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Flight Muscle Progenitor Populations In Drosophila Melanogaster, Elizabeth Clarke

Biology ETDs

We use the Drosophila system to define how genes control muscle development and function. Many of the genes in the fruit fly, Drosophila melanogaster, are conserved with higher animals, and so our results can be important in understanding mechanisms of vertebrate muscle development and disease. Study of the flight muscle progenitor populations in Drosophila gives clearer understanding of the genetic regulatory networks that lead to the development of flight muscle. The direct flight muscles (DFMs) and indirect flight muscles (IFMs) arise from the myoblast population of the notal region of the Drosophila wing imaginal disc. Within the myoblast population, there …