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The Effects Of A Sympathiomimetric Stressor On The Protestant Ethic Effect In Rats, Peter Mirabelle

Masters Theses & Specialist Projects

In an experiment which investigated the effects of stress on the Protestant Ethic Effect (PEE) 12 Wistar rats were trained for 20 days to barpress for their total water intake. Following training the rats were divided into two groups and were allowed to choose between barpressing for a 10% sucrose solution and consuming a freely available sucrose solution under either stress or nonstress conditions. Stress was defined as a .01 cc per 36g body weight injection of norepinephrine. The stress and nonstress conditions were counterbalanced during the choice session. Regardless of stress order both groups preferred the free over the …

Radioprotection Of Oral Cavity Structures By S-2-(3-Aminopropylamino) Ethyl Phosphorothioate (Wr-2721), Ronald King

Masters Theses & Specialist Projects

Studies reporting a high concentration of WR-2721 in mouse salivary glands led to our studies of possible radioprotection of these glands by this drug from ionizing radiation. Oral effects of radiation in the presence of WR-2721 were studied in mice and dogs. Histological evaluation of mouse salivary glands irradiated with 1000 rads of ⁶⁰Co showed essentially no difference between control and experimental animals. Almost full regeneration of the serous salivary components occurred by 6 months in both groups and neither group had changes in the mucous glands. The use of higher doses of radiation in the mouse was prevented …

The Effects Of A Drug-Induced Stress On The Contrafreeloading Phenomenon In Rats, Jeanne Bennett

Masters Theses & Specialist Projects

The purpose of this experiment was to determine if stress, induced by intraperitoneal (IP) injections of epinephrine, influenced rats' preference to freeload (drink sucrose solution from a drinking tube) or to work for a liquid reinforcer (obtain sucrose solution by barpressing). Furthermore, the order in which stress was introduced was investigated.

Following two weeks of water deprivation, 6 female and 6 male Hooded rats approximately 90 days old were divided into two experimental groups. The first group (S-N) was stressed the first and second experimental testing days in which a choice was presented between barpressing and freeloading for a 10% …