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Theses/Dissertations

2011

Stress

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Kids Able To Fight Stress Everyday (Kafse): A Stress-Management Program For Children With Medical Diagnoses, Aimee N. Townsend Jan 2011

Kids Able To Fight Stress Everyday (Kafse): A Stress-Management Program For Children With Medical Diagnoses, Aimee N. Townsend

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It is estimated that 10-30% of children in the United States are currently diagnosed with a chronic illness. Due to recent medical advances and increased knowledge of disease maintenance, many of these children will live into adulthood. In addition to physical symptoms of chronic illness, recent attention has been drawn to the psychological effects of chronic illness on children and adolescents. Illustrating this fact, researchers have recently called for increased research on children with chronic illness and disease. One psychological symptom that may be considered is that of stress and its effects on this special population. As a result of …


Low Dose Nerve Agent Sarin Causes Dilated Cardiomyopathy And Autonomic Imbalance In Mice, Swapnil Vijay Shewale Jan 2011

Low Dose Nerve Agent Sarin Causes Dilated Cardiomyopathy And Autonomic Imbalance In Mice, Swapnil Vijay Shewale

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Sarin, a lethal chemical nerve agent, may be a causative factor in multifactorial syndrome implicated in the Gulf War and Tokyo terrorist attacks. While high dose results in seizure and death, low dose exposure may lead to autonomic imbalance and chronic cardiac pathologies. In the present study, echocardiography and electrocardiography were used to examine the late onset effects of a low dose sarin on cardiac structure and function in mice. Stress responsiveness of the hypothalamic pituitary adrenal (HPA) axis was also tested. Findings demonstrate changes consistent with a dilated cardiomyopathy, including left ventricular dilatation, reduced contractility, and altered electrophysiological and …