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Articles 1 - 3 of 3
Full-Text Articles in Entire DC Network
The Role Of Tbx2 In Germ Layer Suppression And Dorsoventral Patterning During Early Vertebrate Development, Shoshana Reich
The Role Of Tbx2 In Germ Layer Suppression And Dorsoventral Patterning During Early Vertebrate Development, Shoshana Reich
Dissertations, Theses, and Capstone Projects
The differentiation of the three primary germ layers is precisely regulated by inductive cues, the intracellular networks through which these signals are transduced, and a broad array of nuclear proteins, such as transcription factors and epigenetic modifiers. Precise regulation of these various factors is crucial to proper development. Members of the T-box family of DNA-binding proteins play a prominent role in the differentiation of the three primary germ layers. VegT, Brachyury, and Eomesodermin function as transcriptional activators, are expressed in the presumptive mesendoderm and, in addition to directly activating the transcription of endoderm- and mesoderm-specific genes, serve variously as regulators …
The Logic Of The Land: The Agrarian Roots Of Uneven Development In Brazil, Chris Carlson
The Logic Of The Land: The Agrarian Roots Of Uneven Development In Brazil, Chris Carlson
Dissertations, Theses, and Capstone Projects
This dissertation seeks to explain the highly uneven pattern of economic development in Brazil during the 20th century. Stark development differences between the northern and southern regions of the country have long been a problem of concern to scholars and policymakers and have generated a number of studies over the years. However, none of these have gotten to the root of the problem, and state policy has never adequately addressed the regional disparities. This study puts forth a new theory of uneven development based on the different ways that agricultural production has come to be organized in different parts …
Targeting Ampa Receptor Modulation During Early Life Adversity: A Mediator For Threat Associated Memories, Roseanna M. Zanca
Targeting Ampa Receptor Modulation During Early Life Adversity: A Mediator For Threat Associated Memories, Roseanna M. Zanca
Dissertations, Theses, and Capstone Projects
Early life adversity (ELA) is the exposure to a single or to multiple traumatic events before the age of 18 that go beyond the child’s coping. These adverse events are often exacerbated during adolescence particularly when cognitive performance is compromised. Adolescents who experienced ELA may show symptoms of post-traumatic stress disorder (PTSD), while not vividly recalling the early life trauma. These individuals show atypical connectivity between prefrontal-amygdala and hippocampus, all of which is associated with an increased risk of experiencing a traumatic event again later in life. While clinical research has increasingly stressed the importance in addressing the long-lasting consequences …