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Biomechanics Of Prosthetic Knee Systems : Role Of Dampening And Energy Storage Systems, Hande Argunsah Bayram
Biomechanics Of Prosthetic Knee Systems : Role Of Dampening And Energy Storage Systems, Hande Argunsah Bayram
ETD Archive
One significant drawback of the commercial passive and microprocessored prosthetic devices, the inability of delivering positive energy when needed, is due to the absence of the knee flexion during stance phase. Moreover, consequences such as circumduction and disturbed gait pattern take place due to the improper energy flow at the knee and the absence of the positive energy delivery during the swing phase. Current generation powered design has solved these problems by delivering the needed energy with heavy battery demanding motors, which increase the mass of the device significantly. Hence, the gait quality of transfemoral amputees has not improved significantly …
Scalp Eeg And Tms Based Electrophysiological Study Of Brain Function Of Motor Control In Aging, Mehmed Satuk Bayram
Scalp Eeg And Tms Based Electrophysiological Study Of Brain Function Of Motor Control In Aging, Mehmed Satuk Bayram
ETD Archive
Voluntary movements of human body are controlled by the brain through corticomuscular pathways. Although neuromuscular control mechanisms of voluntary movements have been studied extensively, many remain to be learned, especially neuromuscular adaptations related to clinical conditions such as neurological disorders and aging. This research aims at a better understanding of functional connection between the brain and muscle during voluntary motor activities in aging and the extent to which this connection can be changed by training the neuromuscular system. Three research projects were conducted to achieve this aim. The analyses in the first two projects are based on comparisons of non-invasive …
Regulation Of Antigenic Variation In Trypanosoma Brucei, Imaan A. Benmerzouga
Regulation Of Antigenic Variation In Trypanosoma Brucei, Imaan A. Benmerzouga
ETD Archive
Trypanosoma brucei is a protozoan parasite that causes sleeping sickness in humans and nagana in cattle. When inside the mammalian host, T. brucei cells stay in extracellular spaces and regularly switch their surface antigen, Variant Surface Glycoprotein (VSG), to escape the host's immune responses. To ensure the effectiveness of VSG switching, T. brucei expresses a single type of VSG at any time exclusively from one of 20 identical VSG expression sites located next to the telomere. Monoallelic expression of VSG and VSG switching are important for T. brucei's pathogenesis. Our major goal is to understand the mechanisms of antigenic variation …
Electrochemical/Electroflotation Process For Dye Wastewater Treatment, Erick Benjamin Butler
Electrochemical/Electroflotation Process For Dye Wastewater Treatment, Erick Benjamin Butler
ETD Archive
The use of dyes has become very significant across various industries such as textiles, paper, and clothing. The organic chemical composition of dyes is a major concern when discharging wastewater not only into the environment, but also within wastewater treatment plants. Dye effluent consists of high chemical oxygen demand (COD) and also color, components that require treatment before discharge. As a result, federal legislation has required industries that discharge high components in wastewater to undergo treatment within the plants. Within literature, authors have considered various biological, physical, and chemical methods of treating dye wastewater. Recently, electrocoagulation/electroflotation (ECF) has been an …
An In Silico Liver: Model Of Gluconeogenesis, Elie R. Chalhoub
An In Silico Liver: Model Of Gluconeogenesis, Elie R. Chalhoub
ETD Archive
An in silico liver was developed in attempt to represent the in vivo state of the fasted liver. It featured two conceptual models. The first one represented carbohydrate metabolism of the human liver, which included the heterogeneous nature of the liver by incorporating spatial variation of key enzyme activities. This model was able to predict the overall fluxes in tissue and the effect of high intensity exercise on the various hepatic fluxes. A second model of hepatic metabolism was developed to represent the complex interplay between gluconeogenesis, lipid metabolism, and alcohol metabolism in the fasted rat liver. Biochemical pathways are …
A Robotic Neuro-Musculoskeletal Simulator For Spine Research, Robb W. Colbrunn
A Robotic Neuro-Musculoskeletal Simulator For Spine Research, Robb W. Colbrunn
ETD Archive
An influential conceptual framework advanced by Panjabi represents the living spine as a complex neuromusculoskeletal system whose biomechanical functioning is rather finely dependent upon the interactions among and between three principal subsystems: the passive musculoskeletal subsystem (osteoligamentous spine plus passive mechanical contributions of the muscles), the active musculoskeletal subsystem (muscles and tendons), and the neural and feedback subsystem (neural control centers and feedback elements such as mechanoreceptors located in the soft tissues) [1]. The interplay between subsystems readily encourages "thought experiments" of how pathologic changes in one subsystem might influence another--for example, prompting one to speculate how painful arthritic changes …
A Meta-Analysis Of The Effectiveness Of Stem-Programs In The United States, Dayoung An
A Meta-Analysis Of The Effectiveness Of Stem-Programs In The United States, Dayoung An
ETD Archive
The federal government has been spending a large amount of funds on STEM programs. It is important to examine the effectiveness of such spending. Much research has been conducted in the past 30 years for this particular purpose however, the results of such evaluations have not painted a clear picture of the effectiveness of STEM programs. The goal of this meta-analysis is to investigate whether STEM programs are successful in the outcomes they claim to achieve. Such a meta-analysis must integrate all of the empirical studies which reported their effort in evaluating the effectiveness of STEM programs, based on measures …
Women Pursuing Nontraditional Careers : A Social Cognitive Career Theory Perspective, Julia A. Ericksen
Women Pursuing Nontraditional Careers : A Social Cognitive Career Theory Perspective, Julia A. Ericksen
ETD Archive
Women pursuing nontraditional careers face many obstacles and constraints that can limit or impede their career development. Those who wish to participate in trades and construction occupations must often overcome the absence of meaningful learning experiences and role models, weak self-efficacy beliefs, uncertain outcome expectations along with cultural and institutional barriers. Social Cognitive Career Theory (SCCT Lent, Brown, & Hackett, 1994) provides a theoretical framework to study the career development of these women. The learning experiences, self-efficacy beliefs, and outcome expectations of 73 women with expressed Realistic interests were examined to further illuminate their career interest development. Results of this …
Development Of Quantitative Bioanalytical Methods For The Pharmacological Studies Of Anti-Cancer Drugs, Ye Feng
ETD Archive
In the anticancer drug discovery and therapy development, it is essential to understand the pharmacological properties of the drugs. Today, pharmaceutical analysis is employed throughout the whole drug discovery and development process. Pharmacokinetic-pharmacodynamic relationships are playing an increasingly important role in decisions on the rational development and use of new drugs and they can provide a detailed knowledge of the mechanism of the drug and a better understanding of the molecular targets on which they act. Due to the significance of pharmacological analysis, sensitive analytical methods are critically needed for pharmacological studies. Therefore, our long-term goal is to provide guidelines …
Boundary Spanner Role Conflict In Public Urban Universities, Joseph Gauntner
Boundary Spanner Role Conflict In Public Urban Universities, Joseph Gauntner
ETD Archive
Universities are increasingly seeking partnerships with external organizations for student learning and inter-organizational access to resources (Austin, 2010 Sandmann, 2006). The focus of such partnerships includes employee training, business development, affordable housing, community schools, community health centers, and other projects of reciprocal value to both the universities and community partners. Such work is frequently labeled university-community engagement (Carnegie Foundation, 2007). University staff members who build and sustain partnerships between their institutions and the broader community are referred to as boundary spanners (AASCU, 2004). Working as agents of the institution, a boundary spanner must be capable of working both sides of …
The Cheerful Giver :;Altruistic Activity Engagement And Happiness In Older Adult Residents Of Long-Term Care, Jessica L. Haberman
The Cheerful Giver :;Altruistic Activity Engagement And Happiness In Older Adult Residents Of Long-Term Care, Jessica L. Haberman
ETD Archive
Since the passing of the Older Americans Act in 1965 and the Federal Nursing Home Reform Act in 1987, research has shown that engagement in both social and altruistic activities may be successful interventions for maintaining and improving the well-being of nursing home residents. Research is needed, however, to compare these two types of engagement. The goal of the current study, therefore, is to address this need by answering the following questions: (1) Does engagement in altruistic activities predict change in happiness for older adult nursing home residents? Furthermore, what other factors predict changes in happiness in this population? (2) …
Exploring The Influence Of Collaborative Capabilities On Focal Firm Product Outcomes ;The Mediating Role Of Supplier Capabilities, Kenneth D. Hall
Exploring The Influence Of Collaborative Capabilities On Focal Firm Product Outcomes ;The Mediating Role Of Supplier Capabilities, Kenneth D. Hall
ETD Archive
As markets become more turbulent, dynamic, and competitive, and as customers become more sophisticated and demanding, the scope of capabilities and resources needed to meet customer needs, wants, and desires are less likely to be found in any one firm. Instead, firms must develop strong collaborative capabilities. Though the benefits of interfirm collaboration for focal firms (the firms responsible for the final offering) and suppliers are reasonably well understood, effectiveness and efficiency in collaboration remain elusive for many firms. It is likely that the collaborative capabilities of both focal firms and key suppliers contribute to effective collaboration, and that the …
The Intersection Of Policies, Practices And Perceptions Pertaining To Literacy In High School, Mary F. Handley
The Intersection Of Policies, Practices And Perceptions Pertaining To Literacy In High School, Mary F. Handley
ETD Archive
In recent years there has been an intense focus on literacy acquisition at the elementary school level. There is indisputable evidence correlating early reading achievement and future academic success. This evidence has resulted in Federal and local dollars being poured into school districts annually to insure the development of these essential skills. Frequently these dollars address instructional strategies, innovative programs professional development for teachers to improve pedagogy and their impact is measured by teachers using a variety of assessment. Due to this practice, we fail to measure, track, and provide intervention for those who are reading below grade level once …
Optimization Of Gradient Chromatofocusing For The Protein Separation And Lc-Ms/Ms Determination Of Ngp1-01 In Mouse Serum, Brain, And Retina, Harini Jogiraju
Optimization Of Gradient Chromatofocusing For The Protein Separation And Lc-Ms/Ms Determination Of Ngp1-01 In Mouse Serum, Brain, And Retina, Harini Jogiraju
ETD Archive
No abstract provided.
Factors That Contribute To Effectiveness Of Foster Care Networks In Securing Permanency For Children: An Exploration Of Network Participants' Perceptions In Urban And Rural Settings, Reza M. Khoramshahi
Factors That Contribute To Effectiveness Of Foster Care Networks In Securing Permanency For Children: An Exploration Of Network Participants' Perceptions In Urban And Rural Settings, Reza M. Khoramshahi
ETD Archive
The purpose of this study was to identify possible factors that may contribute to the variations in effectiveness of foster care networks in a rural and an urban Ohio county. The effectiveness of the networks was assessed based on the success of the foster care networks to provide permanency for children who are placed in out-of-home care. For the purpose of this study the foster care network organizations in each county included the child welfare agencies, the juvenile courts, private foster care agencies and foster families. The child welfare agencies in each of Ohio counties operate independently, and their success …
Genome-Wide Angiotensin Ii Regulated Microrna Expression Profiling ; A Smooth Muscle-Specific Microrna Signature, Jacqueline R. Kemp
Genome-Wide Angiotensin Ii Regulated Microrna Expression Profiling ; A Smooth Muscle-Specific Microrna Signature, Jacqueline R. Kemp
ETD Archive
Renin-angiotensin system (RAS) activation and phenotypic modulation of vascular smooth muscle cells (VSMCs) are common characteristics associated with human diseases, such as pulmonary hypertension, atherosclerosis and stroke. While elevation of the RAS hormone product, angiotensin II (AngII) is a well-established risk in these diseases the mechanism of activation of RAS and modulation of VSMC phenotype by AngII is vague, suggesting that novel global regulators may mediate the risk by AngII. MicroRNAs (miRNAs) represent one such class of potential global regulators. MiRNAs are small (╠â22 nt), endogenous, non-coding RNAs that act as post-transcriptional regulators of physiological processes. MiRNAs primarily function by …
Civilization Is Going To Pieces: Crime, Morality, And Their Role In The Great Gatsby, Kathryn F. Machcinski
Civilization Is Going To Pieces: Crime, Morality, And Their Role In The Great Gatsby, Kathryn F. Machcinski
ETD Archive
Historically the 1920s contained growing tensions among the generations, classes and races. To hear that it is turbulent is not new. This becomes part of the frame for the 1925 novel, The Great Gatsby. The other part, which this thesis treats, is that of the moral and legal crime taking place within the novel itself. Beginning with the real-life Hall-Mills murder case, the thesis enumerates and details many, often overlooked, moral and legal crimes by every character within the book. Through this is it my intention to elucidate the potentiality of F. Scott Fitzgerald to portray a culture in crisis. …
A Multi-Taxonomic Approach To Assess The Impact Of Overabundant White-Tailed Deer (Odocoileus Virginianus) In Forest Ecosystems Across Northeast Ohio, Sara A. Laux
ETD Archive
Browsing by white-tailed deer has alters plant species diversity of the forest understory across much of North America. A reduced understory may lead to the simplification of the forest-floor microhabitat, causing broad scale shifts in the community composition and abundance of litter-dwelling arthropods and small mammals. The objectives of this study were to 1) document changes in the forest-floor microhabitat as a result of over-browsing by deer and 2) determine if differential browsing pressures indirectly affect faunal biodiversity (litter-dwelling arthropods and small mammals) of forest ecosystems. I predicted that browsing within the understory will reduce structural complexity of the forest-floor …
The Role Of School And Motivational Factors In Mathematics Achievement And Self-Efficacy : A Multi-Level Analysis, Enock Obuba Meshack
The Role Of School And Motivational Factors In Mathematics Achievement And Self-Efficacy : A Multi-Level Analysis, Enock Obuba Meshack
ETD Archive
Mathematics performance in the U.S., relative to other developed countries remains unsatisfactory despite the emphasis on teacher training, rigor in teaching, and provision of physical resources, adjustments in curriculum and utilization of modern technology. Psychological aspects such as motivation and self-efficacy, which are known to have significant relationships to academic outcomes, have not been sufficiently and exhaustively studied in relation to mathematics achievement. This study used the Educational Longitudinal Survey of 2002 (ELS-2002) data available from the National Center for Educational Statistics (NCES) to explore the relationship between the students’ psychological attributes and their mathematics achievement. The ELS-2002 was a …
Design, Synthesis And Characterization Of Chain-End Functionalized Glyco-Polymer For Efficient Proteomic Analysis, Satya Nandana Narla
Design, Synthesis And Characterization Of Chain-End Functionalized Glyco-Polymer For Efficient Proteomic Analysis, Satya Nandana Narla
ETD Archive
No abstract provided.
Gradient Chromatofocusing And Reversed Phase Hplc In Protein Analysis And Lc-Ms/Ms Determination Of Thiazolidinedione Nl-1 In Mouse Serum And Brain, Kiran K. Pedada
Gradient Chromatofocusing And Reversed Phase Hplc In Protein Analysis And Lc-Ms/Ms Determination Of Thiazolidinedione Nl-1 In Mouse Serum And Brain, Kiran K. Pedada
ETD Archive
No abstract provided.
The Influence Of State-Level Renewable Energy Policy Instruments On Electricity Generation In The United States :;A Cross-Sectional Time Series Analysis, Sunjoo Park
ETD Archive
Since the late 1990s, state governments in the U.S. have diversified policy instruments for encouraging the electric power industry to deploy renewable sources for electricity generation. While observing the increasing number of new renewable energy policies at the state level governments, this study raised two research questions: (1) how do state governments intervene in the renewable energy market? and (2) how do various policy approaches taken by state governments affect renewable energy development? To answer for these questions, this study attempts to identify the trends and variations in renewable energy policy designs among states in terms of the combination of …
The Perceptions Of Principal Instructional Leadership Practices On 8th Grade Ohio Achievement Assessment (Oaa), Henry Ii Pettiegrew
The Perceptions Of Principal Instructional Leadership Practices On 8th Grade Ohio Achievement Assessment (Oaa), Henry Ii Pettiegrew
ETD Archive
The purpose of this study was to identify the instructional leadership behaviors that distinguish effective suburban school in Northeast Ohio to reach conclusions about the contextual factors that influence the nature and exercise of the instructional leadership in schools. This research was conducted for the following purposes: (a) to determine if a significant relationship between principal self-perceived instructional leadership behavior and student performance, (b) to determine if a significant relationship between teacher perceived principal instructional leadership behavior and student performance, (c) to determine the extent principals' instructional leadership behavior scores, as perceived by principals, principal experience and student socioeconomic status …
Treatment Outcomes Of The Summer Treatment Program For Children With Adhd And Comorbid Mental Health Diagnoses, Anthony Regis Pizzuti
Treatment Outcomes Of The Summer Treatment Program For Children With Adhd And Comorbid Mental Health Diagnoses, Anthony Regis Pizzuti
ETD Archive
Although there is substantial support for the efficacy of the Summer Treatment Program (Pelham, Gnagy et al., 2010) for children diagnosed with attention deficit hyperactivity disorder (ADHD), limited research has evaluated whether children diagnosed with additional mental health disorders (comorbidity) show positive outcomes and improvements when exposed to an intensive behavior program such as the Summer Treatment Program (STP). Furthermore, there is no research available that shows whether children from differing ages or gender who are diagnosed with additional mental health disorders (comorbidity) show improvements over the course of treatment. With such limited research, this study investigated a few of …
Investigations Into The Robustness Of Sustainable Real Estate Premiums And Commercial Real Estate Econometrics, Spenser J. Robinson
Investigations Into The Robustness Of Sustainable Real Estate Premiums And Commercial Real Estate Econometrics, Spenser J. Robinson
ETD Archive
This dissertation consists of three papers, all using CoStar Group, Inc. Commercial Real Estate (CRE) data. The rst two papers explore Sustainable Real Estate (Energy STAR and LEED building) rental premiums. The third paper develops and tests a new method for the empirical testing of CRE. Paper number one, Managing Well by Managing Good, is the rst paper to argue against the existence of sustainable real estate premiums. It demonstrates that some of the Sustainable Real Estate rent premiums previously shown in the literature are neither theoretically nor empirically supported. In addition to presenting theoretical arguments against the premiums, the …
A Quantitative Study Of Persistence Factors For First-Year Students At Urban And Residential Universities, Abigail Parsons Shiban
A Quantitative Study Of Persistence Factors For First-Year Students At Urban And Residential Universities, Abigail Parsons Shiban
ETD Archive
Persistence from the first to second year of college can be challenging for students at urban institutions given that they face added pressures and unique situations preventing them from persisting beyond the first year of higher education. While first-year persistence in higher education has been investigated, very little formal research exists on persistence at urban institutions. To bridge this gap, a quantitative analysis of 395 students at two urban and two residential four-year public institutions in Ohio was conducted using the Social Integration and Persistence Intentions Scale (Pascarella & Terenzini, 1980) while exploring comprehensive factors such as students' pre-college and …
Towards A Theory Of Services Supply Chain Management, John D. Smith
Towards A Theory Of Services Supply Chain Management, John D. Smith
ETD Archive
Much research has been performed to develop the supply chain management construct for manufacturing goods producing firms. However, the service sector continues to grow its dominance in the percentage of GDP in high, middle and low income countries, and with it, a corresponding growth in the percentage of purchasing spend across the globe. While research continues in the manufacturing supply chain arena, much work is yet to be done to understand the differences for services. The objectives of this research project were threefold: 1) to analyze the services supply chain management construct in order to determine how it differs from …
Effects Of Spatial Structure On Air Quality Level In U.S. Metropolitan Areas, Chang-Shik Song
Effects Of Spatial Structure On Air Quality Level In U.S. Metropolitan Areas, Chang-Shik Song
ETD Archive
The purpose of this dissertation is to investigate relationships between metropolitan spatial structure and air quality across U.S. metropolitan areas. Debates over compact city and sprawling development models as alternative patterns of metropolitan development and planning remain unsettled. This dissertation works from the hypothesis that compact regions with high-density, concentration, mixed land use, and better accessibility improve air quality. To test the compact city hypothesis, this dissertation uses a combined spatial data of population, employment, government, land use, and air quality in 610 counties in U.S. metropolitan areas and their neighboring areas for 1990, 2000, and 2006. Indicators identified widely …
Longitudinal Stability Of Effect Sizes In Educational Research, Joshua A. Stephens
Longitudinal Stability Of Effect Sizes In Educational Research, Joshua A. Stephens
ETD Archive
Effect sizes are the statistic generated by meta-analyses, a commonly used statistic in education research. Meta-analyses are widely used by education practitioners, administrators, and policy makers as a means to decide best classroom or school practices. It has been suggested by authors in other fields, most notably Jennions and Moller (2001), that effect sizes have declined over time due to various sources of bias. This paper examines the question of whether shifting effect sizes can be observed in educational research and attempts to explain possible causes of this observation. It uses the methodological framework used by Jennions and Moller (2001) …
Development Of Lc-Ms/Ms Methods For Quantitative Analysis Of Plant-Derived Anticancer Agent And Synthetic Estrogen In Complex Matrices, Simuli Lindah Wabuyele
Development Of Lc-Ms/Ms Methods For Quantitative Analysis Of Plant-Derived Anticancer Agent And Synthetic Estrogen In Complex Matrices, Simuli Lindah Wabuyele
ETD Archive
No abstract provided.