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The Tapestry Of Memory, Kathryn M. Lawson Aug 2017

The Tapestry Of Memory, Kathryn M. Lawson

Electronic Thesis and Dissertation Repository

Rationality points to the complete annihilation and end of a life when the body perishes, and yet when a loved one dies we continue to experience that person in a myriad of ways. The focus of this thesis will be a phenomenological exploration of the earthly afterlife of those we have loved and lost. By positing the subject as always intersubjective and as temporal in nature, this thesis will investigate how we continue to create and interact with the deceased upon the earth. In the introduction, this work will be placed in the context of the phenomenological tradition. The first …


Mechanisms Involved In The Assessment Of Cumulative Long-Term Familiarity Of Object Concepts: An Erp Study, Haopei Yang Aug 2017

Mechanisms Involved In The Assessment Of Cumulative Long-Term Familiarity Of Object Concepts: An Erp Study, Haopei Yang

Electronic Thesis and Dissertation Repository

We investigated the sensitivity of ERP components implicated in recognition memory to degree of experimentally controlled and lifetime cumulative exposures during explicit memory judgements. A parietally distributed ERP component spanning both the FN400/N400 and the LPC time windows tracked both types of judgements. This effect appears to be an LPC effect with an early onset, and differs from previously reported effects of repetition linked to implicit memory. Based on recent evidence, we interpreted it as response-related evidence accumulation processes that are in line with both single-process models and continuous dual-process models. We also observed more positive ERPs in the left …


Individual Differences In The Allocation Of Visual Attention During Navigation, Mikayla Keller Jul 2017

Individual Differences In The Allocation Of Visual Attention During Navigation, Mikayla Keller

Electronic Thesis and Dissertation Repository

There are large individual differences in the ability to create an accurate mental representation (i.e., a cognitive map) of a novel environment, yet the factors underlying cognitive map accuracy remain unclear. Given the roles that landmarks and cognitive map accuracy play in successful navigation, the current study examined whether differences in the landmarks that individuals look at while navigating are related to differences in cognitive map accuracy. Participants completed a battery of spatial tests: some that assessed spatial skills prior to a navigation task, and others that tested memory for the environment following exploration of a virtual world. Results indicated …


Cerebral Lactate Metabolism And Memory: Implications For Alzheimer's Disease, Richard Andrew Harris Apr 2017

Cerebral Lactate Metabolism And Memory: Implications For Alzheimer's Disease, Richard Andrew Harris

Electronic Thesis and Dissertation Repository

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by amyloid plaques that are comprised of aggregated amyloid-beta peptides. These toxic proteins promote mitochondrial dysfunction and neuronal cell death. A shift in metabolism away from oxidative phosphorylation and toward aerobic glycolysis, with the concomitant production of lactate, affords neurons a survival advantage against amyloid-beta toxicity. Recent evidence now suggests that aerobic glycolysis in the brain plays a critical role in supporting synaptic plasticity, learning, and memory. However, the role of aerobic glycolysis and lactate metabolism in AD-mediated cognitive decline is unknown. My objective was to test the hypotheses that aerobic glycolysis …