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Neonatal Abstinence Syndrome: A Retrospective Review Of Clonidine As An Adjunct To Opioid Treatment, Joanna Schatz
Neonatal Abstinence Syndrome: A Retrospective Review Of Clonidine As An Adjunct To Opioid Treatment, Joanna Schatz
Yale Medicine Thesis Digital Library
NEONATAL ABSTINENCE SYNDROME: A RETROSPECTIVE REVIEW OF CLONIDINE AS AN ADJUNCT TO OPIOD TREATMENT. Joanna J. Schatz (Sponsored by Matthew R. Grossman). Department of Pediatrics, Yale University, School of Medicine, New Haven, CT. This was a retrospective medical record review of treatment for neonatal abstinence syndrome (NAS) due to in utero exposure to opioids. The purpose of our study was to determine if there was a difference in the duration of treatment between infants who received morphine alone compared to infants who were treated with both morphine and clonidine. We hypothesized that there would be a decrease in the duration …
Ultrasound Measurement Of The Inferior Vena Cava Diameter In The Assessment Of Pediatric Dehydration, Yunie Kim
Ultrasound Measurement Of The Inferior Vena Cava Diameter In The Assessment Of Pediatric Dehydration, Yunie Kim
Yale Medicine Thesis Digital Library
Dehydration is a common pediatric condition, but limitations exist with current methods of assessing pediatric fluid status, particularly with interobserver variabilities in clinical assessment and the inaccuracy and questionable validity of laboratory tests. Bedside ultrasonography (US) measurement of the inferior vena cava (IVC) and aorta (Ao) may be useful in objectively assessing children with suspected dehydration. The objectives of this study were 1) to compare the IVC and Ao diameter (IVC/Ao) ratio of dehydrated children with euvolemic controls and 2) to compare the IVC/Ao ratio before and after intravenous (IV) rehydration in children with clinical dehydration. This prospective observational study …
The Infant And Effects Of Parental Presence In The Operating Room During Induction Of Anesthesia, Deborah Kaplan
The Infant And Effects Of Parental Presence In The Operating Room During Induction Of Anesthesia, Deborah Kaplan
Yale Medicine Thesis Digital Library
Previous studies have investigated the physiological and behavioral effects of parental presence in the operating room during the induction of anesthesia (PPIA) both on the child and the parent. Since the characterization of anxiety in infants presents a unique challenge due to their inability to communicate verbally, these studies have typically focused on children greater than two years old. In the present study we addressed this understudied population directly by using highly reliable and validated behavioral instruments as well as analyzing sleep patterns and signs of distress in the infants. The hypothesis tested was the same as in the older …
Serum S-100b As A Potential Biomarker For Meningitis In Febrile Infants: An Interim Analysis, Kelvin C. Lau
Serum S-100b As A Potential Biomarker For Meningitis In Febrile Infants: An Interim Analysis, Kelvin C. Lau
Yale Medicine Thesis Digital Library
The purpose of this study is to identify the utility of serum S-100B levels as a marker for meningitis in febrile infants younger than 3 months of age. All infants younger than 3 months of age who presented to the Pediatric Emergency Department (PED) of Yale-New Haven Children's Hospital and required both a lumbar puncture and venipuncture due to either a confirmed rectal temperature ≥38.0°C or an overall presentation that concerned the responsible physician for possible meningitis and required a lumbar puncture as part of their PED evaluation, were prospectively enrolled. A total of 111 patients participated after a 1.5-year …
Methicillin-Susceptible Staphylococcus Aureus Colonization In The Neonatal Intensive Care Unit, Shoaib Syed Ahmed
Methicillin-Susceptible Staphylococcus Aureus Colonization In The Neonatal Intensive Care Unit, Shoaib Syed Ahmed
Yale Medicine Thesis Digital Library
Introduction: Nasal carriage of Staphylococcus aureus is a sensitive indicator of staphylococcal colonization and is considered a source of subsequent infection. When the incidence of Staphylococcus aureus colonization increased in our neonatal intensive care unit (NICU), resulting in 3 methicillin-resistant Staphylococcus aureus (MRSA) infections over a 3 month period, we sought to further our understanding of S. aureus epidemiology and response to infection control practice. The purpose of this investigation was to study the methicillin-susceptible Staphylococcus aureus (MSSA), and further determine the clonal spread of MSSA strain types. Since few studies have analyzed the clinical profile of MSSA in neonates, …