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Yale University

2006

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Bear Stearns High Grade Structured Credit Strategies Enhanced Leverage Master Fund Financial Statements, Bear Stearns Companies, Inc. Dec 2006

Bear Stearns High Grade Structured Credit Strategies Enhanced Leverage Master Fund Financial Statements, Bear Stearns Companies, Inc.

Documents

No abstract provided.


Nigerian Deposit Insurance Act, National Assembly Dec 2006

Nigerian Deposit Insurance Act, National Assembly

Documents

Act replacing the NDIC Act of 1988, which established the NDIC.


Goldman Sachs Internal Email Re Mezz Risk 1, Psi Exhibit 151, David A. Lehman, Stacy Bash-Polley Dec 2006

Goldman Sachs Internal Email Re Mezz Risk 1, Psi Exhibit 151, David A. Lehman, Stacy Bash-Polley

Documents

No abstract provided.


Nomura Fixed Income Research, Cdo Cds Update, Nomura Holdings Dec 2006

Nomura Fixed Income Research, Cdo Cds Update, Nomura Holdings

Documents

No abstract provided.


Goldman Sachs Email From David Viniar To Tom Montag Regarding Subprime Risk Meeting With Viniar Mcmahon, David Viniar, Tom Montag, Daniel Sparks Dec 2006

Goldman Sachs Email From David Viniar To Tom Montag Regarding Subprime Risk Meeting With Viniar Mcmahon, David Viniar, Tom Montag, Daniel Sparks

Documents

No abstract provided.


Official Gazette Of The Republic Of Slovenia, Slovenia: Official Gazette (Uradni List Republike Slovenije) Dec 2006

Official Gazette Of The Republic Of Slovenia, Slovenia: Official Gazette (Uradni List Republike Slovenije)

Documents

No abstract provided.


Kevin Gasvoda Email To Genevieve Nestor And Others Re Retained Bonds, Psi Exhibit 72, Kevin S. Gasvoda Dec 2006

Kevin Gasvoda Email To Genevieve Nestor And Others Re Retained Bonds, Psi Exhibit 72, Kevin S. Gasvoda

Documents

No abstract provided.


Guideline Of The European Central Bank Of 31 August 2006 Amending Guideline Ecb/2000/7 On Monetary Policy Instruments And Procedures Of The Eurosystem, European Central Bank (Ecb) Dec 2006

Guideline Of The European Central Bank Of 31 August 2006 Amending Guideline Ecb/2000/7 On Monetary Policy Instruments And Procedures Of The Eurosystem, European Central Bank (Ecb)

Documents

ECB's pre-crisis policies and a general primer on how the Eurosystem functions


Michael Dinias Email To David Viniar And Craig Broderick, Senate Psi Exhibit 2, David Viniar, Michael Dinias Dec 2006

Michael Dinias Email To David Viniar And Craig Broderick, Senate Psi Exhibit 2, David Viniar, Michael Dinias

Documents

No abstract provided.


The Effects Of Benzo-Α-Pyrene On The Insulin-Like Growth Factor-I Gene, Brittany Albright Epperson Dec 2006

The Effects Of Benzo-Α-Pyrene On The Insulin-Like Growth Factor-I Gene, Brittany Albright Epperson

Yale Medicine Thesis Digital Library

The purpose of this study was to look at the genotoxic and cytotoxic effects of benzo-α-pyrene (BαP), a chemical mutagen that is present in cigarette smoke, on the insulin-like growth factor-I (IGF-I) gene. Women who smoke during pregnancy are more likely to have a growth-restricted baby. We hypothesized that BαP exerts its effects through genotoxic and cytotoxic avenues. The cytotoxicity is manifested by chromosomal abnormalities and a decrease in the rate of cell division. The genotoxicity is manifested by changes in certain genes known to be important in mammalian fetal development such as IGF-I. IGF-I is implicated in intrauterine growth …


Fortius Ii Funding Cdo Offering Circular, Goldman Sachs Dec 2006

Fortius Ii Funding Cdo Offering Circular, Goldman Sachs

Documents

This offering circular serves the interest of Fortius II Funding and Goldman Sachs.


Sec Risk Management Review Of Consolidated Supervised Entities (December 5, 2006), United States: Securities And Exchange Commission: Office Of Prudential Supervision And Risk Analysis (Opsra) Dec 2006

Sec Risk Management Review Of Consolidated Supervised Entities (December 5, 2006), United States: Securities And Exchange Commission: Office Of Prudential Supervision And Risk Analysis (Opsra)

Documents

No abstract provided.


Hudson Mezzanine Funding 2006-1 Cdo Offering Circular, Goldman Sachs Dec 2006

Hudson Mezzanine Funding 2006-1 Cdo Offering Circular, Goldman Sachs

Documents

This offering circular serves the interest of Hudson Mezzanine Funding and Goldman Sachs.


Female Empowerment: Impact Of A Commitment Savings Product In The Philippines, Nava Ashraf, Dean Karlan, Wesley Yin Dec 2006

Female Empowerment: Impact Of A Commitment Savings Product In The Philippines, Nava Ashraf, Dean Karlan, Wesley Yin

Discussion Papers

No abstract provided.


Asymptotic Theory For Local Time Density Estimation And Nonparametric Cointegrating Regression, Qiying Wang, Peter C.B. Phillips Dec 2006

Asymptotic Theory For Local Time Density Estimation And Nonparametric Cointegrating Regression, Qiying Wang, Peter C.B. Phillips

Cowles Foundation Discussion Papers

We provide a new asymptotic theory for local time density estimation for a general class of functionals of integrated time series. This result provides a convenient basis for developing an asymptotic theory for nonparametric cointegrating regression and autoregression. Our treatment directly involves the density function of the processes under consideration and avoids Fourier integral representations and Markov process theory which have been used in earlier research on this type of problem. The approach provides results of wide applicability to important practical cases and involves rather simple derivations that should make the limit theory more accessible and useable in econometric applications. …


Auriga Cdo Offering Circular, Merrill Lynch International Dec 2006

Auriga Cdo Offering Circular, Merrill Lynch International

Documents

This offering circular serves the interest of Auriga and Merrill Lynch.


Goldman Viniar, Montag, Sparks, Ruzika Email Chain Re Subprime Risk Meeting, Psi Exhibit 3, David Viniar, Tom Montag, Daniel Sparks Dec 2006

Goldman Viniar, Montag, Sparks, Ruzika Email Chain Re Subprime Risk Meeting, Psi Exhibit 3, David Viniar, Tom Montag, Daniel Sparks

Documents

No abstract provided.


Goldman Fabrice Tourre Email To Jonathan Egol, Psi Exhibit 61, Fabrice Tourre, Jonathan Egol Dec 2006

Goldman Fabrice Tourre Email To Jonathan Egol, Psi Exhibit 61, Fabrice Tourre, Jonathan Egol

Documents

No abstract provided.


Center For Responsible Lending, Losing Ground Foreclosures In The Subprime Market And Their Cost To Homeowners, Ellen Schloemer, Wei Li, Keith Ernst, Kathleen Keest Dec 2006

Center For Responsible Lending, Losing Ground Foreclosures In The Subprime Market And Their Cost To Homeowners, Ellen Schloemer, Wei Li, Keith Ernst, Kathleen Keest

Documents

No abstract provided.


Bear Stearns Matt Tannin Email Diary Entry, Matthew Tannin Nov 2006

Bear Stearns Matt Tannin Email Diary Entry, Matthew Tannin

Documents

No abstract provided.


Memo Re: Occ Letter From Scott N Waterhouse To Bruce W Johnson Re Recommendation For Removal Of Formal Agreement, Bruce W. Johnson Nov 2006

Memo Re: Occ Letter From Scott N Waterhouse To Bruce W Johnson Re Recommendation For Removal Of Formal Agreement, Bruce W. Johnson

Documents

No abstract provided.


Wilmarth - Conflicts Of Interest And Corporate Governance Failures At Universal Banks During The Stock Market Boom Of The 1990s: The Cases Of Enron And Worldcom, Art Wilmarth Nov 2006

Wilmarth - Conflicts Of Interest And Corporate Governance Failures At Universal Banks During The Stock Market Boom Of The 1990s: The Cases Of Enron And Worldcom, Art Wilmarth

Documents

No abstract provided.


Kleros Real Estate Iii Cdo Offering Circular, Ubs Investment Bank Nov 2006

Kleros Real Estate Iii Cdo Offering Circular, Ubs Investment Bank

Documents

This offering circular serves the interest of Kleros Real Estate CDO III and UBS Investment Bank.


The Impact Of High Density Lipoprotein Cholesterol On Five-Year Mortality In Older Adults, Lisa Millman Nov 2006

The Impact Of High Density Lipoprotein Cholesterol On Five-Year Mortality In Older Adults, Lisa Millman

Yale Medicine Thesis Digital Library

The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) guidelines have defined a high density lipoprotein cholesterol (HDL-C) of <50 mg/dL in women and <40 mg/dL in men as a risk factor for cardiovascular disease. Our research aim was to examine the relationship between untreated HDL-C levels below this recommended level on five year cardiovascular, stroke, and all-cause mortality in adults over 71 years of age. The Established Populations for Epidemiologic Studies of the Elderly (EPESE) is a prospective cohort study of community dwelling adults over 65 years of age in East Boston, MA; Iowa and Washington Counties, IA; New Haven, CT; and Durham, NC. The National Institutes of Aging (NIA) started EPESE to study health, social, psychological, and economic aspects of older adults lives through extensive annual interviews. The EPESE dataset is further enriched by serum measures including low-density lipoprotein cholesterol (LDL-C), HDL-C, total cholesterol, triglycerides, glucose, BUN and creatinine, which were obtained at the sixth annual follow-up interview. Our primary outcome was all-cause mortality with secondary mortality outcomes of acute myocardial infarction (AMI), coronary artery disease (CAD) not AMI, and congestive heart failure (CHF). The mean age of our cohort was 78.7 years with the majority being female (63.86%), white (88.15%), and married (52.80%). Just over half (52.07%) of our cohort met the criteria for low HDL-C as defined by ATP III. Chi square and Fisher exact test were used to compare demographics (age, gender, race, marital status, education), clinical variables (history of MI, cancer, diabetes, angina, smoking, alcohol use), and functional variables (activities of daily living, gross mobility, cognitive status) at baseline and five year follow-up. Cox proportional hazard models were created using a step-wise approach to assess the impact of low HDL-C on mortality. Low HDL-C was not significantly associated with crude all-cause (P= .413), AMI (P= .473), CHF (P= .259), and stroke (P= .345) mortality. HDL-C was significantly associated with unadjusted CAD (P= .033) mortality. However, after adjustment for demographics, clinical, and functional variables as well as the other blood values all outlined above, HDL-C was not associated with five year all-cause, AMI, CAD, CHF or stroke mortality with adjusted hazard ratios of (HR=1.03, 95% CI 0.90-1.18), (HR=1.09, 95% CI 0.70-1.71), (HR=1.33, 95% CI 0.91-1.92), (HR=1.07, 95% CI 0.63-1.81) and (HR=0.80, 95% CI 0.51-1.27) respectively. In older community dwelling adults enrolled in EPESE, low HDL-C levels as stratified by current recommended guidelines (<50 mg/dL in women and <40 mg/dL in men) were not associated with increased risk of five-year cardiovascular, stroke or all-cause mortality. HDL-C alone may have minimal effect on future longevity in older adults due to competing risk and co-morbid conditions. Further studies are required to determine whether the movement toward more aggressive lipid profile interventions specifically to raise HDL-C in older adults would prove beneficial in this growing segment of our population.


The Prevalence Of Undiagnosed Hypertension In Ambulatory Emergency Department Patients And Lack Of Adequate Referral, Andrew Nerlinger Nov 2006

The Prevalence Of Undiagnosed Hypertension In Ambulatory Emergency Department Patients And Lack Of Adequate Referral, Andrew Nerlinger

Yale Medicine Thesis Digital Library

OBJECTIVES: According to a WHO estimate, 1 in every 8 deaths worldwide is due to high blood pressure (BP). The Emergency Department (ED) provides an opportunity to identify individuals with undiagnosed hypertension (HTN) and refer them for BP recheck. The study objectives were to quantify the population in need referral for BP recheck and to determine the frequency of referral from the ED. METHODS: A retrospective, structured chart review of all patients > 18 years old seen in an urban adult ED over 5 days, excluding major trauma and pregnant pts. Patients with any systolic BP (SBP) > 140 or diastolic BP …


Effect Of Soy Isoflavone Protein And Soy Lecithin On Endothelial Function In Healthy Postmenopausal Women, Mary Pearson Nov 2006

Effect Of Soy Isoflavone Protein And Soy Lecithin On Endothelial Function In Healthy Postmenopausal Women, Mary Pearson

Yale Medicine Thesis Digital Library

The purpose of this study was to assess the effects of soy isoflavone protein concentrate and soy lecithin on endothelial function measured as flow mediated dilation (FMD) of the brachial artery in healthy postmenopausal women. In this randomized, double-blind, placebo controlled crossover trial, twenty-five subjects (mean age 61 years; BMI 25.46 kg/m2) were recruited from the general population of southwestern Connecticut. Subjects underwent endothelial function testing using high frequency ultrasound at baseline and following 4 weeks of each randomly assigned treatment with intervening 4-week washout periods. Treatment assignment included: soy isoflavone protein (SP, 25gm/day) or soy lecithin (SL, 20gm/day) alone …


Uterine Arterial Embolization: Classification Of Leiomyomas To Determine Predictors Of Response, Trusher Patel Nov 2006

Uterine Arterial Embolization: Classification Of Leiomyomas To Determine Predictors Of Response, Trusher Patel

Yale Medicine Thesis Digital Library

The purpose of this study is to determine features of uterine leiomyoma on Magnetic Resonance Imaging (MRI) that identify predictors of response to Uterine Arterial Embolization (UAE). MRI images were obtained before and after UAE in 35 women. These images were analyzed for uterine and fibroid size changes along with fibroid border characteristics and location for a total of 73 fibroids. Fibroids were classified as either smooth or lobulated based on border appearance on MR imaging to determine any differences in mean fibroid volume reduction post-embolization. The mean decrease in fibroid volume from pre-embolization to post-embolization was 48.1% ± 28.6 …


Upregulation Of Hypoxia-Inducible Genes In Endothelial Cells To Create Artificial Vasculature, Robert Schonberger Nov 2006

Upregulation Of Hypoxia-Inducible Genes In Endothelial Cells To Create Artificial Vasculature, Robert Schonberger

Yale Medicine Thesis Digital Library

This study explored the possibility that upregulation of Hypoxia Inducible Factor-1 (Hif-1)-responsive genes in Human Umbilical Vein Endothelial Cells (HUVEC) would promote and stabilize HUVEC formation into inchoate vascular beds within artificial collagen gels. This experiment was designed to explore the above possibility by sub-cloning Hif-1α, the related chimeric construct Hif-1α/VP16, and the marker gene dsRed into retroviral expression vectors, producing retroviral vectors containing these genes, and stably transducing HUVEC using these retroviruses. Transduced HUVEC were to be observed in cell culture as well as after implantation into artificial collagen gels that have previously supported vascular bed formation by HUVEC. …


Routine Anal Cytology Screening For Anal Squamous Intraepithelial Lesions In An Ethnically Diverse Urban Hiv Clinic, Hyman Scott Nov 2006

Routine Anal Cytology Screening For Anal Squamous Intraepithelial Lesions In An Ethnically Diverse Urban Hiv Clinic, Hyman Scott

Yale Medicine Thesis Digital Library

Anal cancer, like cervical cancer, is associated with Human Papillomavirus (HPV) infection. HIV+ patients have 38-60 fold increased risk of anal cancer compared to HIV- patients prompting many to suggest routine screening given the success of cervical Pap screening. Our goal is to describe our experience with routine anal Pap screening, determine which patients are most likely to have abnormal results, if anal disease on physical exam is predictive of cytology, and correlate cytology with histology findings. Charts of all patients with an anal Pap followed at the Hospital of Saint Raphael HIV Clinic were reviewed. Demographics, immune status, sexually …


Effect Of Counterface Roughness On The Cross-Path Wear Of Ultra-High Molecular Weight Polyethylene, Mary Turell Nov 2006

Effect Of Counterface Roughness On The Cross-Path Wear Of Ultra-High Molecular Weight Polyethylene, Mary Turell

Yale Medicine Thesis Digital Library

Ultra-high molecular weight polyethylene (UHMWPE) is used worldwide as a bearing material in total joint replacement prostheses. Despite its excellent biocompatibility and high wear resistance, wear of UHMWPE components continues to be a major problem limiting the clinical lifespan of UHMWPE-containing orthopaedic implant devices. Multi-directional motion or cross-path motion is known to affect wear rates of UHMWPE in total knee and hip replacement prostheses. The purpose of this study was to quantify the effect of counterface roughness on the cross-path wear of UHMWPE and to determine if the previously established unified theory of wear model could accurately predict wear rates …