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Transforming Possible Risk Into Certain Harm: A Critical Interpretive Synthesis Of The Literature On Perinatal Cannabis Use, Rachael Pack, Grace Hilton, Facundo Garcia-Bournissen, Taryn Taylor
Transforming Possible Risk Into Certain Harm: A Critical Interpretive Synthesis Of The Literature On Perinatal Cannabis Use, Rachael Pack, Grace Hilton, Facundo Garcia-Bournissen, Taryn Taylor
Obstetrics & Gynaecology Publications
Substance use in pregnancy has been a prominent public health concern for the last several decades. Since the legalization of cannabis in Canada and across several American states, cannabis use during pregnancy has gained considerable public health, scientific, and media attention. This critical interpretive synthesis explores how the problem of cannabis use in pregnancy is constructed in the scientific literature and illuminates clinical, social, and political responses this construction engenders. The state of empirical evidence regarding the impact of perinatal cannabis use is fraught; a number of studies, of variable quality, have found no associations between cannabis use and adverse …
Lockdown, Bottoms Up? Changes In Adolescent Substance Use Across The Covid-19 Pandemic, Tara M. Dumas, Wendy E. Ellis, Stephen Van Hedger, Dana M. Litt, Madeleine Macdonald
Lockdown, Bottoms Up? Changes In Adolescent Substance Use Across The Covid-19 Pandemic, Tara M. Dumas, Wendy E. Ellis, Stephen Van Hedger, Dana M. Litt, Madeleine Macdonald
Neuroscience Institute Publications
The COVID-19 pandemic notably altered adolescent substance use during the initial stage (Spring 2020) of the pandemic. The purpose of this longitudinal study is to examine trajectories of adolescent substance use across the pandemic and subsequent periods of stay-at-home orders and re-opening efforts. We further examined differences as a function of current high school student versus graduate status. Adolescents (n = 1068, 14–18 years, Mage = 16.95 years and 76.7% female at T1) completed 4 different self-report surveys, starting during the first stay-at-home order and ending approximately 14 months later. Negative binomial hurdle models predicted: (1) the likelihood of no …
Prenatal Exposure To Delta-9-Tetrahydrocannabinol (Thc) Alters The Expression Of Mir-122-5p And Its Target Igf1r In The Adult Rat Ovary, Annia A. Martínez-Peña, Kendrick Lee, Madison Pereira, Ahmed Ayyash, James J. Petrik, Daniel B. Hardy, Alison C. Holloway
Prenatal Exposure To Delta-9-Tetrahydrocannabinol (Thc) Alters The Expression Of Mir-122-5p And Its Target Igf1r In The Adult Rat Ovary, Annia A. Martínez-Peña, Kendrick Lee, Madison Pereira, Ahmed Ayyash, James J. Petrik, Daniel B. Hardy, Alison C. Holloway
Obstetrics & Gynaecology Publications
As cannabis use during pregnancy increases, it is important to understand its effects on the developing fetus. Particularly, the long-term effects of its psychoactive component, delta-9-tetrahydrocannabinol (THC), on the offspring’s reproductive health are not fully understood. This study examined the impact of gestational THC exposure on the miRNA profile in adult rat ovaries and the possible consequences on ovarian health. Prenatal THC exposure resulted in the differential expression of 12 out of 420 evaluated miRNAs. From the differentially expressed miRNAs, miR-122-5p, which is highly conserved among species, was the only upregulated target and had the greatest fold change. The upregulation …
Exploring Parent And Peer Support As A Predictor Of Adolescent Adjustment During The Covid-19 Pandemic, Madeleine M. Macdonald
Exploring Parent And Peer Support As A Predictor Of Adolescent Adjustment During The Covid-19 Pandemic, Madeleine M. Macdonald
Undergraduate Honours Theses
Research has demonstrated that adolescents’ social relationships have been negatively impacted by the COVID-19 pandemic (Ayers et al., 2021). Considering adolescence is characterized by a need for peer belonging and autonomy from parents, isolation from peers has been particularly challenging (Magson et al., 2021). Prior literature has noted the ability of parent connectedness to promote resiliency and instill self-care practices (Bender & Ingram, 2018), and for peers to provide additional necessary support and feelings of belongingness (Brown & Larson, 2009). Information on whether the same outcomes can result during the pandemic remains unknown. The purpose of this study is to …