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All ETDs from UAB

Theses/Dissertations

2014

Master of Science in Public Health (MSPH) School of Public Health

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Interaction Between A Low-Iron Diet And Early-Life Methylmercury Exposure In Daphnia Pulex, Sherri Hudson Jan 2014

Interaction Between A Low-Iron Diet And Early-Life Methylmercury Exposure In Daphnia Pulex, Sherri Hudson

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Methylmercury (MeHg) is a known neurotoxicant and bioaccumulates in fish, with exposure to humans in utero being of highest concern. Iron deficiency (ID) accounts for approximately 50% of anemia cases. Anemia is estimated to affect 1.62 billion people worldwide, and is particularly problematic during pregnancy and early life. Previous studies have shown that ID exacerbates toxicity associated with exposure to metals, including lead, manganese, and cadmium. The overall purpose of this thesis research is to investigate the interaction between a low-iron (Fe) diet and early-life exposure to MeHg in Daphnia pulex. I hypothesized when D. pulex are fed a low-Fe …


Combinatorial Effects Of Corexit 9500a And Temperature Stressors On Embryo Development In The Zebrafish Danio Rerio, Erica Davis Anderson Jan 2014

Combinatorial Effects Of Corexit 9500a And Temperature Stressors On Embryo Development In The Zebrafish Danio Rerio, Erica Davis Anderson

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To reduce possible ecological impact from oil spill events, the chemical dispersant Corexit 9500A is approved for widespread application. Concerns about toxic effects of dispersant on aquatic fauna have prompted numerous recent toxicological studies. Few of these studies have considered possible interactive effects involving Corexit exposure at normative or high temperatures associated with normal breeding seasons of many aquatic organisms. We examined development, survival, and hatch success of teleost model Danio rerio embryos exposed to Corexit while maintained at various temperatures. Calculated LC25, 50, and 75 values at 24 h Corexit exposure for 3 hpf embryos reared at the standard …


Effects Of Early Life Exposure To Methylmercury On Predator Response In Daphnia Pulex, Megan Lisa Steed Jan 2014

Effects Of Early Life Exposure To Methylmercury On Predator Response In Daphnia Pulex, Megan Lisa Steed

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Knowledge of the health effects of toxic chemicals is largely based on single chemical models rather than a multi-factor model, which more accurately captures realworld exposures. This study investigated how methylmercury affects Daphnia pulex in the presence of predatory stress chemical. A kairomone is an infochemical released by an animal that can be detected by another animal. Daphnia pulex detects kairomone released by Danio rerio resulting in the induction of morphological and life history changes. Danio rerio were kept in COMBO media for 24 hours at a density of 2 fish per liter. Daphnids were then housed in kairomone-containing COMBO …