Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Biological and Chemical Physics (1)
- Cancer Biology (1)
- Cell and Developmental Biology (1)
- Computer Sciences (1)
- Diseases (1)
-
- Endocrine System Diseases (1)
- Life Sciences (1)
- Medical Biochemistry (1)
- Medical Molecular Biology (1)
- Medical Physiology (1)
- Medical Sciences (1)
- Medicine and Health Sciences (1)
- Numerical Analysis and Scientific Computing (1)
- Nutritional and Metabolic Diseases (1)
- Physical Sciences and Mathematics (1)
- Physics (1)
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
The Effects Of Estrogen In The Glucoregulatory Response To Exercise In Type 1 Diabetes, Mitchell James Sammut
The Effects Of Estrogen In The Glucoregulatory Response To Exercise In Type 1 Diabetes, Mitchell James Sammut
Undergraduate Student Research Internships Conference
Regular exercise has shown to benefit the health of individuals with type 1 diabetes mellitus (T1DM). However, a barrier to regular exercise for this population is the fear of low blood glucose (BG) levels, also known as hypoglycemia. Hypoglycemia can result in short and long-term side-effects, such as recurring loss of consciousness or in severe cases death.
In non-diabetics, sex-related differences in fuel selection during exercise are well established. Women shift towards using fats as fuel whereas men rely mostly on sugars (i.e., carbohydrates) for energy production. Exercise during the luteal phase of the female menstrual cycle, where estrogen levels …
Numerical Simulation Of Adaptive Metabolic Response To Anti-Angiogenic Treatment In Renal Cell Carcinoma, Saranya Varakunan
Numerical Simulation Of Adaptive Metabolic Response To Anti-Angiogenic Treatment In Renal Cell Carcinoma, Saranya Varakunan
Undergraduate Student Research Internships Conference
Renal cell carcinoma, a malignant kidney cancer, is often treated using anti-angiogenic drugs to prevent the growth of blood vessels within the tumour. Although tumours initially respond to this treatment, they eventually develop resistance. This resistance is hypothesized to be caused by a switch to a symbiotic metabolism that allows cells to survive even with a low blood supply.
This project seeks to computationally model the transport of oxygen, lactate, and glucose within a tumour in order to examine how cancer metabolism adapts to changes in blood vessels.