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Social Involvement, Existential Awareness, And Perceived Vulnerability In Older Adults, Maria Zarlengo
Social Involvement, Existential Awareness, And Perceived Vulnerability In Older Adults, Maria Zarlengo
Dissertations
The current study explored perceptions of old-age vulnerability by seniors as well as separate and combined effects of social involvement and existential awareness on the level of perceived vulnerability to aging. Two hundred and forty four seniors participated in the study. The data were collected with the use of a 101-question survey based on three published measures plus demographic questions. The dependent (criterion) variable was the vulnerability to old age measured by the Perceived Vulnerability Scale (PVS). The explanatory (predictor) variables included the degree of social involvement measured by the Social Provisions Scale (SPS) and the level of existential awareness …
Promoting Thymopoiesis With Age: Potential Role Of The Transcription Factor Foxn1, Erin Christine Zook
Promoting Thymopoiesis With Age: Potential Role Of The Transcription Factor Foxn1, Erin Christine Zook
Dissertations
It is known that the elderly are more susceptible to illnesses and infections and respond poorly to immunization. A contributing factor to a decrease in the immune response in the elderly is the decline in the production of naïve T cell by the thymus. In the thymus, the notch receptor expressed on early T cell progenitors (ETP) binds to its ligand expressed on thymic epithelial cells (TEC), signaling ETP to develop through a series of developmental stages before maturing into naive T cells. Because ETP are non-self renewing, the thymus relies on the bone marrow (BM) for a continuous supply …