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Department of Food Science and Technology: Dissertations, Theses, and Student Research

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2016

Killer toxin

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Studies Of Debaryomyces Hansenii Killer Toxin And Its Effect On Pathogenic Bloodstream Candida Isolates, Rhaisa A. Crespo Ramírez Apr 2016

Studies Of Debaryomyces Hansenii Killer Toxin And Its Effect On Pathogenic Bloodstream Candida Isolates, Rhaisa A. Crespo Ramírez

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Candida species are normal commensal organisms found in the skin, mouth, and gastrointestinal and genitourinary tracts of humans. Candida albicans is a normal component of the gut flora, and the oral and genital cavities. However, this organism is an opportunistic pathogen and it is one of the most frequently isolated species from patients with nosocomial fungal infections. Candida infections have grown in recent years due to antimycotics resistance and the extensive use of antibiotics. This has pushed scientists to look for alternative therapeutic agents to treat fungal infections.

Yeasts can produce toxic proteins called “mycocins” or “killer toxins” that can …