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Evaluation Of Aspartate Aminotransferase To Platelet Ratio Index And Fibrosis 4 Score For Selecting Patients With Chronic Hepatitis B To Perform Liver Fibrosis Assessment By Transient Elastography In Resource-Limited Areas, Puth Muangpaisarn
Chulalongkorn Medical Journal
Background: Liver stiffness measurement operated by transient elastography (TE) becomes a noninvasive method to assess the severity of hepatic fibrosis. However, TE may not be available in resource-limiting areas. Therefore, simple serum biomarker scoring should be evaluated for fibrotic assessment instead of TE.
Objectives: This study aimed to evaluate the diagnostic performance of aspartate. aminotransferase to platelet ratio index (APRI) and fibrosis-4 (FIB-4) scores compared with TE in chronic hepatitis B (CHB) patients and determine the optimal cut-off values to select the CHB patients who should be referred to higher-level hospital for TE evaluation.
Methods: We conducted a cross-sectional study …