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A Case Study Of Single-Sex Biology Classes In A High School In South Georgia, Robert Huston Costlow
A Case Study Of Single-Sex Biology Classes In A High School In South Georgia, Robert Huston Costlow
Electronic Theses and Dissertations
The research on single-sex classrooms, especially in high schools, is at best, sparse. Settings and findings vary so dramatically from one area to another that correlating studies is difficult. However, with the advent of No Child Left Behind (2001), schools have been given the opportunity to explore new and creative ways to increase student achievement. Single-sex classrooms are one of the ways schools across the country are attempting to meet the criteria of NCLB. Some single-sex studies have shown that female students improve test scores in areas that are generally thought of as male-dominated areas, such as math and science; …
Determinants And Developmental Consequences Of Organic Contaminant Uptake In Nestling Insectivorous Birds, Mary Sebastian
Determinants And Developmental Consequences Of Organic Contaminant Uptake In Nestling Insectivorous Birds, Mary Sebastian
Electronic Theses and Dissertations
This research assesses the ecotoxicology of three avian species in their natural environment. Field studies investigated potential toxicological effects of organochlorine pollutants including polychlorinated biphenyls (PCBs) and dichlorodiphenyl trichloroethane (DDT) and their metabolites on wildlife with passerine nestlings as model organisms. For organisms at higher trophic levels, especially terrestrial ones the major route of exposure to persistent pollutants is food. Consequently, I estimated the diet of nestlings of populations of three species - tree swallows (Tachycineta bicolour), purple martins (Progne subis) and house wrens (Troglodytes aedon) at Point Pelee National Park, Ontario, Canada and their contaminant contents. Another route of …
The Role Of Spy1 Protein Regulation In Breast Cancer, Mohammad Al Sorkhy
The Role Of Spy1 Protein Regulation In Breast Cancer, Mohammad Al Sorkhy
Electronic Theses and Dissertations
Cell growth and proliferation are tightly controlled by the cyclic regulation of the cyclin dependent kinases (Cdks). Cdks are positively regulated through interactions with regulatory Cyclin partners as well as being negatively regulated through interactions with families of Cdk inhibitors (CKIs). The Spy1/RINGO family of proteins have emerged as a unique class of Cyclin-like proteins capable of directly binding both to the Cdks, as a positive regulatory partner, as well as to at least one member of the CKI's, p27Kip1, as a negative regulator. Abnormally elevated levels of Spy1 promote cell proliferation, nhibit apoptosis and are implicated in aggressive tumorgenesis …
Studies Of Olfactory Sensory Neurons In Two Invasive Fish Species, Alyson Laframboise
Studies Of Olfactory Sensory Neurons In Two Invasive Fish Species, Alyson Laframboise
Electronic Theses and Dissertations
Fishes widely employ the olfactory sense for communication in most aspects of their life. The olfactory system of fishes contains olfactory sensory neurons (OSNs) of three polymorphisms – ciliated, microvillous and crypt. This thesis describes various studies of the properties of OSNs, from the expression of polymorphisms to odour responses, receptor specificity and second messengers, in two species of invasive fish: the sea lamprey (Petromyzon marinus) and the round goby (Neogobius melanostomus). I describe, for the first time, the expression of ciliated OSNs displaying polymorphisms in the sea lamprey, an ancient jawless fish. In the round goby, I investigate the …
Role Of Cks85a In Cell Cycle Regulation, Mohammad Ghorbani
Role Of Cks85a In Cell Cycle Regulation, Mohammad Ghorbani
Electronic Theses and Dissertations
The transition between different stages of the cell cycle needs the activation of Cdk/Cyclins. SCFSkp2 ubiquitin ligase complex plays a critical role in entry into the S-phase by activating the Cdk2/Cyclin E complex. Cks85A interacts with Skp2 and helps it in recognition of the SCFSkp2 ubiquitin ligase targets. Knocking out of Cks85A and Skp2 has an effect on growth in Drosophila by reducing the cell volume in endoreplicating tissues. In this study, I have shown that the Cks85A and Skp2 null mutant larvae are smaller due to DNA replication defects in endoreplicating cells. I have shown that there is polyploidy …
Sediment Oxygen Demand And Sediment Nutrient Content Of Reclaimed Wetlands In The Oil Sands Region Of Northeastern Alberta, Carsten Slama
Sediment Oxygen Demand And Sediment Nutrient Content Of Reclaimed Wetlands In The Oil Sands Region Of Northeastern Alberta, Carsten Slama
Electronic Theses and Dissertations
Sediment oxygen demand (SOD), nutrient concentrations, and submergent macrophyte biomass were measured in reference wetlands and oil sands process material-affected (OSPM) wetlands in the oil sands region of Alberta. Any or all of these factors could influence the success of wetland reclamation in this area. Gas flux and SOD chambers were deployed to determine the biological and chemical components. Nutrient concentrations were estimated from water and sediment extractions as well as PRS™ probes.Sediment oxygen demand was slightly higher in OSPM-affected wetlands than in reference wetlands. Over 85% of SOD was due to chemical processes, likely due to ammonium oxidation. High …
The Role Of Spy1 In Mammary Morphogenesis, Agnes Malysa
The Role Of Spy1 In Mammary Morphogenesis, Agnes Malysa
Electronic Theses and Dissertations
Cell growth and development is regulated by the cell division cycle, which dictates how efficiently cells communicate with each other and is dependent on cellular morphology. Our lab focuses on a novel cell cycle regulator, Spy1A, which has been shown to enhance cellular proliferation and regulate mammary development. Elevated levels of Spy1A significantly increased cell invasion, coincident with an increase beta-catenin transcriptional levels. We hypothesize that these characteristics may maintain cells in a more & "stem-like" state. Mammary stem cells are highly proliferative, they rely on adherence to surrounding cells for self renewal and invasion and migration into the mammary …
Elucidating The Role Of Spy1a During C-Myc Induced Mammary Tumor Development, Evangelia Kirou
Elucidating The Role Of Spy1a During C-Myc Induced Mammary Tumor Development, Evangelia Kirou
Electronic Theses and Dissertations
Speedy (Spy1A) is a novel cell cycle gene whose product binds to cyclin-dependent kinase-2 (CDK2) and activates its kinase activity to promote cell cycle progression through a cyclin independent mechanism. Spy1A is expressed naturally at high levels in the proliferating mammary gland, and aberrant overexpression of Spy1A results in precocious mammary development and eventually tumorigenesis in vivo. Induction of the mammary oncogene c-Myc upregulates Spy1A and I further demonstrate that Spy1A protein levels are elevated in mammary tissue and breast tumors derived from MMTV-Myc transgenic mice. Spy1A knockdown in F5A1-2 cell lines led to downregulation of cyclin-dependent kinase inhibitors (CKI) …