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Abington Jefferson Health Papers

2022

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Psychosis-Induced Exertional Rhabdomyolysis Without Acute Kidney Injury Or Myoglobinuria., Joann M Butkus, Mackenzie Kramer, Vincent Chan, Eunha Kim Jan 2022

Psychosis-Induced Exertional Rhabdomyolysis Without Acute Kidney Injury Or Myoglobinuria., Joann M Butkus, Mackenzie Kramer, Vincent Chan, Eunha Kim

Abington Jefferson Health Papers

BACKGROUND Rhabdomyolysis is a clinical syndrome that results from skeletal muscle breakdown and the release of intracellular enzymes into systemic circulation [1,2]. We present a case of non-traumatic rhabdomyolysis with transaminitis, without myoglobinuria or acute kidney injury. Cases reports of rhabdomyolysis with elevation of serum creatine kinase (hyperCKemia) in the absence of myoglobinuria or renal failure are limited in the literature.

CASE REPORT A 21-year-old man presented to the Emergency Department following an acute psychotic episode. One week earlier, his bloodwork had been within normal limits. Biochemical investigations on admission revealed hyperCKemia (590 000 U/L), transaminitis (AST, 628; ALT, 160), …