frank Pleban, Terrance Lewis Dec 2017

Relationship Between Physical Activity And Stress Among Junior High School Students In The Physical Education Environment, David C. Barney, Frank Pleban, Terrance Lewis

Faculty Publications

The study purpose was to explore grade level differences (7th, 8th, and 9th) among junior high school students’ perception of participation in physical education class on individual environmental stress. Physical activity’s role as a stress reduction tool has been well documented. However, physical activity as a stressful event in the school and physical education environment has been less established; particularly in junior high school students. Study participants were comprised of 872 junior high school students, 585 males (67%) and 287 females (33%), enrolled in four junior high schools. Stratified by grade, 315 7th …


Early Rearing History Influences Oxytocin Receptor Epigenetic Regulation In Rhesus Macaques, Maggie Baker, Stephen G. Lindell, Carlos A. Driscoll, Zhifeng Zhou, Qiaoping Yuan, Melanie L. Schwandt, Isaac Miller-Crews, Elizabeth A. Simpson, Annika Paukner, Pier Francesco Ferrari, Ravi Kumar Sindhu, Muslima Razaqya, Wolfgang H. Sommer, Juan F. Lopez, Robert C. Thompson, David Goldman, Markus Heilig, J. Dee Higley, Stephen J. Suomi, Christina S. Barr Sep 2017

Early Rearing History Influences Oxytocin Receptor Epigenetic Regulation In Rhesus Macaques, Maggie Baker, Stephen G. Lindell, Carlos A. Driscoll, Zhifeng Zhou, Qiaoping Yuan, Melanie L. Schwandt, Isaac Miller-Crews, Elizabeth A. Simpson, Annika Paukner, Pier Francesco Ferrari, Ravi Kumar Sindhu, Muslima Razaqya, Wolfgang H. Sommer, Juan F. Lopez, Robert C. Thompson, David Goldman, Markus Heilig, J. Dee Higley, Stephen J. Suomi, Christina S. Barr

Faculty Publications

Adaptations to stress can occur through epigenetic processes and may be a conduit for informing offspring of environmental challenge. We employed ChIP-sequencing for H3K4me3 to examine effects of early maternal deprivation (peer-rearing, PR) in archived rhesus macaque hippocampal samples (male, n = 13). Focusing on genes with roles in stress response and behavior, we assessed the effects of rearing on H3K4me3 binding by ANOVA. We found decreased H3K4me3 binding at genes critical to behavioral stress response, the most robust being the oxytocin receptor gene OXTR, for which we observed a corresponding decrease in RNA expression. Based on this finding, we …


Preadolescent Sensation Seeking And Early Adolescent Stress Relate To At-Risk Adolescents' Substance Use By Age 15, Nora E. Charles, Charles W. Mathias, Ashley Acheson, Donald M. Dougherty Jun 2017

Preadolescent Sensation Seeking And Early Adolescent Stress Relate To At-Risk Adolescents' Substance Use By Age 15, Nora E. Charles, Charles W. Mathias, Ashley Acheson, Donald M. Dougherty

Faculty Publications

Background and aims

Substance use during adolescence can lead to the development of substance use disorders and other psychosocial problems. These negative outcomes are especially likely for individuals who use substances at earlier ages and those who engage in heavier use during adolescence, behaviors which are both more common among youth at higher risk for developing a substance use disorder, such as those with a family history of substance use disorders (FH +). Factors such as increased sensation seeking and greater exposure to stressors among FH + youth may influence these associations. Therefore, the aim of this study was to …


Stress Buffer Or Identity Threat?: Negative Media Portrayal, Public And Private Religious Involvement, And Mental Health In A National Sample Of Us Adults, Samuel Stroope, Mark H. Walker, Aaron B. Franzen Mar 2017

Stress Buffer Or Identity Threat?: Negative Media Portrayal, Public And Private Religious Involvement, And Mental Health In A National Sample Of Us Adults, Samuel Stroope, Mark H. Walker, Aaron B. Franzen

Faculty Publications

Guided by the stress process tradition, complex links between religion and mental health have received growing attention from researchers. This study gauges individuals’ public and private religiosity, uses a novel measure of environmental stress—negative media portrayal of religion—and presents two divergent hypotheses: (1) religiosity as stress-exacerbating attachment to valued identities producing mental health vulnerability to threat and (2) religiosity as stress-buffering social psychological resource. To assess these hypotheses, we analyze three mental health outcomes (generalized anxiety, social anxiety, and general mental health problems) in national U.S. data from 2010 (N = 1,714). Our findings align with the stress-buffering perspective. Results …


Hair Measurements Of Cortisol, Dhea, And Dhea To Cortisol Ratio As Biomarkers Of Chronic Stress Among People Living With Hiv In China: Known-Group Validation, Shan Qiao Ph.D., Xiaoming Li, Samuele Zilioli, Zheng Chen, Huihua Deng, Juxian Pan, Weigui Guo Jan 2017

Hair Measurements Of Cortisol, Dhea, And Dhea To Cortisol Ratio As Biomarkers Of Chronic Stress Among People Living With Hiv In China: Known-Group Validation, Shan Qiao Ph.D., Xiaoming Li, Samuele Zilioli, Zheng Chen, Huihua Deng, Juxian Pan, Weigui Guo

Faculty Publications

Background

Existing literature suggests that endocrine measures, including the steroid hormones of cortisol and Dehydroepiandrosterone (DHEA), as well as the DHEA to cortisol ratio in the human hair can be used as promising biomarkers of chronic stress among humans. However, data are limited regarding the validity of these measures as biomarkers of chronic stress among people living with HIV (PLWH), whose endocrine system or hypothalamic pituitary adrenal (HPA) axis may be affected by HIV infection and/or antiretroviral therapy (ART) medications.

Method

Using hair sample data and self-reported survey from 60 PLWH in China, we examined the validity of three endocrine …


Preliminary Identification Of Coping Profiles Relevant To Surrogate Decision Making In The Icu, Jorie M. Butler, Eliotte L. Hirshberg, Ramona O. Hopkins, Emily L. Wilson, James F. Orme, Sarah J. Beesley, Kathryn Kuttler, Samuel M. Brown Nov 2016

Preliminary Identification Of Coping Profiles Relevant To Surrogate Decision Making In The Icu, Jorie M. Butler, Eliotte L. Hirshberg, Ramona O. Hopkins, Emily L. Wilson, James F. Orme, Sarah J. Beesley, Kathryn Kuttler, Samuel M. Brown

Faculty Publications

Objective The Intensive Care Unit (ICU) is a stressful environment for families of critically ill patients and these individuals are at risk to develop persistent psychological morbidity. Our study objective was to identify individual differences in coping with stress and information presentation preferences of respondents exposed to a simulated ICU experience.

Methods Participants were recruited from a university and two community populations. Participants completed questionnaires that measured demographic information and characteristics that may be relevant to an individual’s ICU experience. Quality of life was measured by the EQ5D, personality dimensions were examined with the abbreviated Big Five inventory, coping with …


Effects Of Hypoxia And Elevated Ammonia Concentration On The Viability Of Red Snapper Embryos And Early Larvae, Agnes Bardon-Albaret, Eric A. Saillant Jun 2016

Effects Of Hypoxia And Elevated Ammonia Concentration On The Viability Of Red Snapper Embryos And Early Larvae, Agnes Bardon-Albaret, Eric A. Saillant

Faculty Publications

The effects of hypoxic conditions and elevated ammonia concentrations on the viability of embryos and newly hatched larvae of the red snapper (Lutjanus campechanus) were investigated. In all experiments, tested levels of hypoxia or ammonia concentrationswere applied to embryos and unfed newly hatched larvae from three different spawns. Exposures began at 1 h post fertilization (pf) and lasted until all individuals in a group had expired. Survival rates were monitored daily in duplicates for each spawn in each treatment. Fertilized eggs exposed to 2 mg L-1 dissolved oxygen (29% saturation) showed complete mortality before hatch while 81% of embryos in …


Biomechanical Implications Of Intraspecific Shape Variation In Chimpanzee Crania: Moving Toward An Integration Of Geometric Morphometrics And Finite Element Analysis, Amanda L. Smith, Stefano Benazzi, Justin A. Ledogar, Kelli Tamvada, Leslie C. Pryor Smith, Gerhard W. Weber, Mark A. Spencer, Paul C. Dechow, Ian R. Grosse, Callum F. Ross, Brian G. Richmond, Barth Wright, Qian Wang, Dennis E. Slice, David S. Strait Jan 2015

Biomechanical Implications Of Intraspecific Shape Variation In Chimpanzee Crania: Moving Toward An Integration Of Geometric Morphometrics And Finite Element Analysis, Amanda L. Smith, Stefano Benazzi, Justin A. Ledogar, Kelli Tamvada, Leslie C. Pryor Smith, Gerhard W. Weber, Mark A. Spencer, Paul C. Dechow, Ian R. Grosse, Callum F. Ross, Brian G. Richmond, Barth Wright, Qian Wang, Dennis E. Slice, David S. Strait

Faculty Publications

In a broad range of evolutionary studies, an understanding of intraspecific variation is needed in order to contextualize and interpret the meaning of variation between species. However, mechanical analyses of primate crania using experimental or modeling methods typically encounter logistical constraints that force them to rely on data gathered from only one or a few individuals. This results in a lack of knowledge concerning the mechanical significance of intraspecific shape variation that limits our ability to infer the significance of interspecific differences. This study uses geometric morphometric methods (GM) and finite element analysis (FEA) to examine the biomechanical implications of …


Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley Jul 2014

Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley

Faculty Publications

Background—Studies show that the hypothalamic–pituitary–adrenal (HPA) axis is dysregulated in depression. Some studies suggest that variation in the serotonin transporter genotype (hereafter 5HTT) modulates both risk for depression and psychopathological HPA axis responsiveness. Rhesus monkeys are well suited to model such relationships. Rhesus macaque models of human psychopathology have assessed the effect of the serotonin transporter (rh5HTT) on levels of cortisol in stressed subjects. These studies show that that under conditions of stress, heterozygous females (Ls) reared under adversity exhibit high levels of cortisol. Studies have not to our knowledge, however, assessed the potential additive effect on the cortisol response …


Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley Jul 2014

Serotonin Transporter Genotype Modulates Hpa Axis Output During Stress: Effect Of Stress, Dexamethasone Test And Acth Challenge, Andrea N. Sorenson, Erin C. Sullivan, Sally P. Mendoza, John P. Capitanio, James Dee Higley

Faculty Publications

Background—Studies show that the hypothalamic–pituitary–adrenal (HPA) axis is dysregulated in depression. Some studies suggest that variation in the serotonin transporter genotype (hereafter 5HTT) modulates both risk for depression and psychopathological HPA axis responsiveness. Rhesus monkeys are well suited to model such relationships. Rhesus macaque models of human psychopathology have assessed the effect of the serotonin transporter (rh5HTT) on levels of cortisol in stressed subjects. These studies show that that under conditions of stress, heterozygous females (Ls) reared under adversity exhibit high levels of cortisol. Studies have not to our knowledge, however, assessed the potential additive effect on the cortisol response …


Early Prenatal Food Supplementation Ameliorates Thenegative Association Of Maternal Stress With Birth Size In A Randomised Trial, Amy L. Frith, Ruchira T. Naved, Lars Ake Persson, Edward A. Frongillo Jr. Apr 2013

Early Prenatal Food Supplementation Ameliorates Thenegative Association Of Maternal Stress With Birth Size In A Randomised Trial, Amy L. Frith, Ruchira T. Naved, Lars Ake Persson, Edward A. Frongillo Jr.

Faculty Publications

Low birthweight increases the risk of infant mortality, morbidity and poor development. Maternal nutrition and stress influence birth size, but their combined effect is not known.We hypothesised that an early-invitation time to start a prenatal food supplementation programme could reduce the negative influence of prenatal maternal stress on birth size, and that effect would differ by infant sex. A cohort of 1041 pregnant women, who had delivered an infant, June 2003–March 2004, was sampled from among 3267 in the randomised controlled trial, Maternal Infant Nutritional Interventions Matlab, conducted in Matlab, Bangladesh. At 8 weeks gestation, women were randomly assigned an …


Respite Care, Marital Quality, And Stress In Parents Of Children With Autism Spectrum Disorders, Amber Harper, Tina Taylor, James Harper, Susanne Olsen Roper, Mikle South Jan 2013

Respite Care, Marital Quality, And Stress In Parents Of Children With Autism Spectrum Disorders, Amber Harper, Tina Taylor, James Harper, Susanne Olsen Roper, Mikle South

Faculty Publications

Parents of children with autism spectrum disorders (ASD) are at risk for having higher stress and lower marital quality than other parents. Survey data regarding respite care, marital quality, and daily hassles and uplifts were obtained from 101 mother-father dyads who were together raising at least one child with ASD (total # of children = 118). Number of hours of respite care was positively related to improved marital quality for both husbands and wives, such that a one-hour increase in weekly respite care was associated with a one-half standard deviation increase in marital quality. This relationship was significantly mediated by …


Oprm1 Gene Variation Influences Hypothalamic-Pituitary-Adrenal Axis Function In Response To A Variety Of Stressors In Rhesus Macaques, Melanie L. Schwandt, Stephen G. Lindell, James Dee Higley, Stephen J. Suomi, Markus Heilig, Christina S. Barr Oct 2012

Oprm1 Gene Variation Influences Hypothalamic-Pituitary-Adrenal Axis Function In Response To A Variety Of Stressors In Rhesus Macaques, Melanie L. Schwandt, Stephen G. Lindell, James Dee Higley, Stephen J. Suomi, Markus Heilig, Christina S. Barr

Faculty Publications

The endogenous opioid system is involved in modulating a number of behavioral and physiological systems, including the hypothalamic-pituitary-adrenal (HPA) axis. In humans, a functional variant in the OPRM1 gene (OPRM1 A118G) is associated with a number of outcomes, including attenuated HPA axis responses to stress. A nonsynonymous variant (OPRM1 C77G) in the rhesus macaque has been shown to have similar effects in vivo to the human variant. The current study investigated whether OPRM1 C77G influences HPA axis response to stress in rhesus macaques. We analyzed plasma adrenocorticotropic hormone (ACTH) and cortisol levels measured in response to three different stressors: 1) …


The Influence Of Depressive Symptomatology And Perceived Stress On Plasma And Salivary Oxytocin Before, During And After A Support Enhancement Intervention, Wendy C. Birmingham, Julianne Holt-Lunstad, Kathleen C. Light Jan 2011

The Influence Of Depressive Symptomatology And Perceived Stress On Plasma And Salivary Oxytocin Before, During And After A Support Enhancement Intervention, Wendy C. Birmingham, Julianne Holt-Lunstad, Kathleen C. Light

Faculty Publications

Oxytocin (OT) activity increases in response to stress as well as to warm social contact. Subclinical depression is associated with higher stress but less reward from social contacts. The present investigation was intended to examine whether husbands and wives with high depressive symptomatology scores have increased plasma and salivary OT that may be mediated partly by higher perceived stress, and also to assess whether an intervention to convey partner support through ‘‘warm touch’’ may reduce effects of depressive symptoms on OT. In this study, 34 healthy married couples (n = 68) ages 20—39 provided self reports of depressive symptoms (CESD) …