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Computer Science Theses & Dissertations

Theses/Dissertations

2014

Machine learning

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Improving Structural Features Prediction In Protein Structure Modeling, Ashraf Yaseen Jul 2014

Improving Structural Features Prediction In Protein Structure Modeling, Ashraf Yaseen

Computer Science Theses & Dissertations

Proteins play a vital role in the biological activities of all living species. In nature, a protein folds into a specific and energetically favorable three-dimensional structure which is critical to its biological function. Hence, there has been a great effort by researchers in both experimentally determining and computationally predicting the structures of proteins.

The current experimental methods of protein structure determination are complicated, time-consuming, and expensive. On the other hand, the sequencing of proteins is fast, simple, and relatively less expensive. Thus, the gap between the number of known sequences and the determined structures is growing, and is expected to …


Document Classification In Support Of Automated Metadata Extraction Form Heterogeneous Collections, Paul K. Flynn Apr 2014

Document Classification In Support Of Automated Metadata Extraction Form Heterogeneous Collections, Paul K. Flynn

Computer Science Theses & Dissertations

A number of federal agencies, universities, laboratories, and companies are placing their documents online and making them searchable via metadata fields such as author, title, and publishing organization. To enable this, every document in the collection must be catalogued using the metadata fields. Though time consuming, the task of identifying metadata fields by inspecting the document is easy for a human. The visual cues in the formatting of the document along with accumulated knowledge and intelligence make it easy for a human to identify various metadata fields. Even with the best possible automated procedures, numerous sources of error exist, including …